Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용

HCID 446596생성일: 2026년 10월 27일

Mupirocin

MUPIROCIN CALCIUM · 231-791-2 · PSEUDOMONIC ACID · PSEUDOMONIC ACID A · bactroban · L-talo-Non-2-enonic acid, 5,9-anhydro-2,3,4,8-tetradeoxy-8-(2S,3S)-3-(1S,2S)-2-hydroxy-1-methylpropyloxiranylmethyl-3-methyl-, 8-carboxyoctyl ester, (2E)- · Turixi · Turixin

https://huagongshe.com/ko/chemical/446596

식별자 및 물리적 특성

CAS No.	12650-69-0
분자식	C26H44O9
평균 분자량	500.6 g/mol
단동위원소 질량	500.29853299 g/mol
SMILES	C/C(=C\C(=O)OCCCCCCCCC(=O)O)C[C@@H]1OC[C@H](C[C@@H]2O[C@H]2[C@@H](C)[C@H](C)O)[C@@H](O)[C@H]1O
InChIKey	MINDHVHHQZYEEK-HBBNESRFSA-N
PubChem CID	446596
ChEMBL	CHEMBL719
ChEBI	CHEBI:7025
EC No.	603-145-3
DTXSID	DTXSID0046438

화학 및 물리적 성질

XLogP	3
극성 표면적	146
수소 결합 공여자 수	4
수소 결합 수용자 수	9
회전 가능 결합 수	17
무거운 원자 수	35
형식 전하	0
복잡도	694
의약품	Pharmaceuticals -> Listed in ZINC15Pharmaceuticals -> Antibiotics
용해도	2.65e-02 g/LH2O: 12 mg/mL, 가용성
Human Drugs	Breast FeedingLactationMilk, HumanAnti-Infective Agents, LocalAntibacterial AgentsFDA approved drugs -> Active ingredientDermatological medicines > Anti-infective medicines
Animal Drugs	Active Ingredients (Mupirocin) -> FDA Greenbook
녹는점	77-7877 - 78 °C77-780C
Physical Description	Solid
Collision Cross Section	215.12 Å² [M+Na]+ [CCS Type: TWMethod: calibrated with polyalanine and drug standards]214.8 Å² [M+H]+ [CCS Type: TW
끓는 점	672℃
밀도	1.183±0.06 g/cm3(Predicted)
인화점	>110°(230°F)
저장 조건	Inert atmosphere,Store in freezer, under -20°C
물리적 상태	고체
pKa(산도 계수)	4.78±0.10(Predicted)
색상	흰색에서 황갈색까지
용해도	DMSO 또는 메탄올에 용해됩니다. 물에 거의 녹지 않음
Merck	14,6302
안정성	제공된 대로 구매일로부터 1년 동안 안정적입니다. DMSO의 솔루션은 -20°C에서 최대 1개월 동안 보관할 수 있습니다.
주요 응용	제약
InChIKey	MINDHVHHQZYEEK-HBBNESRFSA-N
SMILES	[H][C@@]1(CO[C@@H](C\C(C)=C\C(=O)OCCCCCCCCC(O)=O)[C@H](O)[C@@H]1O)C[C@@H]2O[C@@]2([H])[C@@H](C)[C@H](C)O

화학적 성질

White Crystalline Solid

안전 및 규제

GHS 분류	This chemical does not meet GHS hazard criteria for 25% (1 of 4) of reports.WarningH302 (25%): Harmful if swallowed [Warning Acute toxicity, oral]P261, P264, P264+P265, P270, P272, P280, P301+P317, P302+P352, P305+P351+P338, P321, P330, P332+P317, P333+P317, P337+P317, P362+P364, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 4 reports by companies from 4 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
규제 정보	Mupirocin: Does not have an individual approval but may be used under an appropriate group standard
Hazard Classes and Categories	Acute Tox. 4 (25%)
유해 작용	Adverse Drug Reactions
독성 요약	Currently, no available study or report suggests that using topical mupirocin consistently causes systemic toxicity. As previously stated, caution is advised in individuals with severe renal impairment and those with large open wounds due to the potential for increased absorption and nephrotoxicity. In such cases, renal function should be closely monitored with scheduled renal function panels, as stated in the FDA guidelines for Bactroban.
Effects During Pregnancy and Lactation	◉ Summary of Use during Lactation
수질 위해 등급(WGK)	2
RTECS 번호	RA6907000
관세 코드	2941906000
저장 분류	11 - Combustible Solids

용도

개요

Mupirocin (pseudomonic acid A) is an antibiotic produced by Pseudomonas fluorescens. It is useful in the treatment of dermal infections, especially those involving S. aureus and S. epidermidis.

