올레인산아미드

Oleamide

HCID 5283387CAS 301-02-0

기본 정보

표준 SMILES
CCCCCCCC/C=C\CCCCCCCC(N)=O
InChIKey
FATBGEAMYMYZAF-KTKRTIGZSA-N
분자식
C18H35NO
평균 분자량
281.5 g/mol
단동위원소 질량
281.27186474

이름 및 식별자

우선 이름
Oleamide
IUPAC
(Z)-octadec-9-enamide
현지명
올레인산아미드
영어명
Oleamide
분자식
C18H35NO
분자량
281.48

이름 및 동의어

Oleamide301-02-0Oleic acid amideOleylamideOleyl amide(Z)-octadec-9-enamideAdogen 739-Octadecenamide, (9Z)-Crodamide OCrodamide ORSlip-ezeArmoslip CP
이름 더 보기
올레인산아미드올레아마이드(9Z)-9-옥타데센아마이드(Z)-9-옥타데칸아마이드(Z)-옥타데크-9-엔아마이드9-시스-올레아마이드시스-9-옥타데센오아마이드올레산 아마이드ODA9-OCTADECENAMIDEOLEAMIDCIS-9-OCTADECENAMIDE9-Octadecenamide,(Z)-(9Z)-9-Octadecenamide
(Z)-9-OCTADECENAMIDE9Z-octadecenamideArmid O9,10-octadecenamide7L25QK8BWONSC-26987CHEBI:116314RefChem:856476

데이터베이스 식별자

CAS
301-02-0
PubChem CID
5283387
DTXSID
DTXSID6027137
ChEMBL
CHEMBL15927
ChEBI
CHEBI:116314
UNII
7L25QK8BWO
EC Number
206-103-9
Nikkaji
J36.613G

물성

구조 계산 물성

XLogP
6.6
극성 표면적
43.1 Ų
수소 결합 공여자 수
1
수소 결합 수용자 수
1
회전 가능 결합 수
15
무거운 원자 수
20

실험 및 물리화학적 성질

Density0.94
Color/FormIVORY-COLORED POWDER
SolubilityINSOL IN WATER; SOL IN ETHER, HOT ALCOHOL
Melting Point · 2건

76 °C

102 - 104 °C

Vapor Pressure0.0000012 [mmHg]
Physical Description · 3건

Large Crystals; Dry Powder; Liquid; Dry Powder; Large Crystals; Other Solid; Dry Powder; Large Crystals

Ivory-colored solid; [HSDB]

Solid

물리화학적 성질

녹는점
70 °C · 70°C
끓는 점
433.3 · 433.3±24.0 °C(Predicted)
밀도
0.94 g/cm3 · 0.94 g/cm3
저장 조건
-20 °C · -20°C
용해도
클로로포름(50mg/ml), 에탄올(100mM), DMSO(~14mg/ml) 및 DMF(~14mg/ml)에 용해됩니다.
산도 계수 (pKa)
16.61 · 16.61±0.40(Predicted)

화학적 성질

White Powder

안전 및 규제

GHS 분류

GHS Classification · 6건

This chemical does not meet GHS hazard criteria for 42.7% (470 of 1101) of reports.

Warning

H315 (12.1%): Causes skin irritation [Warning Skin corrosion/irritation];H319 (12.1%): Causes serious eye irritation [Warning Serious eye damage/eye irritation];H335 (12.1%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation];H413 (40.2%): May cause long lasting harmful effects to aquatic life [Hazardous to the aquatic environment, long-term hazard]

P261, P264, P264+P265, P271, P273, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 1101 reports by companies from 10 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.;Reported as not meeting GHS hazard criteria per 470 of 1101 reports by companies.;There are 7 notifications provided by 631 of 1101 reports by companies with hazard statement code(s).;Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

유해성 정보

Regulatory Information · 3건

Chemical: 9-Octadecenamide, (Z)-

9-Octadecenamide, (9Z)- is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of 9-Octadecenamide, (9Z)- are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

9-Octadecenamide, (9Z)-: Does not have an individual approval but may be used under an appropriate group standard

Other Safety InformationIMAP assessments - 9-Octadecenamide, (Z)-: Human health tier I assessment
Hazards Summary · 1건

