Kathon (HCID 41679)｜Huagongshe

개요

industrial biocide & cosmetic preservative formulation; contains methylcholoro-isothiazolinone and methylcholoroisothiazolinone

이름 및 식별자

우선 이름: Kathon
IUPAC: 5-chloro-2-methyl-1,2-thiazol-3-one;2-methyl-1,2-thiazol-3-one
영어명: Methylchloroisothiazolinone/methylisothiazolinone mixture (MCIT/MIT)
분자식: C4H5NOS.C4H4ClNOS
분자량: 264.75

이름 및 동의어

55965-84-9Kathon 886Kathon LX15O9QS218W3(2H)-Isothiazolone, 5-chloro-2-methyl-, mixt. with 2-methyl-3(2H)-isothiazoloneKathon 886 biocideMBC-215RefChem:151011KathonKathon biocideKathon CGKathon 886MW

이름 더 보기

Isothiazolinone chloride5-Chloro-2-methyl-3(2H)-isothiazolone with 2-methyl-3(2H)-isothiazoloneCon WTNeoCideSidchem 715CMIT/MIT 1.5CGCMIT/MIT B/PLUSCMI/MI Kathon 886

Zonen FProClin 3002-Methylisothiazol-3(2H)-one compound with 5-chloro-2-methylisothiazol-3(2H)-one(14%in H2O)2-Methylisothiazol-3(2H)-one compound with 5-chloro-2-methylisothiazol-3(2H)-one5-chloro-2-methyl-1,2-thiazol-3-one;2-methyl-1,2-thiazol-3-oneBio-Perge5-Chloro-2-methyl-3(2H)-isothiazolone mixt. with 2-methyl-3(2H)-isothiazoloneKathon WT

데이터베이스 식별자

CAS: 55965-84-9
PubChem CID: 41679
ChEMBL: CHEMBL108095
EC Number: 611-341-5、911-418-6、932-593-5

물성

구조 계산 물성

극성 표면적: 91.2 Å²
수소 결합 공여자 수: 0
수소 결합 수용자 수: 4
회전 가능 결합 수: 0
무거운 원자 수: 15
형식 전하: 0
복잡도: 277

실험 및 물리화학적 성질

FragrancesFragrance Ingredient (3(2H)_-_Isothiazolone, 5-_chloro-_2-_methyl-_, mixt. with 2-_methyl-_3(2H)_-_isothiazolone) -> IFRA transparency List

Food Contact SubstancesFCS -> FDA Inventory of Food Contact Substances Listed in 21 CFR

Physical DescriptionLiquid

물리화학적 성질

끓는 점: 100.1 ℃ · 100.1℃ at 101.325kPa
밀도: 20 · d20 1.19
증기압: 0.003 · 0.003-17Pa at 20-45℃
저장 조건: Sealed in dry,Room Temperature
용해도: Chloroform (Soluble), DMSO (Slightly), Methanol (Slightly), Water
물리적 상태: 액체
색상: Colorless to light yellow
수소이온지수(pH): 3.43 at · 3.43 at 20℃ and 10g/L
InChI: InChI=1S/C4H4ClNOS.C4H5NOS/c1-6-4(7)2-3(5)8-6;1-5-4(6)2-3-7-5/h2H,1H3;2-3H,1H3
InChIKey: QYYMDNHUJFIDDQ-UHFFFAOYSA-N
SMILES: O=C1C=C(SN1C)Cl.O=C1C=CSN1C
LogP: -0.34 · -0.34-0.81 at 10-30℃ and pH5-9
표면장력: 72.6 · 72.6-73mN/m at 1-1.106g/L and 19.5-20℃
EPA: 5 · 5-Chloro-2-methyl-3(2H)-isothiazolone mixt. with 2-methyl-3(2H)-isothiazolone (55965-84-9)

안전 및 규제

GHS 분류

GHS Classification · 6건

Danger

H301: Toxic if swallowed [Danger Acute toxicity, oral]

P260, P261, P262, P264, P264+P265, P270, P271, P272, P273, P280, P284, P301+P316, P301+P330+P331, P302+P352, P302+P361+P354, P304+P340, P305+P354+P338, P316, P317, P320, P321, P330, P333+P317, P361+P364, P362+P364, P363, P391, P403+P233, P405, and P501 (click each P-code to see the statement)

This chemical does not meet GHS hazard criteria for < 0.1% (1 of 1945) of reports.

