기본 정보
- CAS
1228559-81-6- 표준 SMILES
Cc1cccc(C)c1CNc1cc(C(=O)NCCOC(=O)CCCC(=O)O)cn2c(C)c(C)nc12- InChIKey
GPHPBXRKAJSSIC-UHFFFAOYSA-N- 분자식
- C26H32N4O5
- 평균 분자량
- 480.6 g/mol
- 단동위원소 질량
- 480.23727013
개요
Linaprazan glurate is a small molecule drug. The usage of the INN stem '-prazan' in the name indicates that Linaprazan glurate is a proton pump inhibitor, not dependent on acid activation. Linaprazan glurate is under investigation in clinical trial NCT07037875 (A Study Comparing the Effect and Safety of Linaprazan Glurate to Lansoprazole in Participants With Erosive Esophagitis (EE) Due to Gastroesophageal Reflux Disease (GERD)). Linaprazan glurate has a monoisotopic molecular weight of 480.24 Da.
이름 및 식별자
- 우선 이름
- Linaprazan Glurate
- IUPAC
- 5-[2-[[8-[(2,6-dimethylphenyl)methylamino]-2,3-dimethylimidazo[1,2-a]pyridine-6-carbonyl]amino]ethoxy]-5-oxopentanoic acid
- 영어명
- Pentanedioic acid, 1-[2-[[[8-[[(2,6-dimethylphenyl)methyl]amino]-2,3-dimethylimidazo[1,2-a]pyridin-6-yl]carbonyl]amino]ethyl] ester
- 분자식
- C26H32N4O5
- 분자량
- 480.56
이름 및 동의어
Linaprazan glurate1228559-81-6Linaprazan glurate [INN]3VG4D399DT1-(2-(((8-(((2,6-Dimethylphenyl)methyl)amino)-2,3-dimethylimidazo(1,2-a)pyridin-6-yl)carbonyl)amino)ethyl) pentanedioatePentanedioic acid, 1-(2-(((8-(((2,6-dimethylphenyl)methyl)amino)-2,3-dimethylimidazo(1,2-a)pyridin-6-yl)carbonyl)amino)ethyl) ester1-[2-[[[8-[[(2,6-Dimethylphenyl)methyl]amino]-2,3-dimethylimidazo[1,2-a]pyridin-6-yl]carbonyl]amino]ethyl] pentanedioatePentanedioic acid, 1-[2-[[[8-[[(2,6-dimethylphenyl)methyl]amino]-2,3-dimethylimidazo[1,2-a]pyridin-6-yl]carbonyl]amino]ethyl] esterRefChem:153490UNII-3VG4D399DT5-(2-(8-((2,6-Dimethylbenzyl)amino)-2,3-dimethylimidazo[1,2-a]pyridine-6-carboxamido)ethoxy)-5-oxopentanoic acid5-[2-[[8-[(2,6-dimethylphenyl)methylamino]-2,3-dimethylimidazo[1,2-a]pyridine-6-carbonyl]amino]ethoxy]-5-oxopentanoic acid
이름 더 보기
fast onset,Linaprazan glurate,gastric acid,gastrointestinal inflammatory diseases,peptic ulcer diseases,Inhibitor,inhibit5-[2-[[[8-[(2,6-dimethylphenyl)methylamino]-2,3-dimethyl-6-imidazo[1,2-a]pyridinyl]-oxomethyl]amino]ethoxy]-5-oxopentanoic acid
물성
구조 계산 물성
- XLogP
- 3.7
- 극성 표면적
- 122 Ų
- 수소 결합 공여자 수
- 3
- 수소 결합 수용자 수
- 7
- 회전 가능 결합 수
- 12
- 무거운 원자 수
- 35
- 형식 전하
- 0
- 복잡도
- 725
물리화학적 성질
- 밀도
- 1.25 · 1.25±0.1 g/cm3(Predicted)
- 저장 조건
- -20 °C · Store at -20°C
- 산도 계수 (pKa)
- 4.6 · 4.60±0.10(Predicted)
- 물리적 상태
- Solid
- 색상
- White to off-white
화학 및 산업
공급사15 곳
上海毕得医药科技股份有限公司400-1647117 13681763483 · [email protected]
上海凌飞医药科技有限公司13764318709 · [email protected]
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD+8613676922317 · [email protected]
HANGZHOU LEAP CHEM CO., LTD.+86-571-87711850 +86-15355479329 · [email protected]
滁州市科迈尔化工科技有限公司0550-5196001 15000891977 · [email protected]
药璞(上海)医药科技有限公司50929289 18616309303 · [email protected]
上海臻励生物科技有限公司021-16621358918; 18516310516;16621358918;13045646768 · [email protected]
ATK CHEMICAL COMPANY LIMITED+undefined-21-51877795 · [email protected]
深圳市创鑫生物科技有限公司13417589054 · [email protected]
TargetMol中国（陶术生物）4008200310 15002144251 · [email protected]
上海瀚鸿科技股份有限公司021-54306202 18917919676 · [email protected]
上海一飞生物科技有限公司021-65675885 18964387627 · [email protected]
上海传芊化工科技中心15869524721 · [email protected]
上海陶术生物科技股份有限公司
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