(2E)-2-(니트로메틸리덴)-1,3-티아지난
(2E)-2-(니트로메틸리덴)-1,3-티아지난 · nithiazine · SD 35651 · (2E)-2-(nitromethylidene)-1,3-thiazinane · tetrahydro-2-(nitromethylene)-2H-1,3-thiazine · 2H-1,3-Thiazine, tetrahydro-2-(nitromethylene)-
식별자 및 물리적 특성
| CAS No. | 58842-20-9 |
|---|---|
| 분자식 | C5H8N2O2S |
| 평균 분자량 | 160.2 g/mol |
| 단동위원소 질량 | 160.0306485 g/mol |
| SMILES | O=[N+]([O-])C=C1NCCCS1 |
| InChIKey | LZTIMERBDGGAJD-UHFFFAOYSA-N |
| PubChem CID | 42853 |
| ChEMBL | CHEMBL3138618 |
| DTXSID | DTXSID7034256 |
| 현지명 | (2E)-2-(니트로메틸리덴)-1,3-티아지난 |
화학 및 물리적 성질
| XLogP | 1.2 |
|---|---|
| 극성 표면적 | 83.2 |
| 수소 결합 공여자 수 | 1 |
| 수소 결합 수용자 수 | 4 |
| 회전 가능 결합 수 | 0 |
| 무거운 원자 수 | 10 |
| 형식 전하 | 0 |
| 복잡도 | 164 |
| 끓는 점 | 287.9±40.0 °C(Predicted) |
| 밀도 | 1.387±0.06 g/cm3(Predicted) |
| 용해도 | 클로로포름(약간 용해됨), 메탄올(약간 용해됨) |
| 물리적 상태 | 고체 |
| pKa(산도 계수) | 1.16±0.20(Predicted) |
| 색상 | 황백색에서 밝은 노란색까지 |
| 안정성 | 감광성 |
| EPA | Nithiazine (58842-20-9) |
안전 및 규제
| 운송 번호(UN) | 2588 |
|---|---|
| 포장분류 | III |
| 위험 등급 | 6.1(b) |
용도
개요
Nithiazine and other members of the nitromethylene family were shown at an early stage in their development to be cholinergic agonists (and antagonists) by electrophysiology (6). However, unlike nicotine, they mostly act as partial agonists and are open channel blockers, a property resulting from their partial positive charge.
용도
Nithiazine is used as an active ingredient in fly strips (e.g., QuickStrikes Fly Abatement Strip, Sandoz 9023 fly bait station). The strips are most effective against houseflies (Musca domestica). They can be placed in or around the house, animal housing, recycling facilities, or other facilities where abundant houseflies are a nuisance; however, the manufacturer currently does not support residential uses.