Oxiracetam

HCID 4626
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기본 정보

CAS
62613-82-5
표준 SMILES
NC(=O)CN1CC(O)CC1=O
InChIKey
IHLAQQPQKRMGSS-UHFFFAOYSA-N
분자식
C6H10N2O3
평균 분자량
158.16 g/mol
단동위원소 질량
158.06914218

개요

Oxiracetam is an organonitrogen compound and an organooxygen compound. It is functionally related to an alpha-amino acid.

이름 및 식별자

우선 이름
Oxiracetam
IUPAC
2-(4-hydroxy-2-oxopyrrolidin-1-yl)acetamide
영어명
Oxiracetam
분자식
C6H10N2O3
분자량
158.16

이름 및 동의어

oxiracetam62613-82-5ISF-2522CGP 21690EOxiracetamumCGP-21690EGNF-PF-1005P7U817352GRefChem:168933N06BX072-(4-hydroxy-2-oxopyrrolidin-1-yl)acetamide4-Hydroxy-2-oxopyrrolidine-N-acetamide
이름 더 보기
4-hydroxy-2-oxo-1-pyrrolidineacetamidisf2522NeuromeOlaxitamOlacetamNeuractivCGP 21690oxiraceta
Hydroxypiracetam4-Hydroxy-2-oxo-1-pyrrolidineacetamideOxiracetam(Random Configuration)1-Pyrrolidineacetamide, 4-hydroxy-2-oxo-ISF 2522CT-848MFCD00242951Oriest

데이터베이스 식별자

CAS
62613-82-5
PubChem CID
4626
DTXSID
DTXSID9045180
ChEMBL
CHEMBL36633
ChEBI
CHEBI:134788
UNII
P7U817352G
EC Number
636-370-0
Nikkaji
J19.582K

물성

구조 계산 물성

XLogP
-2.2
극성 표면적
83.6 Ų
수소 결합 공여자 수
2
수소 결합 수용자 수
3
회전 가능 결합 수
2
무거운 원자 수
11

실험 및 물리화학적 성질

DrugsDEA NFLIS-Drug Category -> Stimulants

물리화학적 성질

녹는점
165 · 165-168 °C
끓는 점
494.6 · 494.6±40.0 °C(Predicted)
밀도
1.416 · 1.416
저장 조건
Sealed in dry,Room Temperature
용해도
DMSO (Slightly, Heated), Methanol (Slightly, Heated)
물리적 상태
고체

화학적 성질

Whie Solid

안전 및 규제

GHS 분류

GHS Classification · 4건

Warning

H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]

P264, P264+P265, P280, P302+P352, P305+P351+P338, P321, P332+P317, P337+P317, and P362+P364 (click each P-code to see the statement)

Aggregated GHS information provided per 39 reports by companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

유해성 정보

Hazard Classes and CategoriesSkin Irrit. 2 (100%)

안전 데이터

wgk
3
rtecs
UX9656638
HS 번호
2933.79.8500
risk_code
36/38
hazard_code
Xi
safety_code
26-36

화학 및 산업

약리 정보

ATC Code · 2건

N - Nervous system

QN - Nervous system

MeSH Pharmacological Classification · 2건

A loosely defined grouping of drugs that have effects on psychological function. Here the psychotropic agents include the antidepressive agents, hallucinogens, and tranquilizing agents (including the antipsychotics and anti-anxiety agents).

Drugs used to specifically facilitate learning or memory, particularly to prevent the cognitive deficits associated with dementias. These drugs act by a variety of mechanisms.

응용 분야 · 2건

개요Oxiracetam is a structural analogue of piracetam. This compound has enhancing effects on vigilance and memory. In comparison with piracetam, oxiracetam exhibits greater improvement in memory (Itil et al., 1986) and has been used extensively for the treatment of dementia, including AD, VaD, MID (Baumel et al., 1989; Dysken et al., 1989), and mixed forms. Green et al. (1992) failed to demonstrate a difference from placebo in AD patients. In contrast, Maina et al. (1989) studied 289 patients with MID in a double-blind placebo-controlled trial and after 12 weeks of treatment found that oxiracetam reduced behavioural symptoms.

용도Oxiracetam is a 4-hydroxy analog of piracetam with psychostimulant activity, reportedly useful in relieving the symptoms of cerebral insufficiency in the elderly.

상·하류 제품 정보

공급사100 곳

北京华美互利生物化工010-56205725 · [email protected]
梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
河南金巴克新材料科技有限公司18737135779 · [email protected]
LGM Pharma1-(800)-881-8210 · [email protected]

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