Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Flunixin Meglumine
FLUNIXIN MEGLUMINE · flunixin meglumin · Flunixin Meglunine · BANAMINE · 1-deoxy-1-(methylamino)-d-glucito2-((2-methyl-3-(trifluoromethyl)phenyl)am · Finadyne · Equileve · NIH 10250
식별자 및 물리적 특성
| CAS No. | 42461-84-7 |
|---|---|
| 분자식 | C21H28F3N3O7 |
| 평균 분자량 | 491.5 g/mol |
| SMILES | CNC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO.Cc1c(Nc2ncccc2C(=O)O)cccc1C(F)(F)F |
| InChIKey | MGCCHNLNRBULBU-WZTVWXICSA-N |
| PubChem CID | 39212 |
| ChEMBL | CHEMBL1733447 |
| ChEBI | CHEBI:76144 |
| EC No. | 255-836-0 |
화학 및 물리적 성질
| 극성 표면적 | 175 |
|---|---|
| 수소 결합 공여자 수 | 8 |
| 수소 결합 수용자 수 | 13 |
| 회전 가능 결합 수 | 9 |
| 무거운 원자 수 | 34 |
| 형식 전하 | 0 |
| 복잡도 | 510 |
| 의약품 | DEA NFLIS-Drug Category -> Analgesics |
| Animal Drugs | Active Ingredients (Flunixin Meglumine) -> FDA Greenbook |
| 녹는점 | 136.6-137.4 °C |
| 저장 조건 | room temp |
| 용해도 | H2O: 자유롭게 용해됨 |
| 물리적 상태 | 고체 |
| 색상 | 회백색 |
| 용해도 | 녹는 |
| InChIKey | MGCCHNLNRBULBU-WZTVWXICSA-N |
| SMILES | CNC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO.Cc1c(Nc2ncccc2C(O)=O)cccc1C(F)(F)F |
화학적 성질
White Solid
안전 및 규제
| GHS 분류 | This chemical does not meet GHS hazard criteria for 0.5% (1 of 215) of reports.DangerH301 (79.5%): Toxic if swallowed [Danger Acute toxicity, oral]P260, P261, P264, P264+P265, P270, P271, P273, P280, P284, P301+P316, P302+P352, P304+P340, P305+P351+P338, P305+P354+P338, P316, P317, P319, P320, P321, P330, P332+P317, P337+P317, P362+P364, P391, P403+P233, P405, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 215 reports by companies from 21 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies. |
|---|---|
| 규제 정보 | Flunixin meglumine: Does not have an individual approval but may be used as a component in a product covered by a group standard. It is not approved for use as a chemical in its own right. |
| 기타 안전 정보 | IMAP assessments - D-Glucitol, 1-deoxy-1-(methylamino)-, 2-[[2-methyl-3-(trifluoromethyl)phenyl]amino]-3-pyridinecarboxylate (salt): Environment tier I assessment |
| Hazard Classes and Categories | Acute Tox. 3 (79.5%) |
| 수질 위해 등급(WGK) | 3 |
| RTECS 번호 | LZ4367000 |
| 운송 번호(UN) | UN 2811 6.1 / PGI |
| 관세 코드 | 29339900 |
| 위험 문구(R) | 36/37/38 |
| 위험 표시 | Xi |
| 안전 문구(S) | 26-36 |
| 위험 등급 | Eye Irrit. 2Skin Irrit. 2STOT SE 3 |
| 저장 분류 | 11 - Combustible Solids |
용도
용도
Flunixin meglumine has been used as a nonsteroidal anti-inflammatory drug standard in electrospray ionization mass spectrometry (LC-ESI/MS).
일반 설명
Flunixin meglumine is a nonsteroidal anti-inflammatory drug and a potent cyclo-oxygenase (COX) inhibitor. It is commonly used as an analgesic and antipyretic in animals.Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.