아인산
아인산 · 아인산45%용액 · 아인산용액 · 포스폰산 · 포스포닉산 · 인(III)산 · Phosphorous acid · PHOSPHONIC ACID
식별자 및 물리적 특성
| CAS No. | 13598-36-2 |
|---|---|
| 분자식 | H3O3P |
| 평균 분자량 | 81.996 g/mol |
| 단동위원소 질량 | 81.98198095 g/mol |
| SMILES | O=[PH](O)O |
| InChIKey | ABLZXFCXXLZCGV-UHFFFAOYSA-N |
| PubChem CID | 407 |
| ChEMBL | CHEMBL1235291 |
| EC No. | 237-066-7 |
| DTXSID | DTXSID2049715 |
| 현지명 | 아인산 |
화학 및 물리적 성질
| XLogP | -1.6 |
|---|---|
| 극성 표면적 | 57.5 |
| 수소 결합 공여자 수 | 2 |
| 수소 결합 수용자 수 | 3 |
| 회전 가능 결합 수 | 0 |
| 무거운 원자 수 | 4 |
| 형식 전하 | 0 |
| 복잡도 | 26 |
| Physical Description | Dry PowderLiquidLarge CrystalsCBI |
| 녹는점 | 73 °C |
| 끓는 점 | 200 °C |
| 밀도 | 1.651 g/mL at 25 °C(lit.) |
| 증기압 | 0.001Pa at 20℃ |
| 인화점 | 200°C |
| 저장 조건 | 0-6°C |
| 용해도 | DMSO(약간 용해됨), 메탄올(약간 용해됨), 물(소량으로 용해) |
| 물리적 상태 | 크리스탈 |
| pKa(산도 계수) | pK1 1.29pK2 6.74(at 25℃) |
| 비중 | 1.651 |
| 색상 | 하얀색 |
| pH | pKa1= 1.10, pKa2 = 6.33(25℃) |
| 용해도 | 녹는 |
| Merck | 14,7346 |
| 안정성 | 안정적인. 강한 염기와 호환되지 않습니다. 흡습성. |
| InChI | 1S/H3O3P/c1-4(2)3/h4H,(H2,1,2,3) |
| InChIKey | ABLZXFCXXLZCGV-UHFFFAOYSA-N |
| SMILES | [H]P(O)(O)=O |
| NIST | (HO)2HPO(13598-36-2) |
| EPA | Phosphonic acid (13598-36-2) |
화학적 성질
Phosphorous acid is a white crystalline deliquescent solid that can be prepared by the action of water on phosphorus( III) oxide or phosphorus(III) chloride. It is a dibasic acid producing the anions H2PO3- and HPO3 2- in water. The acid and its salts are slow reducing agents. On warming, phosphonic acid decomposes to phosphine and phosphoric(V) acid. Phosphorus acid is used to prepare phosphite salts. It is usually sold as a 20% aqueous solution.
안전 및 규제
| GHS 분류 | DangerH302: Harmful if swallowed [Warning Acute toxicity, oral]H314: Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]P260, P264, P270, P280, P301+P317, P301+P330+P331, P302+P361+P354, P304+P340, P305+P354+P338, P316, P321, P330, P363, P405, and P501 (click each P-code to see the statement)This chemical does not meet GHS hazard criteria for 0.1% (2 of 1718) of reports. |
|---|---|
| 규제 정보 | Chemical: Phosphonic acidCommission Regulation No 844/2012Phosphonic acid is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Phosphonic acid are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)Status: Active Update: 16-02-2023 https://echa.europa.eu/registration-dossier/-/registered-dossier/15806Ortho phosphorous acid: Does not have an individual approval but may be used under an appropriate group standardThe New Jersey Worker and Community Right to Know Act requires public and private employers to provide information about hazardous substances at their workplaces. (N.J.S.A. 34:5A-1 et. seq.) |
| 기타 안전 정보 | IMAP assessments - Phosphonic acid: Human health tier II assessmentIMAP assessments - Phosphonic acid: Environment tier I assessment |
| EPA Safer Chemical | Chemical: Phosphonic acidYellow triangle - The chemical has met Safer Choice Criteria for its functional ingredient-class, but has some hazard profile issues. Specifically, a chemical with this code is not associated with a low level of hazard concern for all human health and environmental endpoints. (See Safer Choice Criteria). While it is a best-in-class chemical and among the safest available for a particular function, the function fulfilled by the chemical should be considered an area for safer chemistry innovation. |
