기본 정보
- CAS
55-40-3- 표준 SMILES
CC(N)(Cc1ccc(O)c(O)c1)C(=O)O- InChIKey
CJCSPKMFHVPWAR-UHFFFAOYSA-N- 분자식
- C10H13NO4
- 평균 분자량
- 211.21 g/mol
- 단동위원소 질량
- 211.0844579
개요
3-Hydroxy-alpha-methyl-DL-tyrosine is a member of benzenes and a monocarboxylic acid.
이름 및 식별자
- 우선 이름
- Alpha-methyldopa
- IUPAC
- 2-amino-3-(3,4-dihydroxyphenyl)-2-methylpropanoic acid
- 현지명
- 3-하이드록시-알파-메틸-DL-티로신
- 영어명
- 3-Hydroxy-alpha-methyl-DL-tyrosine
- 분자식
- C10H13NO4
- 분자량
- 211.21
이름 및 동의어
MulfasinMetholesalpha-MethyldopaEINECS 209-088-7EINECS 200-232-4LMethyldopaalphaMethylLdopaLalphaMethyldopa()MethyldopaL(alphaMd)RefChem:5558743HydroxyalphamethylLtyrosine
이름 더 보기
3-하이드록시-알파-메틸-DL-티로신MethydopaDL-METHYLDOPADL-A-METHYL DOPATIMTEC-BB SBB000508DL-ALPHA-METHYL-DOPA(rs)-alpha-methyldopa(+-)-alpha-methyldoparacemicalpha-methyldopa
alphaMethylL3,4dihydroxyphenylalanineLalphaMethyl3,4dihydroxyphenylalanine3(3,4Dihydroxyphenyl)2methylLalanineL()3(3,4Dihydroxyphenyl)2methylalaninealphaMethylbeta(3,4dihydroxyphenyl)LalanineL()alphaMethylbeta(3,4dihydroxyphenyl)alanineL()beta(3,4Dihydroxyphenyl)alphamethylalanineL2Amino2methyl3(3,4dihydroxyphenyl)propionic acid
데이터베이스 식별자
- CAS
55-40-3、555-29-3、555-30-6- PubChem CID
- 4138
- DTXSID
DTXSID60970356
물성
구조 계산 물성
- XLogP
- -1.9
- 극성 표면적
- 104 Ų
- 수소 결합 공여자 수
- 4
- 수소 결합 수용자 수
- 5
- 회전 가능 결합 수
- 3
- 무거운 원자 수
- 15
- 형식 전하
- 0
- 복잡도
- 246
실험 및 물리화학적 성질
Chemical ClassesOther Uses -> Pharmaceuticals
Human DrugsBreast Feeding; Lactation; Milk, Human; Antihypertensive Agents; Adrenergic alpha-2 Receptor Agonists
Dissociation Constants2.21
물리화학적 성질
- 저장 조건
- 20 °C · −20°C
안전 및 규제
안전 정보는 참고용이며, 공급업체의 물질안전보건자료(SDS), 관련 법규 및 전문가 평가를 대체하지 않습니다.
GHS 분류
GHS Classification
Warning
H315 (19.1%): Causes skin irritation [Warning Skin corrosion/irritation]
P264, P264+P265, P280, P302+P352, P305+P351+P338, P321, P332+P317, P337+P317, and P362+P364 (click each P-code to see the statement)
Aggregated GHS information provided per 47 reports by companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
유해성 정보
Hazards Summary
Asthma reported in the pharmaceutical industry; [Malo] As an oral medication, methyldopa is used to treat hypertension. Many side effects have been reported after ingestion of therapeutic doses, including immune hemolytic anemia and drug-induced hepatitis. [HSDB]
Hazard Classes and CategoriesSkin Irrit. 2 (19.1%)
독성 정보
Adverse EffectsOccupational hepatotoxin - Secondary hepatotoxins: the potential for toxic effect in the occupational setting is based on cases of poisoning by human ingestion or animal experimentation.
Effects During Pregnancy and Lactation◉ Summary of Use during Lactation
안전 데이터
- wgk
- 3
- risk_code
- 36
- hazard_code
- Xi
- safety_code
- 26-36/37
화학 및 산업
약리 정보
ATC Code
C - Cardiovascular system
QC - Cardiovascular system
상·하류 제품 정보
하류 제품
공급사27 곳
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