Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
산화오파민
산화오파민 · 6-Hydroxydopamine · D016627 · Topamine · oxidopamine · Oxidopamine hydrobromide · Hydrobromide, oxidopamine · Hydrochloride, oxidopamine
식별자 및 물리적 특성
| CAS No. | 1199-18-4 |
|---|---|
| 분자식 | C8H11NO3 |
| 평균 분자량 | 169.18 g/mol |
| 단동위원소 질량 | 169.07389321 g/mol |
| SMILES | NCCc1cc(O)c(O)cc1O |
| InChIKey | DIVDFFZHCJEHGG-UHFFFAOYSA-N |
| PubChem CID | 4624 |
| ChEMBL | CHEMBL337702 |
| ChEBI | CHEBI:78741 |
| EC No. | 214-842-3 |
| DTXSID | DTXSID0036768 |
| 현지명 | 산화오파민 |
화학 및 물리적 성질
| XLogP | 0.2 |
|---|---|
| 극성 표면적 | 86.7 |
| 수소 결합 공여자 수 | 4 |
| 수소 결합 수용자 수 | 4 |
| 회전 가능 결합 수 | 2 |
| 무거운 원자 수 | 12 |
| 형식 전하 | 0 |
| 복잡도 | 142 |
| 녹는점 | 232 °C |
| Physical Description | 6-hydroxydopamine is a solid. Used as a pharmacological agent. |
| Collision Cross Section | 143 Ų [M+H]+ [CCS Type: DTMethod: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]143.2 Ų [M+H]+ |
| 끓는 점 | 298.46°C (rough estimate) |
| 밀도 | 1.2435 (rough estimate) |
| 굴절률 | 1.5100 (estimate) |
| EPA | 6-Hydroxydopamine (1199-18-4) |
안전 및 규제
| 운송 라벨(DOT) | Poison |
|---|---|
| 화재 위험 | Flash point data for this chemical are not available. It is probably combustible. (NTP, 1992) |
| 건강 유해성 | SYMPTOMS: Symptoms of exposure to this chemical may include a prolonged decomposition in catecholamine content of the heart (shown to be due to the destruction of sympathetic nerve endings). (NTP, 1992) |
| 반응성 그룹 | Amines, Phosphines, and Pyridines |
| Reactivity Profile | Amines are chemical bases. They neutralize acids to form salts plus water. These acid-base reactions are exothermic. The amount of heat that is evolved per mole of amine in a neutralization is largely independent of the strength of the amine as a base. Amines may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides. |
| Air and Water Reactions | No rapid reaction with air. No rapid reaction with water. |
| 소화 | Fires involving this material can be controlled with a dry chemical, carbon dioxide or Halon extinguisher. (NTP, 1992) |
| 응급 처치 | EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop. |
| 비화재 누출 대응 | STORAGE PRECAUTIONS: You should store this material in a refrigerator. (NTP, 1992) |
| Isolation and Evacuation | Excerpt from ERG Guide 154 [Substances - Toxic and/or Corrosive (Non-Combustible)]: |
| Personal Protective Equipment (PPE) | RECOMMENDED RESPIRATOR: Where the neat test chemical is weighed and diluted, wear a NIOSH-approved half face respirator equipped with a combination filter cartridge, i.e. organic vapor/acid gas/HEPA (specific for organic vapors, HCl, acid gas, SO2 and a high efficiency particulate filter). (NTP, 1992) |
용도
용도
Adrenergic (ophthalmic).
일반 설명
Solid. Used as a pharmacological agent.