기본 정보
- CAS
63758-79-2- 표준 SMILES
c1ccc2c(CCC3CCNCC3)c[nH]c2c1- InChIKey
SADQVAVFGNTEOD-UHFFFAOYSA-N- 분자식
- C15H20N2
- 평균 분자량
- 228.33 g/mol
- 단동위원소 질량
- 228.16264865
개요
Indalpine is a member of indoles.
이름 및 식별자
- 우선 이름
- Indalpine
- IUPAC
- 3-(2-piperidin-4-ylethyl)-1H-indole
- 현지명
- 3-(2-(PIPERIDIN-4-YL)에틸)-1H-인돌
- 영어명
- Indalpine
- 분자식
- C15H20N2
- 분자량
- 228.33
이름 및 동의어
INDALPINE63758-79-23-(2-(Piperidin-4-yl)ethyl)-1H-indoleIndalpinumindalpina4-[2-(3-indolyl)ethyl]piperidineV35562QSVTDTXSID802131961H-Indole, 3-(2-(4-piperidinyl)ethyl)-4-(2-(3-indolyl)ethyl)piperidine3-[2-(piperidin-4-yl)ethyl]-1H-indole(3-indolyl-2-ethyl)piperidine
이름 더 보기
3-(2-(PIPERIDIN-4-YL)에틸)-1H-인돌UpsteneLM-5008Indalpino3-(2-(4-piperidyl)ethyl)-indol3-(2-(4-piperidinyl)ethyl)-1h-indol3-[2-(4-Piperidinyl)ethyl]-1H-indole1H-Indole, 3-[2-(4-piperidinyl)ethyl]-
RefChem:148093DTXCID80135687264-445-43-(2-piperidin-4-ylethyl)-1H-indoleLM 5008Lipstene3-(2-(4-Piperidyl)ethyl)indoleCHEMBL276520
데이터베이스 식별자
- CAS
63758-79-2- PubChem CID
- 44668
- DTXSID
물성
구조 계산 물성
- XLogP
- 3.3
- 극성 표면적
- 27.8 Ų
- 수소 결합 공여자 수
- 2
- 수소 결합 수용자 수
- 1
- 회전 가능 결합 수
- 3
- 무거운 원자 수
- 17
- 형식 전하
- 0
- 복잡도
- 235
실험 및 물리화학적 성질
DrugsPharmaceuticals -> Listed in ZINC15
안전 및 규제
안전 정보는 참고용이며, 공급업체의 물질안전보건자료(SDS), 관련 법규 및 전문가 평가를 대체하지 않습니다.
안전 데이터
- ridadr
- 3249
- 포장분류
- III
- 위험 등급
- 6.1(b)
화학 및 산업
약리 정보
MeSH Pharmacological Classification
Mood-stimulating drugs used primarily in the treatment of affective disorders and related conditions. Several MONOAMINE OXIDASE INHIBITORS are useful as antidepressants apparently as a long-term consequence of their modulation of catecholamine levels. The tricyclic compounds useful as antidepressive agents (ANTIDEPRESSIVE AGENTS, TRICYCLIC) also appear to act through brain catecholamine systems. A third group (ANTIDEPRESSIVE AGENTS, SECOND-GENERATION) is a diverse group of drugs including some that act specifically on serotonergic systems.
Compounds that specifically inhibit the reuptake of serotonin in the brain.
응용 분야
개요Indalpine is a non-tricyclic antidepressant with a serotonin selective profile. It is 6-7 times more potent than fluoxetine and clomipramine in inhibiting serotonin reuptake in vitro in rat brain synaptosomes. Statistically significant clinical effects within one week of onset of treatment have been reported. An anxiolytic effect may accompany the antidepressant effect. Indalpine appears devoid of anticholinergic and cardiovascular side effects and does not promote weight gain or affect appetite.
공급사11 곳
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