4-Morpholinepropanesulfonic acid, sodium salt (1:1)
SODIUM 3-MORPHOLINOPROPANESULFONATE · MOPS-NA · MOPS, SODIUM · MOPS Na-salt · MOPSsodiumsal · MOPS sodium sa · MOPS SODIUM SALT · MOPSsodiumsalt,98%
식별자 및 물리적 특성
| CAS No. | 117961-20-3 |
|---|---|
| 분자식 | C7H14NNaO4S |
| 평균 분자량 | 231.25 g/mol |
| 단동위원소 질량 | 231.05412338 g/mol |
| SMILES | O=S(=O)([O-])CCCN1CCOCC1.[Na+] |
| InChIKey | MWEMXEWFLIDTSJ-UHFFFAOYSA-M |
| PubChem CID | 3859613 |
| EC No. | 428-420-3 |
| DTXSID | DTXSID3072246 |
화학 및 물리적 성질
| 극성 표면적 | 78.1 |
|---|---|
| 수소 결합 공여자 수 | 0 |
| 수소 결합 수용자 수 | 5 |
| 회전 가능 결합 수 | 4 |
| 무거운 원자 수 | 14 |
| 형식 전하 | 0 |
| 복잡도 | 233 |
| 녹는점 | 277-282°C |
| 밀도 | 1.41[at 20℃] |
| 저장 조건 | room temp |
| 용해도 | H2O: 1 M at 20 °C, 투명, 무색 |
| 물리적 상태 | 분말/고체 |
| 색상 | 하얀색 |
| pH | 10.0-12.0 (1M in H2O) |
| pKa(산도 계수) | 7.2(at 25℃) |
| 생물학적 소스 | synthetic |
| 용해도 | 물에 용해됩니다(20°C에서 523g/L). |
| 주요 응용 | 진단 검사 제조 |
| InChI | 1S/C7H15NO4S.Na/c9-13(10,11)7-1-2-8-3-5-12-6-4-8/h1-7H2,(H,9,10,11)/q+1/p-1 |
| InChIKey | MWEMXEWFLIDTSJ-UHFFFAOYSA-M |
| SMILES | [Na+].[O-]S(=O)(=O)CCCN1CCOCC1 |
| EPA | 4-Morpholinepropanesulfonic acid, sodium salt (71119-22-7) |
| Absorption | ≤0.1 at 260 in H2O at 1M≤0.1 at 280 in H2O at 1M |
화학적 성질
white powder
안전 및 규제
| GHS 분류 | This chemical does not meet GHS hazard criteria for 4.2% (2 of 48) of reports.WarningH315 (93.8%): Causes skin irritation [Warning Skin corrosion/irritation]P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 48 reports by companies from 4 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.This chemical does not meet GHS hazard criteria for 100% (11 of 11) of all reports. |
|---|---|
| 규제 정보 | PMN - indicates a commenced PMN (Pre-Manufacture Notices) substance.REACH registered substance: Sodium 3-morpholin-4-ylpropane-1-sulfonate (EC: 428-420-3)4-Morpholinepropanesulfonic acid, sodium salt: Does not have an individual approval but may be used under an appropriate group standard |
| Hazard Classes and Categories | Skin Irrit. 2 (93.8%)Not Classified |
| 수질 위해 등급(WGK) | 1 |
| TSCA 등재 상태 | TSCA listed |
| 관세 코드 | 29349097 |
| 위험 문구(R) | 36/37/38 |
| 위험 표시 | Xi |
| 안전 문구(S) | 24/25-36-26 |
| F 고인화성물질 | 10 |
| 저장 분류 | 13 - Non Combustible Solids |
용도
개요
MOPS sodium salt is a buffering agent used in biochemistry and molecular biology that was selected and described by Good et al. It is a zwitterionic, morpholinic buffer that is useful for a pH range of 6.5 – 7.9 and commonly used for cell culture media, as a running buffer in electrophoresis and for protein purification in chromatography. MOPS lacks the ability to form a complex with most metal ions and is recommended for use as a non-coordinating buffer in solutions with metal ions. MOPS is often used in buffered culture media for bacteria, yeast, and mammalian cells. MOPS is regarded as an excellent buffer for use in separating RNA in agarose gels. It is recommended to sterilize MOPS buffers by filtration rather than with autoclave due to the unknown identity of yellow degradation products that occur after sterilization of MOPS with autoclave. It is suitable for use in the bicinchoninic acid (BCA) assay.MOPS sodium salt can be mixed with MOPS free acid to attain desired pH. Alternatively, MOPS free acid can be titrated with sodium hydroxide to attain desired pH.
용도
MOPS Sodium Salt is a buffering agent used in organic chemistry.