Zantac

HCID 47909CAS 66357-59-3

부분 구조 검색 유사 구조 찾기

기본 정보

표준 SMILES: CNC(=C[N+](=O)[O-])NCCSCc1ccc(CN(C)C)o1.Cl
InChIKey: GGWBHVILAJZWKJ-UHFFFAOYSA-N
분자식: C13H23ClN4O3S
평균 분자량: 350.87 g/mol
단동위원소 질량: 350.11793928

개요

See also: Ranitidine Hydrochloride (annotation moved to).

이름 및 식별자

우선 이름: Zantac
IUPAC: 1-N'-[2-[[5-[(dimethylamino)methyl]furan-2-yl]methylsulfanyl]ethyl]-1-N-methyl-2-nitroethene-1,1-diamine;hydrochloride

이름 및 동의어

ZANTACRefChem:934486SantanolTanidinaToriolRadin71130-06-8RaniberlranicDigestosanServiradineAlvidina

이름 더 보기

ArtomilAzuranitMideranNoktomeQuadrinRanibertaRanicuxRanidil

데이터베이스 식별자

CAS: 66357-59-3、71130-06-8
PubChem CID: 47909
DTXSID: DTXSID201015892
UNII: BK76465IHM
EC Number: 275-207-4

물성

구조 계산 물성

극성 표면적: 112 Å²
수소 결합 공여자 수: 3
수소 결합 수용자 수: 7
회전 가능 결합 수: 9
무거운 원자 수: 22
형식 전하: 0
복잡도: 347

안전 및 규제

GHS 분류

GHS Classification · 4건

Danger

H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]

P233, P260, P261, P264, P264+P265, P271, P272, P280, P284, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P333+P317, P337+P317, P342+P316, P362+P364, P403, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 54 reports by companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

유해성 정보

Hazard Classes and CategoriesSkin Irrit. 2 (100%)

화학 및 산업

약리 정보

MeSH Pharmacological Classification · 2건

Various agents with different action mechanisms used to treat or ameliorate PEPTIC ULCER or irritation of the gastrointestinal tract. This has included ANTIBIOTICS to treat HELICOBACTER INFECTIONS; HISTAMINE H2 ANTAGONISTS to reduce GASTRIC ACID secretion; and ANTACIDS for symptomatic relief.

Drugs that selectively bind to but do not activate histamine H2 receptors, thereby blocking the actions of histamine. Their clinically most important action is the inhibition of acid secretion in the treatment of gastrointestinal ulcers. Smooth muscle may also be affected. Some drugs in this class have strong effects in the central nervous system, but these actions are not well understood.