기본 정보
- CAS
40372-00-7- 표준 SMILES
Cl.N=C(N)c1ncn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)n1- InChIKey
PIGYMBULXKLTCJ-UHSSARMYSA-N- 분자식
- C8H14ClN5O4
- 평균 분자량
- 279.68 g/mol
개요
Taribavirin Hydrochloride is a hydrochloride salt form of taribavirin, an orally available prodrug of ribavirin, a synthetic nucleoside analog of ribofuranose with activity against a wide range of viruses, especially the hepatitis C virus and influenza virus. Taribavirin is converted into ribavirin, which is incorporated into viral nucleic acid, thereby inhibiting viral RNA synthesis, inducing viral genome mutations, and inhibiting normal viral replication.
이름 및 식별자
- 우선 이름
- Taribavirin Hydrochloride
- IUPAC
- 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,4-triazole-3-carboximidamide;hydrochloride
- 현지명
- 리바비린아미딘
- 영어명
- ribavirin amidine
- 분자식
- C8H13N5O4.ClH
- 분자량
- 279.68
이름 및 동의어
Taribavirin hydrochloride40372-00-7Viramidine hydrochlorideTaribavirin HClRibamidine hydrochlorideTCNRAVS 206D22JZE246PICN 31421-beta-D-Ribofuranosyl-1,2,4-triazole-3-carboxamidine hydrochloride1H-1,2,4-Triazole-3-carboximidamide, 1-beta-D-ribofuranosyl-, monohydrochlorideRefChem:187457
이름 더 보기
리바비린아미딘ribavirin amidine
Taribavirin (hydrochloride)Taribavirin hydrochloride [USAN]1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1H-1,2,4-triazole-3-carboximidamide hydrochlorideTaribavirin hydrochloride (USAN)1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,4-triazole-3-carboximidamide;hydrochlorideUNII-D22JZE246PViramidine (TN)C8H14ClN5O4
데이터베이스 식별자
- CAS
40372-00-7- PubChem CID
- 451447
- ChEMBL
CHEMBL2107375- UNII
- D22JZE246P
물성
구조 계산 물성
- 극성 표면적
- 151 Ų
- 수소 결합 공여자 수
- 6
- 수소 결합 수용자 수
- 7
- 회전 가능 결합 수
- 3
- 무거운 원자 수
- 18
- 형식 전하
- 0
- 복잡도
- 304
물리화학적 성질
- 녹는점
- 167 · 167-172°C
- 저장 조건
- -20 °C · -20°C Freezer
- 용해도
- DMSO(약간 용해됨, 가열), 메탄올(약간 용해됨)
- 물리적 상태
- 고체
- 색상
- 하얀색
화학적 성질
White Solid
화학 및 산업
약리 정보
MeSH Pharmacological Classification
Agents used in the prophylaxis or therapy of VIRUS DISEASES. Some of the ways they may act include preventing viral replication by inhibiting viral DNA polymerase; binding to specific cell-surface receptors and inhibiting viral penetration or uncoating; inhibiting viral protein synthesis; or blocking late stages of virus assembly.
응용 분야
용도Liver-targeting antiviral nucleoside analog; 3-carboxamidine prodrug of Ribavirin.
공급사23 곳
United Life Science020-82099279 18988968278 · [email protected]
銳迪國際科技有限公司18024082417 · [email protected]
上海梅凯科技有限公司021-68689288 15300790979 · [email protected]
天津普西唐生物医药科技有限公司010-60605840 · [email protected]
凯试（上海）科技有限公司021-50135380 · [email protected]
Alfa Chemistry1-516-6625404 · [email protected]
杭州六可生物科技有限公司+86-571-86912261 19975279805 · [email protected]
BOC Sciences16314854226 · [email protected]
上海陶术生物科技股份有限公司+1-781-999-5354; +1-00000000000 · [email protected]
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