CAS 1271022-90-2 Bms-911543 (HCID 50922691)

부분 구조 검색 유사 구조 찾기

기본 정보

CAS: 1271022-90-2
표준 SMILES: CCn1c(C(=O)N(C2CC2)C2CC2)cc2c3c(ncn3C)c(Nc3cc(C)n(C)n3)nc21
InChIKey: JCINBYQJBYJGDM-UHFFFAOYSA-N
분자식: C23H28N8O
평균 분자량: 432.5 g/mol
단동위원소 질량: 432.23860752

개요

BMS-911543 has been used in trials studying the treatment of Cancer.

이름 및 식별자

우선 이름: Bms-911543
IUPAC: N,N-dicyclopropyl-7-[(1,5-dimethylpyrazol-3-yl)amino]-10-ethyl-3-methyl-3,5,8,10-tetrazatricyclo[7.3.0.02,6]dodeca-1,4,6,8,11-pentaene-11-carboxamide
영어명: BMS-911543
분자식: C23H28N8O
분자량: 432.52

이름 및 동의어

BMS-9115431271022-90-2BMS 911543JAK2 INHIBITOR BMS-9115437N03P021J8DTXSID00155403RefChem:120755DTXCID1077894N,N-dicyclopropyl-7-((1,5-dimethyl-1H-pyrazol-3-yl)amino)-10-ethyl-3-methyl-3,5,8,10-tetraazatricyclo(7.3.0.0^(2,6))dodeca-1,4,6,8,11-pentaene-11-carboxamideBMS911543MFCD22200575N,N-dicyclopropyl-4-((1,5-dimethyl-1H-pyrazol-3-yl)amino)-6-ethyl-1-methyl-1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridine-7-carboxamide

이름 더 보기

CS-785BMS-911543 ，S7144BMS-911543, 10 mM in DMSOJanus kinase,inhibit,BMS 911543,Inhibitor,JAK,BMS-911543N,N-Dicyclopropyl-4-((1,5-dimethyl-1H-pyrazol-3-yl)amino)-6-ethyl-1-methyl-1,6-dihydroimidazo[N,N-Dicyclopropyl-4-[(1,5-dimethyl-1H-pyrazol-3-yl)amino]-6-ethyl-1,6-dihydro-1-methyl-imidazo[4,5-d]pyrrolo[2,3-b]pyridine-7-carboxamide

Imidazo[4,5-d]pyrrolo[2,3-b]pyridine-7-carboxamide, N,N-dicyclopropyl-4-[(1,5-dimethyl-1H-pyrazol-3-yl)amino]-6-ethyl-1,6-dihydro-1-methyl-N,N-Dicyclopropyl-4-[(1,5-Dimethyl-1h-Pyrazol-3-Yl)amino]-6-Ethyl-1-Methyl-1,6-Dihydroimidazo[4,5-D]pyrrolo[2,3-B]pyridine-7-CarboxamideN,N-dicyclopropyl-4-(1,5-dimethyl-1H-pyrazol-3-ylamino)-6-ethyl-1-methyl-1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridine-7-carboxamideN,N-dicyclopropyl-7-[(1,5-dimethylpyrazol-3-yl)amino]-10-ethyl-3-methyl-3,5,8,10-tetrazatricyclo[7.3.0.02,6]dodeca-1,4,6,8,11-pentaene-11-carboxamideUNII-7N03P021J8JCINBYQJBYJGDM-UHFFFAOYSA-NIMIDAZO(4,5-D)PYRROLO(2,3-B)PYRIDINE-7-CARBOXAMIDE, N,N-DICYCLOPROPYL-4-((1,5-DIMETHYL-1H-PYRAZOL-3-YL)AMINO)-6-ETHYL-1,6-DIHYDRO-1-METHYL-THCYT3

물성

구조 계산 물성

XLogP: 2.9
극성 표면적: 85.8 Å²
수소 결합 공여자 수: 1
수소 결합 수용자 수: 5
회전 가능 결합 수: 6
무거운 원자 수: 32
형식 전하: 0
복잡도: 717

실험 및 물리화학적 성질

DrugsPharmaceuticals -> Listed in ZINC15

물리화학적 성질

저장 조건: 2 · under inert gas (nitrogen or Argon) at 2–8 °C
용해도: 43.3 mg/mL · ≥43.3 mg/mL in DMSO with gentle warming; insoluble in H2O; ≥9.8 mg/mL in EtOH with gentle warming and ultrasonic
물리적 상태: 가루
색상: White to light yellow

안전 및 규제

안전 데이터

신호 어: Warning
유해·위험 문구: 암호 유해·위험 문구 위험 등급 범주 신호 어 그림 문자 P- 코드 H315

화학 및 산업

응용 분야

용도BMS 911543 is a functionally selective small molecule inhibitor of JAK2 and have been developed as a treatment for leukemia.

공급사75 곳

南通飞宇生物科技有限公司0513-68819626 15152877458 · [email protected]

Career Henan Chemica Co+86-0371-86658258 +86-13203830695 · [email protected]

武汉英诺医药科技有限公司+86-027-59232304 15387063101 · [email protected]

成都彼样生物科技有限公司18108052721 · [email protected]

南京林叶化学试剂有限公司13376084917 13376082704 · [email protected]

화합물 노트

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Bms-911543