기본 정보
- CAS
35115-60-7- 표준 SMILES
CC[C@H](C)[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H]1CCC(=O)N1)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)O- InChIKey
UUUHXMGGBIUAPW-CSCXCSGISA-N- 분자식
- C53H76N14O12
- 평균 분자량
- 1,101.3 g/mol
- 단동위원소 질량
- 1,100.57671391
개요
Teprotide is a peptide.
이름 및 식별자
- 우선 이름
- Teprotide
- IUPAC
- (2S)-1-[(2S)-1-[(2S,3S)-2-[[(2S)-5-amino-2-[[(2S)-1-[(2S)-5-(diaminomethylideneamino)-2-[[(2S)-1-[(2S)-3-(1H-indol-3-yl)-2-[[(2S)-5-oxopyrrolidine-2-carbonyl]amino]propanoyl]pyrrolidine-2-carbonyl]amino]pentanoyl]pyrrolidine-2-carbonyl]amino]-5-oxopentanoyl]amino]-3-methylpentanoyl]pyrrolidine-2-carbonyl]pyrrolidine-2-carboxylic acid
- 영어명
- BPP 9A
- 분자식
- C53H76N14O12
- 분자량
- 1101.26
이름 및 동의어
TEPROTIDE35115-60-7TepromideTeprotidumSQ-20881teprotidaSQ 20881C3E5QBF1R6DTXSID301029698SO-20881Bradykinin potentiator B, 2-L-tryptophan-3-de-L-leucine-4-de-L-proline-8-L-glutamine-BPP-9a
이름 더 보기
DK84DBPP 9APYR-WPRPQIPPBPP 9A USP/EP/BPTeprotide, SQ20881BPP 9a Teprotide, SQ20881Bradykinin potentiator BPP9aBRADYKININ POTENTIATING FACTOR
Bradykinin Potentiating Peptide 9aBradykinin-Potentiating Peptide 9a(2S)-1-((2S)-1-((2S,3S)-2-(((2S)-5-amino-2-(((2S)-1-((2S)-5-guanidino-2-(((2S)-1-((2S)-3-(1H-indol-3-yl)-2-(((2S)-5-oxopyrrolidine-2-carbonyl)amino)propanoyl)pyrrolidine-2-carbonyl)amino)pentanoyl)pyrrolidine-2-carbonyl)amino)-5-oxo-pentanoyl)amino)-3-methyl-pentanoyl)pyrrolidine-2-carbonyl)pyrrolidine-2-carboxylic acid(2S)-1-[(2S)-1-[(2S,3S)-2-[[(2S)-5-amino-2-[[(2S)-1-[(2S)-5-guanidino-2-[[(2S)-1-[(2S)-3-(1H-indol-3-yl)-2-[[(2S)-5-oxopyrrolidine-2-carbonyl]amino]propanoyl]pyrrolidine-2-carbonyl]amino]pentanoyl]pyrrolidine-2-carbonyl]amino]-5-oxo-pentanoyl]amino]-3-methyl-pentanoyl]pyrrolidine-2-carbonyl]pyrrolidine-2-carboxylic acidPeptide 9a, Bradykinin-PotentiatingNonapeptide Converting Enzyme InhibitorNonapeptide-Converting Enzyme InhibitorEnzyme Inhibitor, Nonapeptide-Converting
물성
구조 계산 물성
- XLogP
- -0.9
- 극성 표면적
- 387 Ų
- 수소 결합 공여자 수
- 10
- 수소 결합 수용자 수
- 13
- 회전 가능 결합 수
- 24
- 무거운 원자 수
- 79
- 형식 전하
- 0
- 복잡도
- 2,330
물리화학적 성질
- 밀도
- 1.54 · 1.54±0.1 g/cm3(Predicted)
- 저장 조건
- -20 °C · -20°C
- 용해도
- 1 mg/mL, · water: soluble 1 mg/mL, clear, colorless
- 산도 계수 (pKa)
- 3.44 · 3.44±0.20(Predicted)
- 물리적 상태
- 가루
- 생물학적 소스
- synthetic (organic)
- 수용성
- 1 mg/mL, · water: soluble 1mg/mL, clear, colorless
- InChIKey
- UUUHXMGGBIUAPW-CSCXCSGISA-N
안전 및 규제
안전 정보는 참고용이며, 공급업체의 물질안전보건자료(SDS), 관련 법규 및 전문가 평가를 대체하지 않습니다.
안전 데이터
- wgk
- 3
- 스토리지 클래스
- 11 - Combustible Solids
화학 및 산업
약리 정보
MeSH Pharmacological Classification
A class of drugs whose main indications are the treatment of hypertension and heart failure. They exert their hemodynamic effect mainly by inhibiting the renin-angiotensin system. They also modulate sympathetic nervous system activity and increase prostaglandin synthesis. They cause mainly vasodilation and mild natriuresis without affecting heart rate and contractility.
Drugs used in the treatment of acute or chronic vascular HYPERTENSION regardless of pharmacological mechanism. Among the antihypertensive agents are DIURETICS; (especially DIURETICS, THIAZIDE); ADRENERGIC BETA-ANTAGONISTS; ADRENERGIC ALPHA-ANTAGONISTS; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; CALCIUM CHANNEL BLOCKERS; GANGLIONIC BLOCKERS; and VASODILATOR AGENTS.
공급사83 곳
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
上海麦克林生化科技股份有限公司021-50706066 15221275939 · [email protected]
江苏艾康生物医药研发有限公司025-58851090 19370895928 · [email protected]
上海哲研生物科技有限公司021-18017610038 18017610038 · [email protected]
上海优宁维生物科技股份有限公司15921930842 15921930842 · [email protected]
Hangzhou Go Top Peptide Biotech0571-88211921 · [email protected]
南京昱盛康生物科技有限公司13327808530 · [email protected]
Hebei Yanxi Chemical Co., Ltd.+86-17531190177 · [email protected]
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