FE나RIM올

Fenarimol

HCID 43226CAS 60168-88-9
부분 구조 검색유사 구조 찾기

기본 정보

표준 SMILES
OC(c1ccc(Cl)cc1)(c1cncnc1)c1ccccc1Cl
InChIKey
NHOWDZOIZKMVAI-UHFFFAOYSA-N
분자식
C17H12Cl2N2O
평균 분자량
331.2 g/mol
단동위원소 질량
330.03266836

개요

Pure white crystalline solid. Used as a fungicide. Irritates skin and mucous membranes.

이름 및 식별자

우선 이름
Fenarimol
IUPAC
(2-chlorophenyl)-(4-chlorophenyl)-pyrimidin-5-ylmethanol
현지명
FE나RIM올
영어명
Fenarimol
분자식
C17H12Cl2N2O
분자량
331.2

이름 및 동의어

FENARIMOL60168-88-9RubiganRimidinDTXSID2032390EL 222FENARIalpha-(2-Chlorophenyl)-alpha-(4-chlorophenyl)-5-pyrimidinemethanolO088GU930Q2,4'-Dichloro-alpha(pyrimidin-5-yl)benzhydryl alcoholDTXCID0012390(+-)-2,4'-Dichloro-alpha-(pyrimidin-5-yl)benzhydryl alcohol
이름 더 보기
FE나RIM올FE나RIM올(FENARIMOL)페나리몰페나림올BlocEL-222BLOC(R)RUBIGAN-4RUBIGAN(R)RUBIGAN12ECFenarimol Standard
CHEBI:83686(2-chlorophenyl)(4-chlorophenyl)pyrimidin-5-ylmethanol5-Pyrimidinemethanol, alpha-(2-chlorophenyl)-alpha-(4-chlorophenyl)-RefChem:140102CHEBI:4998(2-Chlorophenyl)-alpha-(4-chlorophenyl)-5-pyrimidinemethanol262-095-7(2-Chlorophenyl)(4-chlorophenyl)(pyrimidin-5-yl)methanol

데이터베이스 식별자

CAS
60168-88-9
PubChem CID
43226
DTXSID
DTXSID2032390
ChEMBL
CHEMBL28971
ChEBI
CHEBI:83686
UNII
O088GU930Q
EC Number
262-095-7
Nikkaji
J18.180C

물성

구조 계산 물성

XLogP
3.6
극성 표면적
46 Ų
수소 결합 공여자 수
1
수소 결합 수용자 수
3
회전 가능 결합 수
3
무거운 원자 수
22

실험 및 물리화학적 성질

Pesticides · 4건

Fungicides

Active substance -> EU Pesticides database: Not approved

Fungicides

Pesticide (Fenarimol) -> USDA PDB

LogP2.62
Endocrine DisruptorsPotential endocrine disrupting compound
Melting Point117 - 119 °C
Physical Description · 2건

Pure white crystalline solid. Used as a fungicide. Irritates skin and mucous membranes.

Solid

Collision Cross Section · 3건

176.0 Ų [M-H]- [CCS Type: DT; Buffer gas: N2; Ionization: ESI-; Dataset: TOXCAST; Source Identifier: DTXSID2032390]

175.92 Ų [M-H]-

173.78 Ų [M]+ [CCS Type: TW; Buffer gas: N2; Ionization: GC-APCI+]

물리화학적 성질

녹는점
117 · 117-119°C
끓는 점
0 °C · 0°C
밀도
1.3886 · 1.3886 (rough estimate)
증기압
6.5 x · 6.5 x 10-5 Pa at 25 °C
굴절률
1.549 · 1.5490 (estimate)
인화점
0 °C · 0°C

안전 및 규제

GHS 분류

GHS Classification · 6건

Warning

H361fd: Suspected of damaging fertility; Suspected of damaging the unborn child [Warning Reproductive toxicity]

P203, P260, P263, P264, P270, P273, P280, P318, P391, P405, and P501 (click each P-code to see the statement)

