키틴

O-2-(Acetylamino)-2-deoxy-beta-D-glucopyranosyl-(1->4)-O-2-(acetylamino)-2-deoxy-beta-D-glucopyranosyl-(1->4)-2-(acetylamino)-2-deoxy-beta-D-glucopyranose

HCID 444514

기본 정보

CAS
13319-32-9
표준 SMILES
CC(=O)N[C@@H]1[C@@H](O)[C@H](O[C@@H]2O[C@H](CO)[C@@H](O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3NC(C)=O)[C@H](O)[C@H]2NC(C)=O)[C@@H](CO)O[C@H]1O
InChIKey
WZZVUHWLNMNWLW-VFCSDQTKSA-N
분자식
C24H41N3O16
평균 분자량
627.6 g/mol
단동위원소 질량
627.24868223

개요

Beta-D-GlcpNAc-(1->4)-beta-D-GlcpNAc-(1->4)-beta-D-GlcpNAc is a linear amino trisaccharide consisting of three N-acetyl-beta-D-glucosamine residues linked (14). It has a role as an epitope.

이름 및 식별자

우선 이름
O-2-(Acetylamino)-2-deoxy-beta-D-glucopyranosyl-(1->4)-O-2-(acetylamino)-2-deoxy-beta-D-glucopyranosyl-(1->4)-2-(acetylamino)-2-deoxy-beta-D-glucopyranose
IUPAC
N-[(2R,3R,4R,5S,6R)-5-[(2S,3R,4R,5S,6R)-3-acetamido-5-[(2S,3R,4R,5S,6R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-4-hydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-2,4-dihydroxy-6-(hydroxymethyl)oxan-3-yl]acetamide
현지명
키틴
영어명
Chitin
분자식
C6H11NO4X2
분자량
161.16

이름 및 동의어

13319-32-9DTXSID801100881GlyTouCan:G47362BJRefChem:1048464DTXCID201532583G47362BJO-2-(Acetylamino)-2-deoxy-beta-D-glucopyranosyl-(1->4)-O-2-(acetylamino)-2-deoxy-beta-D-glucopyranosyl-(1->4)-2-(acetylamino)-2-deoxy-beta-D-glucopyranoseTRIACETYLCHITOTRIOSEbeta-N,N',N''-triacetylchitotrioseN,N',N''-triacetyl chitotriose beta-anomerCHEBI:71404beta-D-GlcpNAc-(1->4)-beta-D-GlcpNAc-(1->4)-beta-D-GlcpNAc
이름 더 보기
키틴DEACETYLATED CHITINa-chitinChitin-13CXChitin (powder)SQUID PEN CHITINColloidal ChitinCHITINMICROPARTICLESPOLY-N-ACETYLGLUCOSAMINECHITIN FROM SHRIMP SHELLSBETA-(1,4)-2-ACETAMIDO-2-DEOXY-D-GLUCOSE
GlcNAcbeta1-4GlcNAcbeta1-4GlcNAcbeta(beta)-N,N',N''-triacetyl chitotriosebeta-D-GlcNAc-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc2-acetamido-2-deoxy-beta-D-glucopyranosyl-(1->4)-2-acetamido-2-deoxy-beta-D-glucopyranosyl-(1->4)-2-acetamido-2-deoxy-beta-D-glucopyranoseN-acetyl-beta-D-glucosaminyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->4)-N-acetyl-beta-D-glucosamine1at51at62r0h

데이터베이스 식별자

CAS
13319-32-9、1398-61-4
PubChem CID
444514
DTXSID
DTXSID801100881
ChEMBL
CHEMBL1222017
ChEBI
CHEBI:71404
UNII
ALA7M3MVL3
Nikkaji
J419.926J

물성

구조 계산 물성

XLogP
-6.9
극성 표면적
295 Ų
수소 결합 공여자 수
11
수소 결합 수용자 수
16
회전 가능 결합 수
10
무거운 원자 수
43

실험 및 물리화학적 성질

DrugsPharmaceuticals -> Listed in ZINC15
Physical DescriptionSolid

물리화학적 성질

녹는점
300 °C · >300°C (dec.)
끓는 점
737.18 °C · 737.18°C (rough estimate)
밀도
1.3744 · 1.3744 (rough estimate)
굴절률
1.6 · 1.6000 (estimate)
저장 조건
Room Temp
용해도
묽은 수성 산(pH <6.5): 가용성
화학적 성질 · 1건

