Potassium Bicarbonate

HCID 516893CAS 17353-70-7

기본 정보

표준 SMILES
O=C([O-])O.[K+]
InChIKey
TYJJADVDDVDEDZ-UHFFFAOYSA-M
분자식
CHKO3
평균 분자량
100.115 g/mol
단동위원소 질량
99.95627537

이름 및 식별자

우선 이름
Potassium Bicarbonate
IUPAC
potassium hydrogen carbonate

이름 및 동의어

Potassium bicarbonate298-14-6Potassium hydrogen carbonatePotassium hydrogencarbonatePotassium acid carbonateMonopotassium carbonateCARBONIC ACID, MONOPOTASSIUM SALTArmicarbKHCO3KafyloxKaligreenMilstop
이름 더 보기
Purple kHM5Z15LEBNINS NO.501(II)INS-501(II)E-501(II)Potassium bicarbonate (USP)Potassium bicarbonate [USP]DTXSID0021177

데이터베이스 식별자

CAS
17353-70-7、298-14-6
PubChem CID
516893
DTXSID
DTXSID0021177
ChEMBL
CHEMBL2106975
ChEBI
CHEBI:81862
UNII
HM5Z15LEBN
EC Number
206-059-0
Nikkaji
J8.578B

물성

구조 계산 물성

극성 표면적
60.4 Ų
수소 결합 공여자 수
1
수소 결합 수용자 수
3
회전 가능 결합 수
0
무거운 원자 수
5

실험 및 물리화학적 성질

Density2.17 @25 °C
Solubility · 2건

Soluble

Freely soluble in water. Insoluble in ethanol

Melting PointDecomposes before melting
Physical Description · 3건

CBI; Dry Powder; Liquid

Colourless crystals or white powder or granules

Colorless or white solid; [Merck Index] White odorless granules; [Alfa Aesar MSDS]

Dissociation Constants6.37

안전 및 규제

GHS 분류

GHS Classification · 3건

This chemical does not meet GHS hazard criteria for 99.7% (300 of 301) of all reports.

Not Classified;Reported as not meeting GHS hazard criteria by 300 of 301 companies (only 0.3% companies provided GHS information). For more detailed information, please visit ECHA C&L website.

Aggregated GHS information provided per 301 reports by companies from 3 notifications to the ECHA C&L Inventory.;Reported as not meeting GHS hazard criteria per 300 of 301 reports by companies.;There is 1 notification provided by 1 of 301 reports by companies with hazard statement code(s).;Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

유해성 정보

Regulatory Information · 6건

Chemical: Carbonic acid, monopotassium salt

Commission Regulation No 844/2012

Carbonic acid, potassium salt (1:1) is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Carbonic acid, potassium salt (1:1) are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

2008/127, Reg. (EU) 2017/195, Reg. (EU) 2020/1160, Reg. (EU) 2021/1452, Reg. (EU) 2021/745, Reg. (EU) No 540/2011, Reg. (EU) No 735/2012

Status: Active Update: 28-06-2021 https://echa.europa.eu/registration-dossier/-/registered-dossier/13190

Potassium bicarbonate: Does not have an individual approval but may be used under an appropriate group standard

Other Safety InformationIMAP assessments - Carbonic acid, monopotassium salt: Human health tier I assessment
Hazards Summary · 1건

Not irritating to skin or eyes of rabbits; Effects to bladder seen in feeding studies of rats due to alkalizing properties (urine pH > 8) and not to toxic properties of the compound itself; [IUCLID] Causes adrenal cortex hyperplasia and changes in tubules in 13-week oral study of rats (218,400 mg/kg); [RTECS] May cause irritation; [Alfa Aesar MSDS]

EPA Safer ChemicalChemical: Potassium bicarbonate; Green circle - The chemical has been verified to be of low concern based on experimental and modeled data.
Hazard Classes and CategoriesNot Classified

안전 및 보호

Protective Action Criteria (PAC) · 3건

6.2 [mg/m3]

68 [mg/m3]

410 [mg/m3]

독성 정보

Toxicity Summary · 2건

The CIR Expert Panel concluded that the following 6 carbonate salts are safe in the present practices of use and concentration, as described in this safety assessment, when formulated to be non-irritating...Potassium Bicarbonate...