Warning

H361 (84.7%): Suspected of damaging fertility or the unborn child [Warning Reproductive toxicity]

P203, P260, P263, P264, P270, P273, P280, P318, P391, P405, and P501 (click each P-code to see the statement)

유해성 정보

Regulatory Information · 4건

Regulation (EC) No 1107/2009 (amended)

Fenarimol is listed in the dataset of EPA Human Health Benchmarks for Pesticides under the Safe Drinking Water Act (40 eCFR 141)

2006/134/EC

Fenarimol: Does not have an individual approval but may be used under an appropriate group standard

Other Safety InformationIMAP assessments - 5-Pyrimidinemethanol, .alpha.-(2-chlorophenyl)-.alpha.-(4-chlorophenyl)-: Human health tier I assessment
DOT LabelPoison Flammable Liquid
Fire HazardsExcerpt from ERG Guide 131 [Flammable Liquids - Toxic]:
Health HazardsExcerpt from ERG Guide 131 [Flammable Liquids - Toxic]:
Reactive GroupAlcohols and Polyols

안전 및 보호

Fire FightingExcerpt from ERG Guide 131 [Flammable Liquids - Toxic]:
First AidExcerpt from ERG Guide 131 [Flammable Liquids - Toxic]:
Nonfire Spill ResponseExcerpt from ERG Guide 131 [Flammable Liquids - Toxic]:
Isolation and EvacuationExcerpt from ERG Guide 131 [Flammable Liquids - Toxic]:
Personal Protective Equipment (PPE)Excerpt from ERG Guide 131 [Flammable Liquids - Toxic]:

독성 정보

Toxicity Summary · 1건

Fenarimol is an antiandrogen. It has effects on the reproductive organs and prostate gene expression levels. Studies suggested that the adverse effects of Fenarimol in males are mediated at least partialy via antagonism or androgen receptor.

Carcinogen ClassificationNo indication of carcinogenicity to humans (not listed by IARC).
RAIS Toxicity Values · 2건

0.006

OPP

EPA Human Health Benchmarks for Pesticides · 5건

Fenarimol

0.006

40

General Population

Human Health Benchmarks for Pesticides - 2021 Update

안전 데이터

wgk
2
tsca
TSCA listed
rtecs
UV9279400
ridadr
UN 3017/3077
독성
LD50 in mice, rats (mg/kg): 4500, 2500 orally (Beraud)
risk_code
51/53-62-63-64

화학 및 산업

약리 정보

MeSH Pharmacological ClassificationChemicals that kill or inhibit the growth of fungi in agricultural applications, on wood, plastics, or other materials, in swimming pools, etc.
Cellular LocationsMembrane

용도 및 제조

Use ClassificationFungicides
General Manufacturing Information5-Pyrimidinemethanol, .alpha.-(2-chlorophenyl)-.alpha.-(4-chlorophenyl)-: ACTIVE
응용 분야 · 2건

용도Fenarimol is a broad spectrum pyrimidine carbinol fungicide with protective, curative and eradicative activities against powdery mildew (Erysiphe spp., Pudusphaera leucutricha, Uncinula necatur, Sphaerutheca spp., Leveillula spp.) and scab (Venturia spp.) in many crops. It also controls powdery mildew (Sphaerutheca pannusa) in ornamentals and Fusarium patch (Micruduccium niuale), Take-all patch (Laefisaria fuciformis), Dollar spot (Sderutina humeucavpa) and red thread (Gaeumannumyces graminis) in turf and amenity grasses.

일반 설명Pure white crystalline solid. Used as a fungicide. Irritates skin and mucous membranes.

상·하류 제품 정보

공급사50 곳

上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
广州佳途科技股份有限公司81960175 18933936954 · [email protected]
河南赢创生物科技有限公司16650615803 · [email protected]
杭州品高化工有限公司0571-87658025 · [email protected]
宁波季诺化学品有限公司0574-87314919 057487319282 · [email protected]

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