데이터를 보충하는 중입니다. 잠시 후 페이지를 새로 고치면 최신 내용을 볼 수 있습니다
기본 정보
- CAS
1204975-42-7- 표준 SMILES
Cc1c(Cc2ccccc2)nnc(N2CCN(c3cnc(C(C)(C)O)cn3)[C@H](C)C2)c1C- InChIKey
POERAARDVFVDLO-QGZVFWFLSA-N- 분자식
- C25H32N6O
- 평균 분자량
- 432.56 g/mol
이름 및 식별자
- 우선 이름
- 2-[4-(6-Benzyl-4,5-dimethylpyridazin-3-yl)-2-methyl-3,4,5,6-tetrahydro-2H-[1,2]bipyrazinyl-5-yl]-propan-2-ol
- 영어명
- 2-[4-(6-Benzyl-4,5-dimethylpyridazin-3-yl)-2-methyl-3,4,5,6-tetrahydro-2H-[1,2]bipyrazinyl-5-yl]-propan-2-ol
- 분자식
- C25H32N6O
- 분자량
- 432.56
이름 및 동의어
LEQ-506NVP-LEQ506LEQ506, 10 mM in DMSOLEQ-506,Inhibitor,LEQ 506,Smo,LEQ506,Smoothened,inhibit(R)-2-(5-(4-(6-Benzyl-4,5-dimethylpyridazin-3-yl)-2-methylpiperazin-1-yl)pyrazin-2-yl)propan-2-ol2-[4-(6-Benzyl-4,5-dimethylpyridazin-3-yl)-2-methyl-3,4,5,6-tetrahydro-2H-[1,2]bipyrazinyl-5-yl]-propan-2-ol2-Pyrazinemethanol, 5-[(2R)-4-[4,5-dimethyl-6-(phenylmethyl)-3-pyridazinyl]-2-methyl-1-piperazinyl]-α,α-dimethyl-2-[(R)-4-(6-benzyl-4,5-dimethyl-pyridazin-3-yl)-2-methyl-3,4,5,6-tetrahydro-2H-[1,2']bipyrazinyl-5'-yl]-propan-2-ol
데이터베이스 식별자
- CAS
1204975-42-7- PubChem CID
- 45100669
- ChEMBL
CHEMBL3133037- UNII
- 6SJX1T5HJD
물성
물리화학적 성질
- 녹는점
- 132 °C · 132 °C
- 끓는 점
- 685.4 · 685.4±55.0 °C(Predicted)
- 밀도
- 1.17 · 1.170±0.06 g/cm3(Predicted)
- 저장 조건
- -20 °C · Store at -20°C
- 용해도
- 100 mg/mL · DMSO : ≥ 100 mg/mL (231.18 mM)
- 산도 계수 (pKa)
- 12.84 · 12.84±0.29(Predicted)
- 물리적 상태
- Solid
- 색상
- White to yellow
화학 및 산업
응용 분야
용도LEQ506, is a second-generation inhibitor of smoothened (Smo) with IC50s of 2 and 4 nM in human and mouse, respectively.
공급사17 곳
Aladdin Scientific[email protected]
銳迪國際科技有限公司18024082417 · [email protected]
BOC Sciences1-631-485-4226; 16314854226 · [email protected]
上海陶术生物科技股份有限公司+1-781-999-5354; +1-00000000000 · [email protected]
上海德轩医药科技有限公司[email protected] · [email protected]
南通全益生物科技有限公司0513-66337626 18051384581 · [email protected]
上海一飞生物科技有限公司021-65675885 18964387627 · [email protected]
上海源叶生物科技有限公司18916372613 · [email protected]
南京凯姆铂医药科技有限公司025-66162170
安徽今昱生物化工产品技术研发有限公司055167162561 13295518198 · [email protected]
TargetMol中国（陶术生物）4008200310 15002144251 · [email protected]
ChemeGen 中国18818260767 · [email protected]
上海陶术生物科技股份有限公司
관련 반응
0건
현재 필터 조건에 해당하는 반응 기록이 없습니다.
화합물 노트
불러오는 중…