제일인산나트륨 수화물

인산나트륨,일염기,모노수화물 · 제일인산나트륨수화물 · 인산나트륨,일염기,모노수화물(SODIUMPHOSPHATE,MONOBASIC,MONOHYDRATE) · PHOSPHATE BUFFER · Sodium dihydrogen phosphate monohydrate · POTASSIUM PHOSPHATE BUFFER · PH 7 BUFFER · Phosphate buffered

https://huagongshe.com/ko/chemical/516949

식별자 및 물리적 특성

CAS No.	10049-21-5
분자식	H4NaO5P
평균 분자량	137.99 g/mol
단동위원소 질량	137.9694045 g/mol
SMILES	O.O=P([O-])(O)O.[Na+]
InChIKey	BBMHARZCALWXSL-UHFFFAOYSA-M
PubChem CID	516949
ChEBI	CHEBI:114249
EC No.	600-102-0
DTXSID	DTXSID6073994
현지명	제일인산나트륨 수화물

화학 및 물리적 성질

극성 표면적	81.6
수소 결합 공여자 수	3
수소 결합 수용자 수	5
회전 가능 결합 수	0
무거운 원자 수	7
형식 전하	0
복잡도	61
Physical Description	Dry PowderWhite odorless solidSlightly deliquescent[Merck Index] White hygroscopic crystals[Sigma-Aldrich MSDS]
녹는점	100°C -H₂O
끓는 점	399 °C
밀도	2,04 g/cm3
저장 조건	Store at +5°C to +30°C.
용해도	H2O: 1 M, 투명, 무색
물리적 상태	고체
pKa(산도 계수)	7.21
색상	흰색 반투명
냄새	냄새 없는
pH	4.1-4.5 (25℃, 50mg/mL in H2O)
용해도	물에 용해됨에탄올, 에테르 및 클로로포름에 용해되지 않습니다.
Merck	14,8660
InChI	1S/Na.H3O4P.H2O/c1-5(2,3)4/h(H3,1,2,3,4)1H2/q+1/p-1
InChIKey	BBMHARZCALWXSL-UHFFFAOYSA-M
SMILES	[Na+].[H]O[H].OP(O)([O-])=O
LogP(분배 계수)	-2.148 (est)
EPA	Monosodium phosphate monohydrate (10049-21-5)
Absorption	≤0.01 at 260nm≤0.01 at 280nm

화학적 성질

Anhydrous salt: white crystalline powder; slightly hygroscopic; forms sodium acid pyrophosphate, Na2H2P2O7 on heating above 225°C and sodium metaphosphate (NaPO3)n at about 350 to 400°C; very soluble in water, aqueous solution acidic. Monohydrate: white orthorhombic crystals or granules; density 2.04 g/cm3 ; loses its water of crystallization at 100°C; very soluble in water, pH of 1% solution 4.5; insoluble in alcohol. Dihydrate: large transparent crystals; orthorhombic bisphenoidal structure; density 1.915 g/cm 3 ; decomposes at 60°C; very soluble in water; insoluble in alcohol.

안전 및 규제

GHS 분류	This chemical does not meet GHS hazard criteria for 76.9% (40 of 52) of all reports.WarningH315 (21.2%): Causes skin irritation [Warning Skin corrosion/irritation]H319 (21.2%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]H335 (21.2%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposureRespiratory tract irritation]P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 52 reports by companies from 6 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.Reported as not meeting GHS hazard criteria per 40 of 52 reports by companies.There are 4 notifications provided by 12 of 52 reports by companies with hazard statement code(s).Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.
규제 정보	Chemical: Phosphoric acid, monosodium salt, monohydratePhosphoric acid, monosodium salt, monohydrate is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Phosphoric acid, monosodium salt, monohydrate are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)Monosodium dihydrogen phosphate: Does not have an individual approval but may be used under an appropriate group standard
기타 안전 정보	IMAP assessments - Phosphoric acid, monosodium salt, monohydrate: Human health tier I assessment
유해성 요약	May cause irritation[Sigma-Aldrich MSDS] See Sodium phosphate, monobasic.
Hazard Classes and Categories	Skin Irrit. 2 (21.2%)Eye Irrit. 2 (21.2%)STOT SE 3 (21.2%)
수질 위해 등급(WGK)

용도

개요

Sodium Phosphate Monobasic Monohydrate is a reagent with very high buffering capacity widely used in molecular biology, biochemistry and chromatography. it can be used as a buffer to adjust pH. In medicine, it is sometimes used as a stimulant laxative before certain operations and medical procedures. Sodium Phosphate Monobasic Monohydrate is often used in foods and in water treatment. It is used as sequestrant, emulsifier, mordant in dyeing, reagent and buffer in foods and analytical chemistry. It is applied as a fireproofing agent and for weighting silk in tanning. It is employed in manufacturing of enamels, ceramics, detergents, boiler compounds, in soldering and brazing instead of borax. Monobasic sodium phosphate is used in baking powders, acid cleansers, electroplating, as a dry acidulant, and in treating boiler water.

용도

Sodium Phosphate Monobasic Monohydrate is often used in foods and in water treatment. it can be used as a buffer to adjust pH. In medicine, it is sometimes used as a stimulant laxative before certain operations and medical procedures.

일반 설명

Useful in conjuction with sodium phosphate, dibasic (Cat. No. 567550) in the preparation of biological buffers(absorbance: ≤0.01 at 260 nm and 280 nm).

제조 및 합성 방법

제조 방법

Monobasic sodium phosphate can be prepared by partial neutralization of phosphoric acid with sodium hydroxide in equimolar amounts: H3PO4+ NaOH →NaH2PO4+ H2O It also can be made by treating disodium hydrogen phosphate with phosphoric acid in proper stoichiometric amount: Na2HPO4+ H3PO4→2NaH2PO4

생산 방법

Monobasic sodium phosphate is prepared by adding phosphoric acid to a hot, concentrated solution of disodium phosphate until the liquid ceases to form a precipitate with barium chloride. This solution is then concentrated and the monobasic sodium phosphate is crystallized.