Contact urticarial reaction reported within 20 minutes of open patch test; Emergency treatment: Irritants; [HSDB] Causes mild skin and eye irritation in rabbits; Not considered sensitizing to human skin; [IUCLID] Causes changes in motor activity and excitement in acute intraperitoneal toxic-dose studies of rats and mice; [RTECS] A skin and strong eye irritant; May cause an allergic skin reaction; [Aldrich MSDS]

Hazard Classes and Categories · 2건

Skin Irrit. 2 (12.1%);Eye Irrit. 2 (12.1%);STOT SE 3 (12.1%);Aquatic Chronic 4 (40.2%)

Serious eye damage/eye irritation - Category 2B

독성 정보

Human Toxicity ExcerptsOPEN PATCH TEST WITH OLEYLAMIDE (AMIDE OF OLEIC ACID) 0.1% IN ETHANOL ELICITED A STRONG URTICARIAL REACTION IN 20 MIN.

규제 정보

Regulatory Information · 3건

Chemical: 9-Octadecenamide, (Z)-

9-Octadecenamide, (9Z)- is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of 9-Octadecenamide, (9Z)- are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

9-Octadecenamide, (9Z)-: Does not have an individual approval but may be used under an appropriate group standard

안전 데이터

wgk
1
tsca
TSCA listed
HS 번호
29241990
risk_code
36/37/38-43
hazard_code
Xi
safety_code
26-36-37

화학 및 산업

약리 정보

MeSH Pharmacological Classification · 2건

Substances used in the processing or storage of foods or animal feed including ANTIOXIDANTS; FOOD PRESERVATIVES; FOOD COLORING AGENTS; FLAVORING AGENTS; ANTI-INFECTIVE AGENTS; EXCIPIENTS and other similarly used substances. Many of the same substances are used as PHARMACEUTIC AIDS.

Drugs used to induce drowsiness or sleep or to reduce psychological excitement or anxiety.

Cellular LocationsExtracellular;Membrane

용도 및 제조

Uses · 6건

Used as a slip and anti-block agent for extrusion of polyethylene and an additive to wax, printing inks, lubricating oils, and cosmetics; [HSDB] Used as a rubber additive, anti-static agent, dispersion aid, and mold release agent; [IUCLID]

Molding and Core Making [Category: Foundry]

SLIP-AGENT FOR EXTRUSION OF POLYETHYLENE; WAX ADDITIVE; INK ADDITIVE; COSMETICS

SLIP & ANTIBLOCK AGENT FOR PLASTICS-ESP POLYETHYLENE FILM

LUBRICATING OIL ADDITIVE

PRINTING INK ADDITIVE

U.S. Exports · 2건

(1979) No Data

(1981) No Data

U.S. Imports · 2건

(1979) No Data

(1981) No Data

U.S. Production · 3건

2023: 7,000,000 - <8,500,000 lb;2022: 10,000,000 - <25,000,000 lb;2021: 10,000,000 - <25,000,000 lb;2020: 10,000,000 - <25,000,000 lb

(1980) 2.27X10+9 GRAMS (ESTIMATE)

(1981) PROBABLY GREATER THAN 6.81X10+6 GRAMS

Consumer UsesLubricating agent;Anti-adhesive/cohesive;Surface modifier
Industry UsesAnti-adhesive/cohesive;Lubricating agent;Anti-slip agent;Adhesion/cohesion promoter;Anti-scaling agent;Surface modifier

응용 분야

용도Oleamide has been used as a supplement in glucose and galactose media to prevent the rescue of galactose-induced Leigh syndrome (LS).

일반 설명Oleamideis a lipid or a brain fatty acid, that is found in the CSF (cerebrospinal fluid). It is originally obtained from the cerebrospinal fluid of cats, that are sleep-deprived.

공급사50 곳

梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
湖南长沙恒昌化工有限公司0731-85070388 13217318550
河北创海生物科技有限公司+86-86-13131129325 · [email protected]
Hebei Yanxi Chemical Co., Ltd.+86-17531190177 · [email protected]

추가 설명

정의ChEBI: A fatty amide derived from oleic acid.

관련 반응

3건

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