Danger

H301 (99.8%): Toxic if swallowed [Danger Acute toxicity, oral]

유해성 정보

Regulatory Information · 3건

3(2H)-Isothiazolone, 5-chloro-2-methyl-, mixt. with 2-methyl-3(2H)-isothiazolone is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of 3(2H)-Isothiazolone, 5-chloro-2-methyl-, mixt. with 2-methyl-3(2H)-isothiazolone are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

Status: Active Update: 14-03-2022 https://echa.europa.eu/registration-dossier/-/registered-dossier/23870

Mixture of methylchloroisothiazolinone and methylisothiazolinone: Does not have an individual approval but may be used under an appropriate group standard

Other Safety InformationPEC / SN / Other assessments - Common skin sensitisersâhazard classification: Health

Hazard Classes and Categories · 5건

Acute Tox. 3 (99.8%)

Acute Tox. 3 (100%)

Acute Tox. 4 (100%)

Acute toxicity (inhalation) - category 2

Acute Tox. 2

안전 데이터

독성: LD50 (mg/kg) orally in rabbits: 30; i.p. in male, female rats: 4.6, 4.3; LC50 (6 day) in trout, sunfish (mg/l): 0.14, 0.54; LC50 (8 day dietary) in Bobwhite quail, Peking duck (mg/kg/day): >60, >100 (J. Am. Coll. Toxicol.)
기존화학 물질: KE-05738
함량 및 규제정보: 물질구분: 유독물질; 혼합물(제품)함량정보: 5-클로로-2-메틸-4-이소티아졸린-3-온 및 이를 1% 이상 함유한 혼합물
유해화학물질 필터링: 2012-1-644, 2012-1-645

화학 및 산업

약리 정보

MeSH Pharmacological ClassificationChemical agents that increase the rate of genetic mutation by interfering with the function of nucleic acids. A clastogen is a specific mutagen that causes breaks in chromosomes.

용도 및 제조

U.S. Production2023: <50,000 lb

Consumer UsesNot Known or Reasonably Ascertainable

Industry UsesNot Known or Reasonably Ascertainable

Household ProductsInformation on 63 consumer products that contain Kathon biocide in the following categories is provided:

Use ClassificationFragrance Ingredients

General Manufacturing InformationNot Known or Reasonably Ascertainable

응용 분야 · 4건

개요CMIT / MIT 혼합물은 활성 성분의 혼합물에 기초한 이소 티아 졸리 논 유도 살 생물 제이다 : 5- 클로로 -2- 메틸 -2H- 이소 티아 졸 -3- 온 및 2- 메틸 -2H- 이소 티아 졸 -3- 온 (CMIT / MIT)을 3 : 1의 비율로 포함하는 것 인 방법.

용도CMIT / MIT 혼합물은 산업 및 가정용 응용 프로그램의 미생물 성장 과정 수를 제어하는 데 사용할 수 있습니다. 그람 양성균과 그람 음성균, 효모 및 진균류에 효과적입니다.

개요Kathon 886 metalwork fluid is a mixture of the two isothiazoliones contained in Kathon CG, at a 13.9% concentration. It is mainly contained in metalwork fluids. As an active component of Aigezid Ⅱ and contained in a water bath used for phtotographic development, it caused contact dermatitis in a photograph developer.

용도Antimicrobial preservative in cosmetics, hygeine products, paints, emulsions, cutting oils, paper coatings, and water storage and cooling units.

상·하류 제품 정보

상류 원료

메틸아민

공급사50 곳

郑州阿尔法化工有限公司+86-18530059196 · [email protected]

湖北永阔科技有限公司027-59223108 15972152991 · [email protected]

湖北万得化工有限公司15377098680 15377098680 · [email protected]

南通润丰石油化工有限公司66017690 19952660367 · [email protected]

武汉欣扬瑞和化学科技有限公司13720274133 · [email protected]

연결된 노트

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Kathon

기본 정보

개요