Lauramidopropyl Dimethylamine (HCID 51392)

개요

The CIR Expert Panel concluded that the 24 fatty acid amidopropyl dimethylamines ingredients listed below are safe in cosmetics when they are formulated to be non-sensitizing, which may be based on a QRA...Lauramidopropyl Dimethylamine...

이름 및 식별자

우선 이름: Lauramidopropyl Dimethylamine
IUPAC: N-[3-(dimethylamino)propyl]dodecanamide
현지명: 라우라미도프로필다이메틸아민
영어명: N-[3-(DIMETHYLAMINO)PROPYL]LAURAMIDE
분자식: C17H36N2O
분자량: 284.48

이름 및 동의어

N-[3-(dimethylamino)propyl]dodecanamideLauramidopropyl dimethylamineN-[3-(Dimethylamino)propyl]lauramideN-(3-(Dimethylamino)propyl)dodecanamideSCHERCODINE LDodecanamide, N-[3-(dimethylamino)propyl]-(LAURYLAMIDOPROPYL)DIMETHYLAMINEDTXSID8044913FS588RR72JDodecanamide, N-(3-(dimethylamino)propyl)-NSC-79892ZOHAR AMIDO AMINE L

이름 더 보기

라우라미도프로필다이메틸아민Lexamine L 13PKO12Einecs 221-661-3Dimethylaminopropyl lauramideLaurylamidopropylDimethylAmineN,N-DimethyllauramidopropylamineLauric 3-dimethylaminopropylamideDodecanoylamidopropyldimethylamineLauroyl(dimethyl amino propyl)amine

3-dodecanamidopropyldimethylamineDTXCID6024913DIMETHYLAMINOPROPYLLAURYLAMIDEN-(3-(Dimethylamino)propyl)lauramide1147459-12-8N,N-DIMETHYLAMINOPROPYLDODECYLAMIDEAmides, C12-18, N-(3-(dimethylamino)propyl)Amides, C12-18, N-[3-(dimethylamino)propyl]

데이터베이스 식별자

CAS: 1147459-12-8、3179-80-4
PubChem CID: 51392
DTXSID: DTXSID8044913
ChEMBL: CHEMBL3185963
UNII: FS588RR72J
EC Number: 221-661-3、689-272-5
Nikkaji: J27.687A

물성

구조 계산 물성

XLogP: 5.1
극성 표면적: 32.3 Å²
수소 결합 공여자 수: 1
수소 결합 수용자 수: 2
회전 가능 결합 수: 14
무거운 원자 수: 20
형식 전하: 0
복잡도: 217

실험 및 물리화학적 성질

Cosmetics · 3건

Cosmetic ingredients (Lauramidopropyl Dimethylamine) -> CIR (Cosmetic Ingredient Review)

Personal care product

Antistatic

Physical DescriptionLiquid; Other Solid; CBI

Collision Cross Section181.8 Å² [M+Na]+ [CCS Type: DT; Buffer gas: N2; Ionization: ESI+; Dataset: TOXCAST; Source Identifier: DTXSID8044913]

물리화학적 성질

녹는점: 34.5 · 34.5-38.5 °C(lit.)
끓는 점: 171 · 171-194 °C(Press: 2 Torr)
밀도: 0.882 · 0.882±0.06 g/cm3(Predicted)
인화점: 230 °F · >230 °F
용해도: 클로로포름(약간 용해됨), 메탄올(약간 용해됨)
산도 계수 (pKa): 16.29 · 16.29±0.46(Predicted)
물리적 상태: 저융점 고체
색상: 흰색에서 황백색까지
화장품 원료 기능: 대전방지제
InChI: InChI=1S/C17H36N2O/c1-4-5-6-7-8-9-10-11-12-14-17(20)18-15-13-16-19(2)3/h4-16H2,1-3H3,(H,18,20)
InChIKey: TWMFGCHRALXDAR-UHFFFAOYSA-N
SMILES: C(NCCCN(C)C)(=O)CCCCCCCCCCC
LogP: 4.561 · 4.561 (est)
표면장력: 27.8 mN/m · 27.8mN/m at 1g/L and 20℃
EPA: 3 · Dodecanamide, N-[3-(dimethylamino)propyl]- (3179-80-4)

안전 및 규제

GHS 분류

GHS Classification · 6건

This chemical does not meet GHS hazard criteria for 0.2% (1 of 653) of reports.

Danger

H302 (25.7%): Harmful if swallowed [Warning Acute toxicity, oral]

P260, P261, P264, P264+P265, P270, P272, P273, P280, P301+P317, P301+P330+P331, P302+P352, P302+P361+P354, P304+P340, P305+P354+P338, P316, P317, P321, P330, P332+P317, P333+P317, P362+P364, P363, P391, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 653 reports by companies from 13 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Danger

유해성 정보

Regulatory Information · 4건

Chemical: Dodecanamide, N-[3-(dimethylamino)propyl]-

Dodecanamide, N-[3-(dimethylamino)propyl]- is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Dodecanamide, N-[3-(dimethylamino)propyl]- are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

Status: Active Update: 23-02-2021 https://echa.europa.eu/registration-dossier/-/registered-dossier/10713

Dodecanamide, N-3-(dimethylamino)propyl-: Does not have an individual approval but may be used as a component in a product covered by a group standard. It is not approved for use as a chemical in its own right.

Other Safety InformationIMAP assessments - Fatty acid amido propyl dimethylamines: Human health tier II assessment

Hazard Classes and Categories · 3건

Acute Tox. 4 (25.7%)

Acute Tox. 4 (100%)

Skin corrosion - category 1

독성 정보

Toxicity Summary · 2건

The CIR Expert Panel concluded that the 24 fatty acid amidopropyl dimethylamines ingredients listed below are safe in cosmetics when they are formulated to be non-sensitizing, which may be based on a QRA...Lauramidopropyl Dimethylamine...

Safe for use in cosmetics, with qualifications

안전 데이터

wgk: 2
tsca: TSCA listed
risk_code: 36/37/38
hazard_code: Xi
safety_code: 26
Hazard Classifications: Eye Irrit. 2Skin Irrit. 2STOT SE 3
스토리지 클래스: 11 - Combustible Solids

화학 및 산업

용도 및 제조

UsesCIR ingredient: Lauramidopropyl Dimethylamine

U.S. Production2023: 10,000,000 - <25,000,000 lb

Industry UsesIntermediate

Use ClassificationCosmetics -> Antistatic

General Manufacturing Information · 2건

All Other Basic Organic Chemical Manufacturing

Dodecanamide, N-[3-(dimethylamino)propyl]-: ACTIVE

응용 분야

용도N-(3-(Dimethylamino)propyl)dodecanamide is used in the study of surface chemistry and colloids as a new surfactnt for hydrate anti-agglomeration in hydrocarbon flowlines and seabed oil capture.