Levovirin

HCID 460516CAS 206269-27-4

기본 정보

표준 SMILES: NC(=O)c1ncn([C@H]2O[C@@H](CO)[C@H](O)[C@@H]2O)n1
InChIKey: IWUCXVSUMQZMFG-RGDLXGNYSA-N
분자식: C8H12N4O5
평균 분자량: 244.2 g/mol
단동위원소 질량: 244.08076948

이름 및 식별자

우선 이름: Levovirin
IUPAC: 1-[(2S,3S,4R,5S)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,4-triazole-3-carboxamide
영어명: 1-[(2S,3S,4S,5S)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,4-triazole-3-carboxamide
분자식: C8H12N4O5
분자량: 244.2

이름 및 동의어

Levovirin206269-27-4L-RibavirinICN17261ICN 17261UNII-ZGF0S6S33QZGF0S6S33QICN-17261LEVOVIRIN [WHO-DD]DTXSID901746481H-1,2,4-Triazole-3-carboxamide, 1-beta-L-ribofuranosyl-1H-1,2,4-TRIAZOLE-3-CARBOXAMIDE, 1-BETA;-L-RIBOFURANOSYL-

이름 더 보기

L-Ribovirin1-β-L-ribofuranosyl-1,2,4-triazole-3-carboxamide1H-1,2,4-Triazole-3-carboxamide, 1-β-L-ribofuranosyl-1-[(2S,3S,4R,5S)-3,4-dihydroxy-5-methylol-tetrahydrofuran-2-yl]-1,2,4-triazole-3-carboxamide

1-[(2S,3S,4R,5S)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-1,2,4-triazole-3-carboxamide1-((2S,3S,4R,5S)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl)-1H-1,2,4-triazole-3-carboxamideRefChem:153236DTXCID30971391-((2S,3S,4R,5S)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1H-1,2,4-triazole-3-carboxamide1-[(2S,3S,4R,5S)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,4-triazole-3-carboxamide1-beta-l-ribofuranosyl-1h-1,2,4-triazole-3-carboxamide1-[(2S,3S,4S,5S)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,4-triazole-3-carboxamide

데이터베이스 식별자

CAS: 206269-27-4
PubChem CID: 460516
DTXSID: DTXSID90174648
ChEMBL: CHEMBL274536
UNII: ZGF0S6S33Q
Nikkaji: J1.303.803A

물성

구조 계산 물성

XLogP: -1.8
극성 표면적: 144 Å²
수소 결합 공여자 수: 4
수소 결합 수용자 수: 7
회전 가능 결합 수: 3
무거운 원자 수: 17
형식 전하: 0
복잡도: 304

실험 및 물리화학적 성질

DrugsPharmaceuticals -> Listed in ZINC15

물리화학적 성질

용해도: DMSO(약간 용해됨), 메탄올(약간 용해됨, 가열, 초음파 처리), 물(약간 용해됨)
물리적 상태: 고체
색상: 흰색에서 황백색까지
안정성: 흡습성

화학 및 산업

응용 분야

용도Levovirin is a monocyclic L-nucleosides with type 1 cytokine-inducing activity. Levovirin is the L-enantiomer of Ribavirin (R414475) with similar immunomodulatory activity but does not have direct antiviral activity or hemolytic anemia.