페놀레드

Phenol Red

HCID 4766CAS 143-74-8
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기본 정보

표준 SMILES
O=S1(=O)OC(c2ccc(O)cc2)(c2ccc(O)cc2)c2ccccc21
InChIKey
BELBBZDIHDAJOR-UHFFFAOYSA-N
분자식
C19H14O5S
평균 분자량
354.4 g/mol
단동위원소 질량
354.05619455

개요

Phenol red is 3H-2,1-Benzoxathiole 1,1-dioxide in which both of the hydrogens at position 3 have been substituted by 4-hydroxyphenyl groups. A pH indicator changing colour from yellow below pH 6.8 to bright pink above pH 8.2, it is commonly used as an indicator in cell cultures and in home swimming pool test kits. It is also used in the (now infrequently performed) phenolsulfonphthalein (PSP) test for estimation of overall blood flow through the kidney. It has a role as a diagnostic agent, an acid-base indicator and a two-colour indicator. It is a member of phenols, a 2,1-benzoxathiole, a sultone and an arenesulfonate ester.

이름 및 식별자

우선 이름
Phenol Red
IUPAC
4-[3-(4-hydroxyphenyl)-1,1-dioxo-2,1λ6-benzoxathiol-3-yl]phenol
현지명
페놀레드
영어명
Phenol Red
분자식
C19H14O5S
분자량
354.38

이름 및 동의어

PHENOL REDphenolsulfonphthalein143-74-8FenolipunaSulphonthalPSP (indicator)PhenolsulphonphthaleinDTXSID8022408NSC-10459I6G9Y0J1OJDTXCID202408CHEBI:31991
이름 더 보기
술폰탈페놀리푸나4,4$$@@-(3H-2,1-벤족사티올-3-일리덴)디-페놀S,S-디산화물술펜탈페놀레드페놀레드용액페놀술포네프탈레인페놀술폰프탈레인페놀레드페놀설폰프탈레인PRA-HYDROXY-A A-BIS(P-HYDROXYPHENYL)-O-TOLUENESULFONIC ACID G-SULTONEPRGRNR3C3P3532-5GPhenolrdePhenol re
Phenol, 4,4'-(3H-2,1-benzoxathiol-3-ylidene)bis-, (S,S-dioxide)3,3-bis(4-hydroxyphenyl)-3H-2,1??-benzoxathiole-1,1-dioneRefChem:1728812-(Bis(4-hydroxyphenyl)methyliumyl)benzenesulfonate205-609-7SulfonphthalSulphentalPhenolred

데이터베이스 식별자

CAS
143-74-8
PubChem CID
4766
DTXSID
DTXSID8022408
ChEMBL
CHEMBL258921
ChEBI
CHEBI:31991
UNII
I6G9Y0J1OJ
EC Number
205-609-7
Nikkaji
J3.779.134B

물성

구조 계산 물성

XLogP
3
극성 표면적
92.2 Ų
수소 결합 공여자 수
2
수소 결합 수용자 수
5
회전 가능 결합 수
2
무거운 원자 수
25

실험 및 물리화학적 성질

Chemical ClassesDyes -> Indicator Dyes
LogP3.02
Animal DrugsPharmaceuticals -> UK Veterinary Medicines Directorate List
Endocrine DisruptorsPotential endocrine disrupting compound
Physical DescriptionOdorless, red solid; Available as pure compound, soluble monosodium salt, and dilute solutions; [CHEMINFO]
Collision Cross Section179.8 Ų [M+H]+ [CCS Type: DT; Buffer gas: N2; Ionization: ESI+; Dataset: TOXCAST; Source Identifier: DTXSID2044420]

물리화학적 성질

녹는점
300 °C · >300 °C
끓는 점
300 °C · >300°C
밀도
1.445 Mg · 1.445 Mg m-3
굴절률
1.53 · 1.5300 (estimate)
인화점
300 °C · >300°C
저장 조건
no restrictions.

화학적 성질

dark red powder

안전 및 규제

GHS 분류

GHS Classification · 5건

This chemical does not meet GHS hazard criteria for 1.4% (3 of 211) of reports.

Warning

H315 (98.6%): Causes skin irritation [Warning Skin corrosion/irritation]

P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 211 reports by companies from 15 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

유해성 정보

Regulatory Information · 2건

Chemical: Phenol, 4,4'-(3H-2,1-benzoxathiol-3-ylidene)bis-, S,S-dioxide

Phenolsulfonphthalein: Does not have an individual approval but may be used under an appropriate group standard

Hazards SummaryDust may be irritating if inhaled; [CHEMINFO]
Hazard Classes and CategoriesSkin Irrit. 2 (98.6%)

안전 데이터

wgk
3
tsca
TSCA listed
rtecs
SJ7490000
독성
LD50 orl-rat: >600 mg/kg CTOXAO 4(2),185,71
HS 번호
29349990
risk_code
36/37/38-34

화학 및 산업

약리 정보

ATC Code · 2건

V - Various

QV - Various

MeSH Pharmacological Classification · 2건

Substances used for the detection, identification, analysis, etc. of chemical, biological, or pathologic processes or conditions. Indicators are substances that change in physical appearance, e.g., color, at or approaching the endpoint of a chemical titration, e.g., on the passage between acidity and alkalinity. Reagents are substances used for the detection or determination of another substance by chemical or microscopical means, especially analysis. Types of reagents are precipitants, solvents, oxidizers, reducers, fluxes, and colorimetric reagents. (From Grant & Hackh's Chemical Dictionary, 5th ed, p301, p499)

Chemicals and substances that impart color including soluble dyes and insoluble pigments. They are used in INKS; PAINTS; and as INDICATORS AND REAGENTS.

용도 및 제조

UsesUsed as a pH indicator and marker of kidney function and other physiological functions; [CHEMINFO] Used as a pH indicator for the pH range of 6.4-8.2; [Ullmann]
Household ProductsInformation on 1 consumer products that contain Phenolsulfonphthalein in the following categories is provided:
General Manufacturing InformationPhenol, 4,4'-(1,1-dioxido-3H-2,1-benzoxathiol-3-ylidene)bis-: ACTIVE
응용 분야 · 2건

개요Phenol red belongs to the class of triphenylmethane dyes and is widely used in the textile industry.

용도Phenol red is used as a non absorbed marker in gravimetric method. It is a pH indicator used in cell biology laboratories and in home swimming pool test kits. It is used to check the kidney function based on the excreted phenol red by colorimetric method.

제조 방법

Phenol red is prepared in Dulbecco′s Phosphate Buffered Saline.

상·하류 제품 정보

공급사50 곳

国药集团化学试剂有限公司86-21-63210123 · [email protected]
北京华美互利生物化工010-56205725 · [email protected]
梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
河北创海生物科技有限公司+86-86-13131129325 · [email protected]
추가 설명 · 1건

정의ChEBI: 3H-2,1-Benzoxathiole 1,1-dioxide in which both of the hydrogens at position 3 have been substituted by 4-hydroxyphenyl groups. A pH indicator changing colour from yellow below pH 6.8 to bright pink above pH 8.2, it is commonly used as an indicator in cell cultures and in home swimming pool test kits. It is also used in the (now infrequently performed) phenolsulfonphthalein (PSP) test for estimation of overall blood flow through the kidney.

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