Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
(-)-장뇌
(-)-장뇌 · Bicyclo[2.2.1]heptan-2-one, 1,7,7-trimethyl-, (1S)- · CAMPHORE · (-)-Alcanfor · Camphor Camphor · Levo-(-)-camphor · (1S)-(-)-Camphor 95% · (1S)-1,7,7-TRIMETHYLBICYCLO[2.2.1]HEPTAN-2-ONE
식별자 및 물리적 특성
| CAS No. | 464-48-2 |
|---|---|
| 분자식 | C10H16O |
| 평균 분자량 | 152.23 g/mol |
| 단동위원소 질량 | 152.12011513 g/mol |
| SMILES | CC1(C)[C@H]2CC[C@]1(C)C(=O)C2 |
| InChIKey | DSSYKIVIOFKYAU-OIBJUYFYSA-N |
| PubChem CID | 444294 |
| ChEMBL | CHEMBL2252949 |
| ChEBI | CHEBI:15397 |
| EC No. | 207-354-7 |
| DTXSID | DTXSID8022036 |
| 현지명 | (-)-장뇌 |
화학 및 물리적 성질
| XLogP | 2.2 |
|---|---|
| 극성 표면적 | 17.1 |
| 수소 결합 공여자 수 | 0 |
| 수소 결합 수용자 수 | 1 |
| 회전 가능 결합 수 | 0 |
| 무거운 원자 수 | 11 |
| 형식 전하 | 0 |
| 복잡도 | 217 |
| 물질 분류 | Biological Agents -> Plant Oils and Extracts |
| 밀도 | 0.992 at 77 °F (NTP, 1992) - Less dense than waterwill float0.990 |
| 용해도 | 1 g/800 mL at 77 °F (NTP, 1992)DMF: 30 mg/mlDMSO: 20 mg/mlEthanol: 30 mg/mlEthanol:PBS (pH 7.2)(1:2): 0.33 mg/ml |
| 인화점 | 150 °F (NTP, 1992)148 °F |
| 끓는 점 | 399 °F at 760 mmHg (sublimes) (NTP, 1992)204 °C(lit.) |
| 녹는점 | 353.5 °F (NTP, 1992)178-180177-179 °C(lit.) |
| 증기 밀도 | 5.24 (NTP, 1992) - Heavier than airwill sink (Relative to Air)5.24 (vs air) |
| 증기압 | 1 mmHg at 106.7 °F (NTP, 1992)0.18 [mmHg]4 mm Hg ( 70 °C) |
| Physical Description | L-camphor appears as colorless or white crystals. Fragrant and penetrating odor. Slightly bitter and cooling taste. Odor index at 68 °F: 40. Flash point 149 °F. Burns with a bright, smoky flame. Sublimes appreciably at room temperature and pressure14% sublimes within 60 minutes at 176 °F and 12 mmHg. (NTP, 1992)Colorless to white solid with a strong fragrant odor[CAMEO] White powder[Sigma-Aldrich MSDS] |
| 자연 발화 온도 | 871 °F (NTP, 1992) |
| 굴절률 | -44 ° (C=20, EtOH) |
| 저장 조건 | Sealed in dry,Room Temperature |
| 물리적 상태 | 결정 또는 결정성 분말 부착 |
| 색상 | 흰색에서 노란색으로 |
| 비중 | 0.9853 (18℃) |
| 냄새 | 디프로필렌 글리콜 중 10.00%. 장뇌 |
| 향취 유형 | 녹나무 같은 |
| 폭발한계 | 0.6-4.5%(V) |
| 용해도 | 물에 용해됩니다. (0.34g/L), 20°C에서 |
| Merck | 14,1732 |
| BRN | 4291747 |
| 안정성 | 안정적인. 강한 환원제, 강한 산화제, 염소계 용제와 호환되지 않습니다. 직사광선으로부터 보호하세요. |
| InChI | 1S/C10H16O/c1-9(2)7-4-5-10(9,3)8(11)6-7/h7H,4-6H2,1-3H3/t7-,10+/m0/s1 |
| InChIKey | DSSYKIVIOFKYAU-OIBJUYFYSA-N |
| SMILES | [H][C@]12CC[C@](C)(C(=O)C1)C2(C)C |
| LogP(분배 계수) | 2.089 (est) |
| EPA | l-Camphor (464-48-2) |
화학적 성질
white crystals
안전 및 규제
| GHS 분류 | DangerH228 (35.5%): Flammable solid [Danger Flammable solids]P203, P210, P240, P241, P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P318, P319, P321, P332+P317, P337+P317, P362+P364, P370+P378, P403+P233, P405, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 138 reports by companies from 10 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies. |
|---|---|
| 규제 정보 | Chemical: Bicyclo[2.2.1]heptan-2-one, 1,7,7-trimethyl-, (1S)-(1S)-(-)-Camphor: Does not have an individual approval but may be used under an appropriate group standard |
| 기타 안전 정보 | IMAP assessments - Bicyclo[2.2.1]heptan-2-one, 1,7,7-trimethyl-, (1S)-: Environment tier I assessment |
| 운송 라벨(DOT) | Flammable Solid |
| 화재 위험 | This chemical is flammable. (NTP, 1992) |
| 건강 유해성 | SYMPTOMS: Ingestion of this compound may cause nausea, vomiting, vertigo, mental confusion, delirium, convulsions, coma, respiratory failure or death. It may also cause a burning sensation, coughing, wheezing, laryngitis, shortness of breath, headache, severe irritation and possible destruction to the tissues of the mucous membranes, upper respiratory tract, eyes and skin. Other symptoms may include congestion and edematous changes in the gastrointestinal tract, kidneys and brain. Ingestion may result in burning in the mouth and throat, epigastric pain, thirst, feeling of tension, dizziness, irrational behavior, unconsciousness, rigidity, rapid pulse, slow respiration, twitching of the facial muscles and muscular spasms. Other symptoms may include flickering, darkening or veiling of vision, noises in the ears and weakness. Exposure to this compound may also result in a feeling of warmth, depression of the central nervous system, difficult breathing, a characteristic breath odor and anuria. Colic may also be a symptom of exposure. Other symptoms may include eye irritation, sore throat, excitement, fever, bluish lips, pale face, loss of sense of smell and agitation. |
| 유해성 요약 | May cause severe skin, eye, mucous membrane, and upper respiratory tract irritationMay cause CNS depression and other nervous system effectsHarmful by ingestion, inhalation, and skin absorption[NTP] Causes convulsions in oral lethal-dose studies of rats |
용도
용도
(1S)-(-)-Camphor is used as chiral intermediate and chiral auxiliary precursor. It is used in the synthesis of high-potency sweeteners. It acts as catalytic agent and petrochemical additive.
일반 설명
Colorless or white crystals. Fragrant and penetrating odor. Slightly bitter and cooling taste. Odor index at 68°F: 40. Flash point 149°F. Burns with a bright, smoky flame. Sublimes appreciably at room temperature and pressure; 14% sublimes within 60 minutes at 176°F and 12 mm Hg.