Safe for use in cosmetics, with qualifications

규제 정보

Regulatory Information · 6건

Chemical: Carbonic acid, monopotassium salt

Commission Regulation No 844/2012

Carbonic acid, potassium salt (1:1) is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Carbonic acid, potassium salt (1:1) are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

2008/127, Reg. (EU) 2017/195, Reg. (EU) 2020/1160, Reg. (EU) 2021/1452, Reg. (EU) 2021/745, Reg. (EU) No 540/2011, Reg. (EU) No 735/2012

Status: Active Update: 28-06-2021 https://echa.europa.eu/registration-dossier/-/registered-dossier/13190

Potassium bicarbonate: Does not have an individual approval but may be used under an appropriate group standard

화학 및 산업

약리 정보

ATC Code · 2건

A - Alimentary tract and metabolism;A12 - Mineral supplements;A12B - Potassium;A12BA - Potassium;A12BA04 - Potassium hydrogencarbonate

QA - Alimentary tract and metabolism;QA12 - Mineral supplements;QA12B - Potassium;QA12BA - Potassium;QA12BA04 - Potassium hydrogencarbonate

Pharmacodynamics · 1건

Potassium is the principal intracellular cation in most body tissues. The concentration of potassium ions is essential to conduct nerve impulses in specialized tissues like brain, heart and skeletal muscle, as well as to maintain normal renal function, acid-base balance, and cellular metabolic functions. The use of compounds containing bicarbonate is showed to produce the release of CO2. This effect has been one of the problems of the use of potassium bicarbonate as it can cause eructation.

Mechanism of Action · 1건

The antacid potential of potassium bicarbonate is attained by increasing the gastrointestinal pH by neutralizing hydrochloric acid. The increase in pH results in suppression of the action of pepsin which is the enzyme that exacerbates ulceration due to the presence of acid.

Biological Half-LifeSome reports have shown that after absorption, most body potassium exchanges rapidly with a half-life of less than 7 hours.
FDA Pharmacological Classification · 2건

POTASSIUM BICARBONATE

Osmotic Laxative [EPC]; Potassium Compounds [CS]; Potassium Salt [EPC]; Increased Large Intestinal Motility [PE]; Osmotic Activity [MoA]; Inhibition Large Intestine Fluid/Electrolyte Absorption [PE]

Absorption, Distribution and Excretion · 2건

Potassium bicarbonate intake is done mainly in the small intestine in which approximately 90% of the potassium will be absorbed by passive diffusion.

Approximately 90% of the exogenous potassium consumed is lost in the urine while the other 10% is excreted in feces and a very small amount can be found in the sweat. The excreted potassium is freely filtered by the glomerulus of the kidney.

용도 및 제조

Uses · 3건

CIR ingredient: Potassium Bicarbonate

Used in baking powders and as a potassium supplement; [Merck Index] Used in soft drinks, antacids, and fire extinguishers; [Hawley] Active pesticide product registrations in the US; [NPIRS] Approved for use as food additive in the EU; Active ingredient (85%) of the foliar fungicide Armicarb 85SP; [ExPub: EFSA]

Farming (Pesticides) [Category: Industry]

U.S. Production2023: 4,000,000 - <5,500,000 lb;2022: 1,000,000 - <5,000,000 lb;2021: 1,000,000 - <5,000,000 lb;2020: 1,000,000 - <5,000,000 lb
Consumer UsesNot Known or Reasonably Ascertainable;Fire extinguishing agent;Soil amendments (fertilizers);Cleaning agent;pH regulating agent;Surfactant (surface active agent);Processing aids not otherwise specified
Industry Uses · 1건

Flavoring and nutrient;Swelling agent;Processing aids not otherwise specified;Surfactant (surface active agent);pH regulating agent;Cleaning agent;Fire extinguishing agent;Soil amendments (fertilizers);Not Known or Reasonably Ascertainable;Intermediate

Household ProductsInformation on 6 consumer products that contain Potassium bicarbonate in the following categories is provided:;• Inside the Home;• Landscaping/Yard;• Pesticides
Use Classification · 6건

EPA Safer Chemical Functional Use Classes -> Processing Aids and Additives

Safer Chemical Classes -> Green circle - The chemical has been verified to be of low concern

Food additives

Food Additives -> ACIDITY_REGULATOR; LEAVENING_AGENT; RAISING_AGENT -> JECFA Functional Classes

Food Additives -> ACIDITY_REGULATOR; LEAVENING_AGENT; RAISING_AGENT -> JECFA Functional Classes

Plastics -> Other stabilisers

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1,176건

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