홈MCP워크벤치Skills
홈워크벤치알림마이페이지
Huagongshe 오픈 프로젝트:[email protected]AI 접속: llms.txt · MCP 가이드개인정보처리방침 · 이용약관 · 지원v1.7.8
  1. 홈
  2. /화합물

니트로 글리세린

Trinitroglycerin

HCID 4510
노트반응

데이터를 보충하는 중입니다. 잠시 후 페이지를 새로 고치면 최신 내용을 볼 수 있습니다

기본 정보이름 및 식별자물성안전 및 규제화학 및 산업관련 반응화합물 노트
부분 구조 검색유사 구조 찾기

기본 정보

CAS
55-63-0
표준 SMILES
O=[N+]([O-])OCC(CO[N+](=O)[O-])O[N+](=O)[O-]
InChIKey
SNIOPGDIGTZGOP-UHFFFAOYSA-N
분자식
C3H5N3O9
평균 분자량
227.085 g/mol
단동위원소 질량
227.00257874

이름 및 식별자

우선 이름
Trinitroglycerin
IUPAC
Propane-1,2,3-triyl trinitrate
현지명
니트로 글리세린
영어명
Nitroglycerin
분자식
C3H5N3O9
분자량
227.09

이름 및 동의어

니트로글리세린나이트로글리세린나이트로글리콜질산그리세롤나이트로글리세린,1%미만의나이트로글리세린이함유된알코올용액프로판-1,2,3-트라일트라이나이트레이트1,2,3-프로페인트라이올 트라이나이트레이트1,2,3-프로페인트라이올, 1,2,3-트라이나이트레이트1,2,3-프로페인트라이올, 트라이나이트레이트1,3-다이나이트옥시프로판-2-일 나이트레이트글리세롤 트라이나이트레이트글리세린 트라이나이트레이트
이름 더 보기
글리세릴 트라이나이트레이트나이트로글리세린, 1% 미만의 나이트로글리세린이 함유된 알코올 용액Glyceryl trinitrateNITROGLYCERINENTGDiluted NitroglycerinTNGGTNNitrolingualNitroglicerinaSNGNitrol

데이터베이스 식별자

CAS
55-63-0
PubChem CID
4510
DTXSID
DTXSID1021407
ChEMBL
CHEMBL730
ChEBI
CHEBI:28787
UNII
G59M7S0WS3
EC Number
200-240-8
Nikkaji
J4.491A

물성

물리화학적 성질

녹는점
2.8 °; · 2.8°; mp 13.5°
끓는 점
368.78 °C · 368.78°C (rough estimate)
밀도
1515 · d1515 1.599; d44 1.6144; d415 1.6009; d425 1.5918
굴절률
15 · nD15 1.474
인화점
12 °C · 12°C
저장 조건
-20 °C · -20°C
용해도
아세톤 및 무수 에탄올과 혼합 가능
물리적 상태
액체
수용성
1.25 g/L · 1.25g/L(25℃)
비열
1.03 J/ · Cp(gas): 1.03 J/(g·K), at 25℃
Henry's Law Constant
2.3 · 2.3×102 mol/(m3Pa) at 25℃, HSDB (2015)
Dielectric constant
19 · 19.0(20℃)
BCS Class
1 · 1
주요 응용
의약품(소분자)
InChI
1S/C3H5N3O9/c7-4(8)13-1-3(15-6(11)12)2-14-5(9)10/h3H,1-2H2
InChIKey
SNIOPGDIGTZGOP-UHFFFAOYSA-N
SMILES
O=[N+]([O-])OCC(CO[N+]([O-])=O)O[N+]([O-])=O
NIST
1 · 1,2,3-Propanetriol, trinitrate(55-63-0)
EPA
Nitroglycerin (55-63-0)

화학적 성질

Nitroglycerin is a pale yellow liquid or crystalline solid (below 13℃).

안전 및 규제

안전 정보는 참고용이며, 공급업체의 물질안전보건자료(SDS), 관련 법규 및 전문가 평가를 대체하지 않습니다.