Chitin is a colorless, crystalline or amorphous powder that is insoluble in water, organic solvents, dilute acids, and alkalis. It dissolves in concentrated mineral acids with simultaneous degradation of the polymer. Although chitosan is insoluble in water, it does dissolve in aqueous organic acids, for example, acetic and formic acids, as well as inorganic acids. Chitin and chitosan preparation can vary due to the source, with compositional differences. Similarly, the physicochemical characteristics of chitin and chitosan differ between crustacean species and preparation methods. Several studies have clearly demonstrated the specific characteristics of these products. The Mw and degree of deacetylation (DD) vary with process conditions. The physicochemical characteristics of chitin and chitosan influence their functional properties. Mw and DD vary with process conditions or different extraction methods. Chitosan's application depends on physical, biological, and chemical properties and chitosan depends on two parameters, such as DD and Mw.

안전 및 규제

안전 데이터

wgk
3
tsca
TSCA listed
rtecs
FM6300000
HS 번호
32139000
risk_code
20/21/22-36/37/38
hazard_code
Xi,Xn

화학 및 산업

약리 정보

Tissue LocationsFibroblasts
Cellular LocationsExtracellular
Metabolite Pathways2-Hydroxyglutric Aciduria (D And L Form)
응용 분야 · 2건

개요Chitin is the most abundant natural amino polysaccharide. It has a similar annual yield as cellulose. Chitin is a kind of highly valuable material in biomedical applications because of its high biocompatibility, biodegradability and non-toxicity as well as its antimicrobial activity and low immunogenicity. It can be easily processed into gels, membrane, nanofibers, beads, nanoparticle, scaffold and sponges, enables its wide applications. In the tissue engineering, it can be used for manufacturing polymer scaffold to satisfy the demands of repairing, replacing, maintaining, or enhancing the function of a particular tissue or organ. In wound dressing, chitin can be used as antimicrobial reagent. In the field of drug delivery, the water-soluble carboxymethyl chitin (CMC) nanoparticle can be used as an effective carrier in drug delivery.

용도chitin (chitine) is a moisture retainer and film-forming agent. This is a naturally occurring polysaccharide found in the shells of crustaceans, such as shrimp and crab, as well as in some fungi and algae. It is also a naturally occuring fibre found in the shells of shellfish. Used for the analysis of chitinase. lysozyme substrate.

공급사100 곳

北京华美互利生物化工010-56205725 · [email protected]
梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
上海如吉生物科技发展有限公司+86-21-65211385-8001 36031160 · [email protected]
陕西瑞林帕尼尔生物科技有限公司029-86107037-8019 15332321378 · [email protected]
추가 설명 · 4건

정의이 품목은 게, 새우 등의 갑각류 껍질 또는 오징어의 뼈를 산성수용액에서 탄산칼슘을 제거한 후 약알칼리성수용액으로 단백질을 제거한 것으로서 주성분은 N-아세틸글루코사민(N-acetyl- glucosamine) 다량체이다. 성 상 이 품목은 백~엷은 황색 또는 적색을 띠는 분말 혹은 비늘모양 고체로서 약간 특유의 냄새가 있다.

순도시험(1) 비소 : 이 품목을 비소시험법에 따라 시험할 때, 그 양은 4.0ppm 이하이어야 한다. (2) 납 : 이 품목 5.0g을 취하여 원자흡광광도법 또는 유도결합플라즈마발광광도법에 따라 시험할 때, 그 양은 2.0ppm 이하이어야 한다.

확인시험이 품목 0.2g에 안트론시액 5mL 및 물 1mL를 가하여 수욕상에서 가열할 때, 액은 청~녹색을 나타낸다.

정의ChEBI: Chitin is a polysaccharide comprisingchains of N-acetyl-d-glucosamine,a derivative of glucose. Chitin isstructurally very similar to celluloseand serves to strengthen the supportingstructures of various invertebrates. It is the second most abundant biopolymer on earth, found especially in insects and fungi.

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