기본 정보
- 표준 SMILES
Cl.NCCCC(N)(C(=O)O)C(F)F.O- InChIKey
FJPAMFNRCFEGSD-UHFFFAOYSA-N- 분자식
- C6H15ClF2N2O3
- 평균 분자량
- 236.64 g/mol
- 단동위원소 질량
- 236.07392646
개요
Eflornithine hydrochloride monohydrate is the hydrochloride and hydrate of the trypanocidal drug eflornithine. It is a hydrate and a hydrochloride. It contains an eflornithine.
이름 및 식별자
- 우선 이름
- Ornithine, 2-(difluoromethyl)-, hydrochloride, hydrate (1:1:1)
- IUPAC
- 2,5-diamino-2-(difluoromethyl)pentanoic acid;hydrate;hydrochloride
이름 및 동의어
96020-91-6Eflornithine hydrochloride monohydrateEflornithine HClMDL 71,782 AIwilfin4NH22NDW9HRMI-71782DTXSID4045765DifluromethylornithineCHEBI:47622-(Difluoromethyl)-DL-ornithine monohydrochloride, monohydrateMDL-71782-A
이름 더 보기
RMI-71782-Aalpha-Difluoromethylornithine hydrochlorideDTXCID801477074MDL 71782NSC270295FlorexaEflornithine.HClRefChem:856927
데이터베이스 식별자
- CAS
96020-91-6- PubChem CID
- 441361
- DTXSID
DTXSID4045765- ChEMBL
CHEMBL1201037- ChEBI
CHEBI:4762- UNII
- 4NH22NDW9H
- EC Number
- 619-187-0
물성
구조 계산 물성
- 극성 표면적
- 90.3 Ų
- 수소 결합 공여자 수
- 5
- 수소 결합 수용자 수
- 7
- 회전 가능 결합 수
- 5
- 무거운 원자 수
- 14
- 형식 전하
- 0
- 복잡도
- 166
실험 및 물리화학적 성질
Human Drugs
Breast Feeding; Lactation; Antiparasitic Agents; Antiprotozoal Agents; Enzyme Inhibitors; Trypanocidal Agents
FDA approved drugs -> Active ingredient
FDA approved drugs -> Active ingredient
안전 및 규제
GHS 분류
GHS ClassificationNot Classified
유해성 정보
Hazard Classes and CategoriesNot Classified
독성 정보
Effects During Pregnancy and Lactation◉ Summary of Use during Lactation
화학 및 산업
약리 정보
FDA Pharmacological Classification
EFLORNITHINE HYDROCHLORIDE
Decarboxylase Inhibitor [EPC]; Decarboxylase Inhibitors [MoA]; Antiprotozoal [EPC]
MeSH Pharmacological Classification
Substances that inhibit or prevent the proliferation of NEOPLASMS.
Agents destructive to the protozoal organisms belonging to the suborder TRYPANOSOMATINA.
Substances and drugs that inhibit or block the activity of ORNITHINE DECARBOXYLASE.
관련 반응
8건
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