안전 데이터

OEL
STEL: 0.1 mg/m3 [skin]
wgk
3
IDLA
75 mg/m3
tsca
TSCA listed
ridadr
UN 3064 3/PG II (NITROGLYCERIN, SOLUTION IN ALCOHOL with more than 1 % but not more than 5 % nitroglycerin)
독성
LD50 oral in rabbit: 1607mg/kg
HS 번호
2920900002
risk_code
11-51/53-33-26/27/28-3-36-20/21/22-23/24/25
hazard_code
E,T+,N,Xn,T
safety_code
7-16-61-45-36/37-35-33-26
포장분류
I
위험 등급
1.1A
기존화학 물질
KE-25998
Hazard Classifications
Acute Tox. 3 DermalAcute Tox. 4 OralFlam. Liq. 2
스토리지 클래스
3 - Flammable liquids
유해 물질 데이터
55-63-0(Hazardous Substances Data)

화학 및 산업

응용 분야 · 4건

개요Nitroglycerin is an oily, poisonous, clear to pale yellow, explosive liquid.Nitroglycerin is made by nitrating glycerol. Early industrial processes used a batch process in which glycerol was added to a mixture with approximately equal volumes of nitric acid and sulfuric acid.The sulfuric acid serves to ionize the nitric acid and removes water formed in the nitration process.

역사It was first prepared in 1846 by the Italian chemist Ascanio Sobrero (1812–1888), who nitrated glycerol using a mixture of nitric acid and sulfuric acid. Sobrero, who was injured in an explosion doing his research, realized the compound’s danger and abandoned work on nitroglycerin. Twenty years after Sobrero’s discovery, Alfred Nobel (1833–1896) developed its use commercially. Nobel mixed nitroglycerin with other substances, searching for a safe way to transport it and make it less sensitive to heat and pressure.nitroglycerin when it was first marketed,and Nobel continued to experiment with methods to make nitroglycerin safer.One of these was mixing nitroglycerin with materials to make a solid form of nitroglycerin. Nobel discovered that when nitroglycerin was mixed with a silica-based diatomaceous earth material called kieselguhr,a relatively stable product resulted.The mixture produced a paste that Nobel could pack into cardboard tubes;these could then be inserted into holes drilled into rock structures and detonated.In 1867,Nobel patented his mixture and called it dynamite,a name derived from the Greek word dunamis, meaning power.Nobel also perfected a blasting cap made from mercury fulminate (Hg(ONC)2) and potassium chlorate (KClO3) to detonate the nitroglycerin.

용도Nitroglycerin has medicinal use as a vasodilator. The main medical use of nitroglycerin is to treat angina pectoris. Nitroglycerin was first used to treat this condition in the late 19th century. It is prescribed today in various forms (tablet, ointment, patches, and injection) for patients who suffer from angina pectoris. Nitroglycerin is marketed under various trade names: Nitro-Dur, Nitrostat, Nitrospan, Nitro-Bid, and Tridil. When used in medications, the name glyceryl trinitrate is often used instead of nitroglycerin.

일반 설명Colorless to pale-yellow, viscous liquid or solid (below 56°F). (Note: An explosive ingredient in dynamite (20-40%) with ethylene glycol dinitrate (80-60%).).

제조 방법 · 1건

관련 반응

1건
반응 기록 만들기
HRID 1156505 반응식
HRID 1156505생성물로uspto-grants-1982_06

화합물 노트

불러오는 중…

이 페이지에서기본 정보이름 및 식별자물성안전 및 규제화학 및 산업관련 반응화합물 노트

생산 방법Nitroglycerin is made by nitrating glycerol.Early industrial processes used a batch processin which glycerol was added to a mixture with approximately equal volumes of nitric acidand sulfuric acid.The sulfuric acid serves to ionize the nitric acid and removes water formedin the nitration process.Removing the water formed in nitration increases the yield of nitroglycerin.Acids and water must be removed from the desired nitroglycerin through a washingprocess. The production of nitroglycerin is highly exothermic,and it is important to keepthe temperature below room temperature to prevent an explosion. Early production methodsused cooling coils in the nitration vessels to regulate the temperature.During the latter halfof the 20th century, safer continuous production methods replaced batch processes.In thesemethods much smaller reactors are required,as glycerol is reacted with the acids.

상·하류 제품 정보

상류 원료

질산황산글리세린에틸알코올

하류 제품

1,2-디이트로글로세린2-모노니트로글리세린1,3-DINITROGLYCERIN

추가 설명

정의ChEBI: A nitroglycerol that is glycerol in which the hydrogen atoms of all three hydroxy groups are replaced by nitro groups. It acts as a prodrug, releasing nitric oxide to open blood vessels and so alleviate heart pain.