아이오딘산나트륨
나트륨모노요오드화물 · 나트륨요오드화물(NAI) · 소요오딘 · 아이오딘산나트륨 · 아이오딘화나트륨(요오드화나트륨) · 요오두릴 · 요오드화나트륨 · 아이오딘화나트륨(요오드화나트륨)(SODIUMIODIDE)
식별자 및 물리적 특성
| CAS No. | 7681-82-5 |
|---|---|
| 분자식 | INa |
| 평균 분자량 | 149.8942 g/mol |
| 단동위원소 질량 | 149.89424 g/mol |
| SMILES | [I-].[Na+] |
| InChIKey | FVAUCKIRQBBSSJ-UHFFFAOYSA-M |
| PubChem CID | 5238 |
| ChEMBL | CHEMBL1644695 |
| ChEBI | CHEBI:33167 |
| EC No. | 231-679-3 |
| DTXSID | DTXSID2041125 |
| 현지명 | 아이오딘산나트륨 |
화학 및 물리적 성질
| 극성 표면적 | 0 |
|---|---|
| 수소 결합 공여자 수 | 0 |
| 수소 결합 수용자 수 | 1 |
| 회전 가능 결합 수 | 0 |
| 무거운 원자 수 | 2 |
| 형식 전하 | 0 |
| 복잡도 | 2 |
| pH | 8-9.56-9 (50g/l, H2O, 20℃) |
| 냄새 | ODORLESS |
| 맛 | SALINE, SOMEWHAT BITTER TASTE |
| 밀도 | 3.673.67 g/cm³3.667 @25 °C |
| Color/Form | COLORLESS, CUBIC CRYSTALSWHITE CRYSTALS OR GRANULESWHITE POWDER |
| 용해도 | SolubleSOLUBILITY (G/100 CC SOLVENT): 184 G IN WATER @ 25 °C302 G IN WATER @ 100 °C42.57 G IN ALCOHOL @ 25 °C39.9 G IN ACETONE @ 25 °C1 G SOL IN 1 ML GLYCEROLSolubility in water, g/100ml at 25 °C: 184물: 용해될 수 있음(lit.) |
| 끓는 점 | Decomposes1304 °C1304 °C @760 [mm Hg]1300 °C |
| 녹는점 | 651651 °C660 °C661 °C (lit.) |
| 증기압 | 1 MM HG @ 767 °C1 [mm Hg] @767 °C1 hPa (767 °C) |
| 굴절률 | INDEX OF REFRACTION: 1.7745 |
| Physical Description | LiquidCBIDry PowderWet SolidWhite odorless deliquescent solidTurned brown by air[Merck Index] Colorless to white hygroscopic solid[ICSC] White odorless crystalline powder[MSDSonline]COLOURLESS-TO-WHITE HYGROSCOPIC CRYSTALS OR WHITE POWDER. TURNS BROWN ON EXPOSURE TO AIR. |
| Stability/Shelf Life | IT IS MADE SLIGHTLY ALKALINE TO RENDER IT MORE STABLE |
| 증기 밀도 | >1 (vs air) |
| 인화점 | 1300-1304°C |
| 저장 조건 | Store at +5°C to +30°C. |
| pKa(산도 계수) | 0.067[at 20 ℃] |
| 물리적 상태 | 염주 |
| 비중 | 3.67 |
| 색상 | 하얀색 |
| 용해도 | 184g/100mL(25℃) |
| 비열 | Cp(crystal): 0.35 J/(g·K), at 25℃ |
| Merck | 14,8631 |
| 유전율 | 7.2800000000000002 |
| 안정성 | 흡습성 |
| 화장품 원료 기능 | 항균 |
| InChI | 1S/HI.Na/h1H/q+1/p-1 |
| InChIKey | FVAUCKIRQBBSSJ-UHFFFAOYSA-M |
| SMILES | [Na+].[I-] |
| LogP(분배 계수) | -1.301 at 25℃ |
| NIST | Sodium iodide(7681-82-5) |
| EPA | Sodium iodide (7681-82-5) |
안전 및 규제
| GHS 분류 | This chemical does not meet GHS hazard criteria for 7.9% (39 of 495) of reports.DangerH315 (70.9%): Causes skin irritation [Warning Skin corrosion/irritation]H319 (72.7%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]H335 (16.8%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposureRespiratory tract irritation]H372 (42.8%): Causes damage to organs through prolonged or repeated exposure [Danger Specific target organ toxicity, repeated exposure]H400 (61.8%): Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard]H411 (10.1%): Toxic to aquatic life with long lasting effects [Hazardous to the aquatic environment, long-term hazard]P260, P261, P264, P264+P265, P270, P271, P273, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P391, P403+P233, P405, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 495 reports by companies from 36 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.Reported as not meeting GHS hazard criteria per 39 of 495 reports by companies.There are 35 notifications provided by 456 of 495 reports by companies with hazard statement code(s).Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. |
|---|---|
| 규제 정보 | Chemical: Sodium iodide (NaI)Sodium iodide (NaI) is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Sodium iodide (NaI) are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)Status: Active Update: 05-04-2023 https://echa.europa.eu/registration-dossier/-/registered-dossier/5959Status: Active Update: 12-01-2023 https://echa.europa.eu/registration-dossier/-/registered-dossier/5847Status: Active Update: 18-02-2020 https://echa.europa.eu/registration-dossier/-/registered-dossier/25025Sodium iodide: Does not have an individual approval but may be used under an appropriate group standard |
용도
용도
Sodium iodide is widely used for halide exchange (Finkelstein reaction), for example in the conversion of an alkyl chloride, allyl chloride and arylmethyl chloride into their respective iodides, which are precursors for pharmaceutical and fine chemical products. They are used to ehnance the efficiency of the formation of Wittig adducts from less reactive chlorides and bromides. Appropriate prepartions find use as a nutrient supplement. Sodium iodide is used as the precursor to the control agent in ab initio emulsion polymerization. Sodium iodide finds use in the determination of dissolved oxygen in the modified Winkler method, synthesis of the fluorescent dye coppersensor-1 (CS1) for imaging labile copper pools in biological samples, and the cleavage of esters, lactones, carbamates and ethers in combination with chlorotrimethylsilane.
일반 설명
Sodium iodide is an inorganic salt. Mixture of chlorotrimethylsilane/sodium iodide in acetonitrile is a useful reagent for the cleavage of esters, lactones, carbamates and ethers.
제조 및 합성 방법
제조 방법
Sodium iodide is prepared by adding hydriodic acid or an acidic iodide solution to a solution of sodium hydroxide or sodium carbonate, followed by evaporation and crystallization: NaOH + HI → NaI + H2OThe solution is filtered to remove any impurities prior to its evaporation and crystallization.