리마프로스트
(1S,3R,5R,6S,8R,10R,11S,13R,15R,16S,18R,20R,21S,23R,25R,26S,28R,30R,31R,32R,33R,34R,35R,36R,37R,38R,39R,40R,41R,42R)-5,10,15,20,25,30-hexakis(hydroxymethyl)-2,4,7,9,12,14,17,19,22,24,27,29-dodecaoxaheptacyclo[26.2.2.23,6.28,11.213,16.218,21.223,26]dotetracontane-31,32,33,34,35,36,37,38,39,40,41,42-dodecol;(E)-7-[(1R,2R,3R)-3-hydroxy-2-[(E,3S,5S)-3-hydroxy-5-methylnon-1-enyl]-5-oxocyclopentyl]hept-2-enoic acid
기본 정보
- CAS
88852-12-4- 표준 SMILES
CCCC[C@H](C)C[C@H](O)/C=C/[C@H]1[C@H](O)CC(=O)[C@@H]1CCCC/C=C/C(=O)O.OC[C@H]1O[C@@H]2O[C@H]3[C@H](O)[C@@H](O)[C@@H](O[C@H]4[C@H](O)[C@@H](O)[C@@H](O[C@H]5[C@H](O)[C@@H](O)[C@@H](O[C@H]6[C@H](O)[C@@H](O)[C@@H](O[C@H]7[C@H](O)[C@@H](O)[C@@H](O[C@H]1[C@H](O)[C@H]2O)O[C@@H]7CO)O[C@@H]6CO)O[C@@H]5CO)O[C@@H]4CO)O[C@@H]3CO- InChIKey
YBJQXILILWHFAT-UYXACNQFSA-N- 분자식
- C58H96O35
- 평균 분자량
- 1,353.4 g/mol
- 단동위원소 질량
- 1,352.5732147
개요
See other relationships...
이름 및 식별자
- 우선 이름
- (1S,3R,5R,6S,8R,10R,11S,13R,15R,16S,18R,20R,21S,23R,25R,26S,28R,30R,31R,32R,33R,34R,35R,36R,37R,38R,39R,40R,41R,42R)-5,10,15,20,25,30-hexakis(hydroxymethyl)-2,4,7,9,12,14,17,19,22,24,27,29-dodecaoxaheptacyclo[26.2.2.23,6.28,11.213,16.218,21.223,26]dotetracontane-31,32,33,34,35,36,37,38,39,40,41,42-dodecol;(E)-7-[(1R,2R,3R)-3-hydroxy-2-[(E,3S,5S)-3-hydroxy-5-methylnon-1-enyl]-5-oxocyclopentyl]hept-2-enoic acid
- IUPAC
- (1S,3R,5R,6S,8R,10R,11S,13R,15R,16S,18R,20R,21S,23R,25R,26S,28R,30R,31R,32R,33R,34R,35R,36R,37R,38R,39R,40R,41R,42R)-5,10,15,20,25,30-hexakis(hydroxymethyl)-2,4,7,9,12,14,17,19,22,24,27,29-dodecaoxaheptacyclo[26.2.2.23,6.28,11.213,16.218,21.223,26]dotetracontane-31,32,33,34,35,36,37,38,39,40,41,42-dodecol;(E)-7-[(1R,2R,3R)-3-hydroxy-2-[(E,3S,5S)-3-hydroxy-5-methylnon-1-enyl]-5-oxocyclopentyl]hept-2-enoic acid
- 현지명
- 리마프로스트
- 영어명
- Limaprost
- 분자식
- C36H60O30.C22H36O5
- 분자량
- 1353.36
이름 및 동의어
limaprost alfadex88852-12-4SCHEMBL619870orb1702005AKOS040747093T25728|A-Cyclodextrin, compd. with (2E)-7-[(1R,2R,3R)-3-hydroxy-2-[(1E,3S,5S)-3-hydroxy-5-methyl-1-nonen-1-yl]-5-oxocyclopentyl]-2-heptenoic acid(1:x)리마프로스트OpalmonOptiranProrenalZeflopto
이름 더 보기
OpaprosmonOP 1206-a-cyclodextrinOP 1306 - alpha-cyclodextrinLimaprost a-cyclodextrin clathrate17S,20-Dimethyl-trans-D2-PGE1 compd. with a-cyclodextrin
물성
구조 계산 물성
- 극성 표면적
- 570 Ų
- 수소 결합 공여자 수
- 21
- 수소 결합 수용자 수
- 35
- 회전 가능 결합 수
- 19
- 무거운 원자 수
- 93
- 형식 전하
- 0
- 복잡도
- 1,760
물리화학적 성질
- 녹는점
- 97 · 97-100 °C
화학 및 산업
응용 분야
개요Limaprost is an orally-active antithrombotic and vasodilator structurally related to alprostadil. Oral administration of limaprost causes a dose-dependent inhibition of platelet aggregation, an increase in platelet CAMP and a mild suppression of platelet adhesiveness. In patients with pulmonary emphysema, tuberculosis, and chronic lung disease, treatment with limaprost reportedly produces significant cardiac improvements.
용도Limaprost Alfadex is used in the sysnthesis of prostaglandins and its derivatives.
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