6-Amino-o-cresol (HCID 413657)

이름 및 식별자

우선 이름: 6-Amino-o-cresol
IUPAC: 2-amino-6-methylphenol
현지명: 6-아미노-o-크레솔
영어명: 6-Amino-2-methylphenol
분자식: C7H9NO
분자량: 123.15

이름 및 동의어

2-amino-6-methylphenol17672-22-96-Amino-2-methylphenol6-Amino-o-cresolPhenol, 2-amino-6-methyl-o-Cresol, 6-amino-6-Methyl-2-aminophenol6-Methyl-o-aminophenolUNII-4N899ESJ5B6-Amino-o-cresol [INCI]4N899ESJ5BDTXSID80170179

이름 더 보기

6-아미노-o-크레솔6-아미노-o-크레솔및그염류,염모제로사용될때2-methyl-6-aminophenol6- aMinocresolASISCHEM D509546-AMINO-ORTHO-CRESOL2-Amino-6-methylpheno6-Amino-o-methylphenol6-AMINO-O-CRESOL, 99.5%

2A6MP6-Amino-o-creosolRefChem:104199DTXCID9092670605-780-12-Amino-6-methyl-phenolMFCD03788432Amino-hydroxy-methyl-benzol

데이터베이스 식별자

CAS: 17672-22-9
PubChem CID: 413657
DTXSID: DTXSID80170179
ChEMBL: CHEMBL5542658
UNII: 4N899ESJ5B
EC Number: 605-780-1
Nikkaji: J1.712.101D

물성

구조 계산 물성

XLogP: 1.5
극성 표면적: 46.3 Å²
수소 결합 공여자 수: 2
수소 결합 수용자 수: 2
회전 가능 결합 수: 0
무거운 원자 수: 9
형식 전하: 0
복잡도: 94

물리화학적 성질

녹는점: 86 ℃ · 86℃
끓는 점: 232.9 · 232.9±28.0 °C(Predicted)
밀도: 1.157 · 1.157±0.06 g/cm3(Predicted)
저장 조건: 2 · 2-8°C(protect from light)
산도 계수 (pKa): 10.1 · 10.10±0.10(Predicted)
화장품 원료 기능: 머리 염색
InChI: 1S/C7H9NO/c1-5-3-2-4-6(8)7(5)9/h2-4,9H,8H2,1H3
InChIKey: ALQKEYVDQYGZDN-UHFFFAOYSA-N
SMILES: Cc1cccc(N)c1O

화학적 성질

Appearance:Light yellow crystal powder

안전 및 규제

GHS 분류

GHS Classification · 5건

Warning

H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]；H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]；H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]；H335 (100%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 39 reports by companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.；Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

유해성 정보

Regulatory InformationChemical: Phenol, 2-amino-6-methyl-

Other Safety InformationIMAP assessments - Chemicals with limited data availability that may be used in hair dyes overseas: Human health tier II assessment；IMAP assessments - Phenol, 2-amino-6-methyl-: Environment tier I assessment

Hazard Classes and CategoriesAcute Tox. 4 (100%)；Skin Irrit. 2 (100%)；Eye Irrit. 2A (100%)；STOT SE 3 (100%)

독성 정보

Toxicity Summary · 2건

The Expert Panel for Cosmetic Ingredient Safety concluded that the available data are insufficient to make a determination of safety for 6-Amino-o-Cresol under the intended conditions of use as a hair dye ingredient.

Safe for use in cosmetics, with qualifications

규제 정보

Regulatory InformationChemical: Phenol, 2-amino-6-methyl-

안전 데이터

wgk: WGK 3
HS 번호: 29222990
risk_code: 22-36/37/38
hazard_code: Xn
safety_code: 26
위험 등급: IRRITANT
Hazard Classifications: Acute Tox. 4 OralEye Irrit. 2Skin Irrit. 2STOT SE 3
스토리지 클래스: 11 - Combustible Solids

화학 및 산업

용도 및 제조

UsesCIR ingredient: 6-Amino-o-Cresol

Use ClassificationCosmetics -> Hair dyeing

응용 분야 · 1건

용도6-Amino-2-methylphenol is a colorant that has been classified as a skin sensitizer. It is used in the manufacture of inorganic pigments and other organic compounds, such as dyes and paints. 6-Amino-2-methylphenol absorbs ultraviolet radiation and reacts with chloride to form 2-amino, 6-(chloromethyl) phenol, which has been shown to have subchronic toxicity. This chemical also photodegrades in sunlight, producing free radicals that can damage cells.