Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HCID 5283113생성일: 2026년 11월 4일
9-Oxo-15S-hydroxy-5Z,8(12),13E,17Z-prostatetraenoic acid
PGB3 · PROSTAGLANDIN B3 · DQRGQQAJYRBDRP-UNBCGXALSA-N · 9-Oxo-15s-hydroxy-prosta-5z,8(12),13e,17z-tetraen-1-oic acid · (5Z,13E,15S,17Z)-15-Hydroxy-9-oxoprosta-5,8(12),13,17-tetraen-1-oic acid · 7-[2-[(3S)-3-hydroxyocta-1,5-dienyl]-5-oxocyclopenten-1-yl]hept-5-enoic acid · Prosta-5,8(12),13,17-tetraen-1-oic acid, 15-hydroxy-9-oxo-, (5Z,13E,15S,17Z)-
https://huagongshe.com/ko/chemical/5283113
식별자 및 물리적 특성
| CAS No. | 36614-32-1 |
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| 분자식 | C20H28O4 |
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| 평균 분자량 | 332.44 g/mol |
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| 단동위원소 질량 | 332.19875938 g/mol |
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| SMILES | CC/C=C\C[C@H](O)/C=C/C1=C(C/C=C\CCCC(=O)O)C(=O)CC1 |
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| InChIKey | DQRGQQAJYRBDRP-UNBCGXALSA-N |
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| PubChem CID | 5283113 |
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| ChEBI | CHEBI:134511 |
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| DTXSID | DTXSID901372554 |
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화학 및 물리적 성질
| 끓는 점 | 548.8±50.0 °C(Predicted) |
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| 밀도 | 1.135±0.06 g/cm3(Predicted) |
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| 용해도 | DMF: >75 mg/ml (from PGB2)DMSO: >50 mg/ml (from PGB2)Ethanol: >100 mg/ml (from PGB2)PBS pH 7.2: >2 mg/ml (from PGB2) |
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| pKa(산도 계수) | 4.74±0.10(Predicted) |
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안전 및 규제
| 신호 어 | Danger |
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| 유해·위험 문구 | 암호 유해·위험 문구 위험 등급 범주 신호 어 그림 문자 P- 코드 H225 |
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용도
개요
Prostaglandin B3 (PGB3) is a non-enzymatic dehydration product resulting from the treatment of Prostaglandin E3 (PGE3) with strong base. In a structure-activity binding study to determine the affinity of various prostaglandins to human PPARγ, PGB3 exhibited a Ki value greater than 1 mM. In contrast, PGB1 and PGB2 showed significantly higher affinity for PPARγ, with Ki values of 26 and 77 μM, respectively, the same assay.