| Hazard Classes and Categories | Met. Corr. 1 (22.3%)Acute Tox. 4 (98.6%)Skin Corr. 1 (99.9%)Eye Dam. 1 (47.1%)STOT SE 3 (26%)Acute toxicity - category 4Skin corrosion - category 1ASelf-reactive substances and mixtures - Type GAcute toxicity (Oral) - Category 4Skin corrosion/irritation - Category 1Serious eye damage/eye irritation - Category 1CorrosivesAcute Tox. 4 *Skin Corr. 1A |
| Protective Action Criteria (PAC) | 5.7 [mg/m3]63 [mg/m3]380 [mg/m3] |
| 수질 위해 등급(WGK) | 1 |
| TSCA 등재 상태 | TSCA listed |
| RTECS 번호 | SZ6400000 |
| 운송 번호(UN) | UN 2834 |
| 관세 코드 | 28092019 |
| 위험 문구(R) | 22-35 |
| 위험 표시 | C |
| 안전 문구(S) | 26-36/37/39-45 |
| 포장분류 | III |
| 위험 등급 | 8Acute Tox. 4 OralEye Dam. 1Met. Corr. 1Skin Corr. 1A |
| 기존화학 물질 | KE-28491 |
| F 고인화성물질 | 3 |
| 저장 분류 | 8A - Combustible corrosive hazardous materials |
용도
개요
Phosphorous acid, H3PO3, is diprotic (readily ionizes two protons), not triprotic as might be suggested by this formula. Phosphorous acid is as an intermediate in the preparation of other phosphorous compounds. Because preparation and uses of “phosphorous acid” actually pertain more to the major tautomer, phosphonic acid, it is more often referred to as “phosphorous acid”. Phosphorous acid has the chemical formula H3PO3, which is best expressed as HPO(OH)2 to show its diprotic character. P(OH)3 (IUPAC: phosphorous acid) has CAS number 10294-56-1. It has been shown to be a stable tautomer.
용도
Phosphorous acid is used to produce the fertilizer phosphate salt like potassium phosphite, ammonium phosphite and calcium phosphite. It is actively involved in the preparation of phosphites like aminotris(methylenephosphonic acid) (ATMP), 1-hydroxyethane 1,1-diphosphonic acid (HEDP) and 2-phosphonobutane-1,2,4-tricarboxylic Acid (PBTC), which find application in water treatment as a scale or corrosive inhibitor. It is also used in chemical reactions as a reducing agent. Its salt, lead phosphite is used as PVC stabilizer. It is also used as a precursor in the preparation of phosphine and as an intermediate in the preparation of other phosphorus compounds.
일반 설명
Phosphorous acid appears as a white or yellow crystalline solid (melting point 70.1°C) or a solution of the solid. Density 1.651 g /cm3 . Contact may severely irritate skin, eyes, and mucous membranes. Toxic by ingestion, inhalation and skin absorption.
제조 및 합성 방법
제조 방법
Phosphorus acid can be prepared by the reaction of phosphorus trichloride with water: PCl3 + 3H2O → H3PO4 + 3HClThe reaction is violent. Addition of PCl3 should be extremely cautious and slow. The addition can be carried out safely in the presence of concentrated HCl. Alternatively, a stream of air containing PCl3 vapor is passed into icecold water and solid crystals of H3PO4 form. Alternatively, phosphorus acid can be prepared by adding phosphorus trichloride to anhydrous oxalic acid: PCl3 + 3(COOH）2 → H3PO3 + 3CO + 3CO2 + 3HCl In this reaction, all products except H3PO3 escape as gases leaving the liquid acid. Dissolution of phosphorus sesquioxide in water also forms phosphorus acid. When shaken with ice water, phosphorus acid is the only product . P4O6 + 6H2O → 4H3PO3 However, in hot water part of the phosphorus acid disproportionates to phosphoric acid and phosphorus or phosphine.