용도

Mupirocin, is a major component of the pseudomonic acid, an antibiotic complex produced by Pseudomonas fluorescens NCIB 10586. Topical antibacterial.

Mupirocin

식별자 및 물리적 특성

CAS No.

12650-69-0

분자식

C26H44O9

평균 분자량

500.6 g/mol

단동위원소 질량

500.29853299 g/mol

SMILES

C/C(=C\C(=O)OCCCCCCCCC(=O)O)C[C@@H]1OC[C@H](C[C@@H]2O[C@H]2[C@@H](C)[C@H](C)O)[C@@H](O)[C@H]1O

InChIKey

MINDHVHHQZYEEK-HBBNESRFSA-N

PubChem CID

446596

ChEMBL

CHEMBL719

ChEBI

CHEBI:7025

EC No.

603-145-3

DTXSID

DTXSID0046438

화학 및 물리적 성질

XLogP

극성 표면적

146

수소 결합 공여자 수

수소 결합 수용자 수

회전 가능 결합 수

무거운 원자 수

형식 전하

복잡도

694

의약품

Pharmaceuticals -> Listed in ZINC15Pharmaceuticals -> Antibiotics

용해도

2.65e-02 g/LH2O: 12 mg/mL, 가용성

Human Drugs

Breast FeedingLactationMilk, HumanAnti-Infective Agents, LocalAntibacterial AgentsFDA approved drugs -> Active ingredientDermatological medicines > Anti-infective medicines

Animal Drugs

Active Ingredients (Mupirocin) -> FDA Greenbook

녹는점

77-7877 - 78 °C77-780C

Physical Description

Solid

Collision Cross Section

215.12 Å² [M+Na]+ [CCS Type: TWMethod: calibrated with polyalanine and drug standards]214.8 Å² [M+H]+ [CCS Type: TW

끓는 점

672℃

밀도

1.183±0.06 g/cm3(Predicted)

인화점

>110°(230°F)

저장 조건

Inert atmosphere,Store in freezer, under -20°C

물리적 상태

고체

pKa(산도 계수)

4.78±0.10(Predicted)

색상

흰색에서 황갈색까지

용해도

DMSO 또는 메탄올에 용해됩니다. 물에 거의 녹지 않음

Merck

14,6302

안정성

제공된 대로 구매일로부터 1년 동안 안정적입니다. DMSO의 솔루션은 -20°C에서 최대 1개월 동안 보관할 수 있습니다.

주요 응용

제약

InChIKey

MINDHVHHQZYEEK-HBBNESRFSA-N

SMILES

[H][C@@]1(CO[C@@H](C\C(C)=C\C(=O)OCCCCCCCCC(O)=O)[C@H](O)[C@@H]1O)C[C@@H]2O[C@@]2([H])[C@@H](C)[C@H](C)O

화학적 성질

White Crystalline Solid

안전 및 규제

GHS 분류

This chemical does not meet GHS hazard criteria for 25% (1 of 4) of reports.WarningH302 (25%): Harmful if swallowed [Warning Acute toxicity, oral]P261, P264, P264+P265, P270, P272, P280, P301+P317, P302+P352, P305+P351+P338, P321, P330, P332+P317, P333+P317, P337+P317, P362+P364, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 4 reports by companies from 4 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

규제 정보

Mupirocin: Does not have an individual approval but may be used under an appropriate group standard

Hazard Classes and Categories

Acute Tox. 4 (25%)

유해 작용

Adverse Drug Reactions

독성 요약

Currently, no available study or report suggests that using topical mupirocin consistently causes systemic toxicity. As previously stated, caution is advised in individuals with severe renal impairment and those with large open wounds due to the potential for increased absorption and nephrotoxicity. In such cases, renal function should be closely monitored with scheduled renal function panels, as stated in the FDA guidelines for Bactroban.

Effects During Pregnancy and Lactation

◉ Summary of Use during Lactation

수질 위해 등급(WGK)

RTECS 번호

RA6907000

관세 코드

2941906000

저장 분류

11 - Combustible Solids

용도

개요

Mupirocin (pseudomonic acid A) is an antibiotic produced by Pseudomonas fluorescens. It is useful in the treatment of dermal infections, especially those involving S. aureus and S. epidermidis.

용도

Mupirocin, is a major component of the pseudomonic acid, an antibiotic complex produced by Pseudomonas fluorescens NCIB 10586. Topical antibacterial.