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기본 정보
- CAS
82854-37-3- 표준 SMILES
C[C@@H]1O[C@@H](O[C@@H]2[C@@H](O)[C@H](OCCc3ccc(O)c(O)c3)O[C@H](CO[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)[C@H]2OC(=O)/C=C/c2ccc(O)c(O)c2)[C@H](O)[C@H](O)[C@H]1O- InChIKey
FSBUXLDOLNLABB-ISAKITKMSA-N- 분자식
- C35H46O20
- 평균 분자량
- 786.733 g/mol
- 단동위원소 질량
- 786.25824387
이름 및 식별자
- 우선 이름
- Echinacoside
- IUPAC
- 2-(3,4-Dihydroxyphenyl)ethyl 6-deoxy-alpha-L-mannopyranosyl-(1->3)-[beta-D-glucopyranosyl-(1->6)]-4-O-[(2E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]-beta-D-glucopyranoside
- 영어명
- ECHINACOSIDE
- 분자식
- C35H46O20
- 분자량
- 786.73
이름 및 동의어
Cistanche tubulosaEchicosideEchinacoside, froM Cistanche deserticola Y.C.Maβ-D-Glucopyranoside, 2-(3,4-dihydroxyphenyl)ethyl O-6-deoxy-α-L-mannopyranosyl-(1→3)-O-[β-D-glucopyranosyl-(1→6)]-, 4-[3-(3,4-dihydroxyphenyl)-2-propenoate]beta-d-eEchinosideECHINACOSIDEEchinacosidewPurpureaside CEchinacoside (P)
데이터베이스 식별자
- CAS
82854-37-3- PubChem CID
- 5281771
- DTXSID
DTXSID0033469- ChEMBL
CHEMBL393090、CHEMBL510539- ChEBI
CHEBI:4745- UNII
- I04O1DT48T
- EC Number
- 617-397-7
- Nikkaji
- J2.701.456I、J362.655E
물성
물리화학적 성질
- 끓는 점
- 1062.7 · 1062.7±65.0 °C(Predicted)
- 밀도
- 1.66 · 1.66±0.1 g/cm3(Predicted)
- 저장 조건
- 2 · Inert atmosphere,2-8°C
- 용해도
- 60 · DMSO:60.0(Max Conc. mg/mL);76.26(Max Conc. mM)DMSO:PBS (pH 7.2) (1:9):0.1(Max Conc. mg/mL);0.13(Max Conc. mM)DMF:30.0(Max Conc. mg/mL);38.13(Max Conc. mM)Ethanol:52.5(Max Conc. mg/mL);66.73(Max Conc. mM)Water:24.36(Max Conc. mg/mL);30.96(Max Conc. mM)
- 물리적 상태
- 가루
- 산도 계수 (pKa)
- 8.43 · 8.43±0.20(Predicted)
- 색상
- White-beige
- BRN
- 4778612 · 4778612
- 안정성
- 흡습성
- 주요 응용
- 대사체학비타민, 기능성 식품 및 천연 제품
- InChIKey
- FSBUXLDOLNLABB-ISAKITKMSA-N
- LogP
- 0.14 · 0.140 (est)
화학적 성질
White powder
안전 및 규제
안전 정보는 참고용이며, 공급업체의 물질안전보건자료(SDS), 관련 법규 및 전문가 평가를 대체하지 않습니다.
안전 데이터
- wgk
- 3
- rtecs
- LZ5786500
- HS 번호
- 29389090
- safety_code
- 24/25
- 스토리지 클래스
- 11 - Combustible Solids
화학 및 산업
응용 분야
개요Echinacoside is a phenylethanoid glycoside that has been found in Echinacea and has diverse biological activities. It scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH; ) radicals (EC50 = 6.6 μM in a cell-free assay). Echinacoside (10 μg/ml) inhibits hydrogen peroxide-induced production of reactive oxygen species (ROS) and apoptosis in PC12 cells. It reduces increases in plasma alanine aminotransferase (ALT), TNF-α, IL-1β, IL-16, and IL-10 levels and hepatocyte apoptosis induced by LPS/D-galactosamine in a mouse model of acute liver injury when administered at a dose of 60 mg/kg. Echinacoside (20 mg/kg per day for 15 days) prevents loss of dopaminergic neurons in the substantia nigra pars compacta and decreases in striatal dopamine and 3,4-dihydroxyphenylacetic acid (DOPAC) levels in a mouse model of MPTP-induced Parkinson''s disease. It also improves motor performance in the rotarod test in the same model.
용도Echinacoside Ethanolate is a caffeic acid glycoside, known for its neuroprotective, antiinflammatory and anti-oxidative activities. Also an anti[proliferative towards hypoxia influenced pulmonary artery smooth muscle cells.
공급사100 곳
北京华美互利生物化工010-56205725 · [email protected]
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山西玉宁生物科技有限公司13623677056 · [email protected]
南京普怡生物科技有限公司13814510036 · [email protected]
成都埃法生物科技有限公司028-028-85142057 19983342022 · [email protected]
成都彼样生物科技有限公司18108052721 · [email protected]
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