(-)-췌장

개요This alkaloid occurs in Narcissus poeticus, Pancratium maritium and Rhodo_x0002_phiala bifida. It yields long, colourless prisms when recrystallized from MeOH and is laevorotatory with [α]25D - 74° (c 0.02, MeOH). The ultraviolet spectrum has two absorption maxima at 241 and 292 mil. It yields a crystalline perchlorate, m.p. 163-6°C and a picrate, m.p. 249-2S2°C. Two non-phenolic hydroxyl groups and one methylenedioxy group are present in the molecule. The 2-a-O-acetate is an amorphous solid which cannot be obtained crystalline but the 3-{3-0-acetate forms colourless crystals from MeOH, m.p. 213-6°C. The O,O-diacetate, also crystalline, has m.p. 163-S°C. The O-methyl derivatives occur naturally, the 2-methyl compound is Montanine (q.v.) and the 2:3-dimethyl ether is Manthine (q.v.). The structure is based primarily upon the mass spectrum fragmentation pattern.