티라민염화물

N-Formyl-L-methionyl-L-leucyl-L-phenylalanine

HCID 443295CAS 59880-97-6

기본 정보

표준 SMILES: CSCC[C@H](NC=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)O
InChIKey: PRQROPMIIGLWRP-BZSNNMDCSA-N
분자식: C21H31N3O5S
평균 분자량: 437.6 g/mol
단동위원소 질량: 437.19844209

개요

N-formyl-L-methionyl-L-leucyl-L-phenylalanine is a tripeptide composed of L-Met, L-Leu and L-Phe in a linear sequence with a formyl group at the amino terminus. It acts as a potent inducer of leucocyte chemotaxis and macrophage activator as well as a ligand for the FPR receptor. It is functionally related to a L-leucine, a N-formyl-L-methionine and a L-phenylalanine. It is a conjugate acid of a N-formyl-L-methionyl-L-leucyl-L-phenylalaninate.

이름 및 식별자

우선 이름: N-Formyl-L-methionyl-L-leucyl-L-phenylalanine
IUPAC: (2S)-2-[[(2S)-2-[[(2S)-2-formamido-4-methylsulfanylbutanoyl]amino]-4-methylpentanoyl]amino]-3-phenylpropanoic acid
현지명: 티라민염화물
영어명: Tyramine hydrochloride
분자식: C21H31N3O5S
분자량: 437.55

이름 및 동의어

59880-97-6fMetLeuPheN-Formyl-L-methionyl-L-leucyl-L-phenylalanineDTXSID9041077CHEBI:53490RefChem:1091810DTXCID00820624N-Formyl-Met-Leu-PheFMLPfMLFN-Formyl-methionyl-leucyl-phenylalaninefMet-Leu-Phe

이름 더 보기

티라민염화물TYRAMINE HCLfMLF, fMLPNSC 350593TYROSAMINE HCLTYRAMINE HCL(P)TYRAMINE HCL(RG)TIMTEC-BB SBB003808N-Formyl-Met-Leu-Phe-OH

Chemotactic peptideF-Met-leu-pheformyl-Met-Leu-PheMFCD00036780(S)-2-((S)-2-((S)-2-Formamido-4-(methylthio)butanamido)-4-methylpentanamido)-3-phenylpropanoic acidFor-Met-Leu-Phe-OHMLS002207097CHEMBL267179

데이터베이스 식별자

CAS: 59880-97-6
PubChem CID: 443295
DTXSID: DTXSID9041077
ChEMBL: CHEMBL267179
ChEBI: CHEBI:53490
UNII: LO6AVJ8RCE
Nikkaji: J245.920E

물성

구조 계산 물성

XLogP: 1.5
극성 표면적: 150 Å²
수소 결합 공여자 수: 4
수소 결합 수용자 수: 6
회전 가능 결합 수: 13
무거운 원자 수: 30
형식 전하: 0
복잡도: 567

물리화학적 성질

녹는점: 271 · 271-274 °C(lit.)
끓는 점: 269 °C · 269 °C
밀도: 1.198 · 1.198±0.06 g/cm3(Predicted)
저장 조건: 2 · 2-8°C
용해도: 50 mg/mL, · DMF: 50mg/mL, 투명, 무색
산도 계수 (pKa): 3.5 · 3.50±0.10(Predicted)
물리적 상태: 백색 내지 황백색의 동결건조된 고체
색상: 흰색에서 거의 흰색
BRN: 2315783 · 2315783
주요 응용: 세포 분석
InChIKey: PRQROPMIIGLWRP-BZSNNMDCSA-N
SMILES: C(O)(=O)[C@H](CC1=CC=CC=C1)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCSC)NC=O

안전 및 규제

안전 데이터

wgk: 3
rtecs: SJ6050000
HS 번호: 2930.90.9250
risk_code: 36/37/38
hazard_code: Xi
safety_code: 26-36-22
F 고인화성물질: 3-10
스토리지 클래스: 11 - Combustible Solids

화학 및 산업

응용 분야

용도Induces leucocyte chemotaxis, and activates macrophages

일반 설명N-Formyl-Met-Leu-Phe is a chemotactin peptide, which functions on polymorphonuclear leukocytes (PMN), neutrophils etc.

공급사50 곳

上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]

湖南韵邦生物科技股份有限公司85561037 15386497078 · [email protected]

上海莉凯化工技术有限公司16628776521 · [email protected]

上海哲研生物科技有限公司021-18017610038 18017610038 · [email protected]

杭州品高化工有限公司0571-87658025 · [email protected]

추가 설명

정의ChEBI: A tripeptide composed of L-Met, L-Leu and L-Phe in a linear sequence with a formyl group at the amino terminus. It acts as a potent inducer of leucocyte chemotaxis and macrophage activator as well as a ligand for the FPR receptor.

연결된 노트

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