(-)-Epinephrine hydrochloride

EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.

SMALL SPILLS AND LEAKAGE: If you spill this chemical, you should dampen the solid spill material with water, then transfer the dampened material to a suitable container. Use absorbent paper dampened with water to pick up any remaining material. Seal your contaminated clothing and the absorbent paper in a vapor-tight plastic bag for eventual disposal. Wash all contaminated surfaces with a strong soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned.

RECOMMENDED RESPIRATOR: Where the neat test chemical is weighed and diluted, wear a NIOSH-approved half face respirator equipped with a combination filter cartridge, i.e. organic vapor/acid gas/HEPA (specific for organic vapors, HCl, acid gas, SO2 and a high efficiency particulate filter). (NTP, 1992)

Epinephrine Hydrochloride

TR-380: Toxicology and Carcinogenesis Studies of l-Epinephrine Hydrochloride (CASRN 55-31-2) in F344/N Rats and B6C3F1 Mice (Inhalation Studies) (1990 )

11/20/89

Inadequate Experiment

Inadequate Experiment

Inadequate Experiment

EPINEPHRINE HYDROCHLORIDE

Adrenergic beta-Agonists [MoA]; Adrenergic alpha-Agonists [MoA]; Catecholamines [CS]; Catecholamine [EPC]; alpha-Adrenergic Agonist [EPC]; beta-Adrenergic Agonist [EPC]

Drugs that selectively bind to and activate alpha adrenergic receptors.

Drugs that selectively bind to and activate beta-adrenergic receptors.

Agents that cause an increase in the expansion of a bronchus or bronchial tubes.

Agents that dilate the pupil. They may be either sympathomimetics or parasympatholytics.

Drugs that mimic the effects of stimulating postganglionic adrenergic sympathetic nerves. Included here are drugs that directly stimulate adrenergic receptors and drugs that act indirectly by provoking the release of adrenergic transmitters.

Drugs used to cause constriction of the blood vessels.