기본 정보
- 표준 SMILES
CCCCCCCC/C=C\CCCCCCCC(N)=O- InChIKey
FATBGEAMYMYZAF-KTKRTIGZSA-N- 분자식
- C18H35NO
- 평균 분자량
- 281.5 g/mol
- 단동위원소 질량
- 281.27186474
이름 및 식별자
- 우선 이름
- Oleamide
- IUPAC
- (Z)-octadec-9-enamide
- 현지명
- 올레인산아미드
- 영어명
- Oleamide
- 분자식
- C18H35NO
- 분자량
- 281.48
이름 및 동의어
이름 더 보기
데이터베이스 식별자
- CAS
301-02-0- PubChem CID
- 5283387
- DTXSID
DTXSID6027137- ChEMBL
CHEMBL15927- ChEBI
CHEBI:116314- UNII
- 7L25QK8BWO
- EC Number
- 206-103-9
- Nikkaji
- J36.613G
물성
구조 계산 물성
- XLogP
- 6.6
- 극성 표면적
- 43.1 Ų
- 수소 결합 공여자 수
- 1
- 수소 결합 수용자 수
- 1
- 회전 가능 결합 수
- 15
- 무거운 원자 수
- 20
- 형식 전하
- 0
- 복잡도
- 236
실험 및 물리화학적 성질
Melting Point
76 °C
102 - 104 °C
Physical Description
Large Crystals; Dry Powder; Liquid; Dry Powder; Large Crystals; Other Solid; Dry Powder; Large Crystals
Ivory-colored solid; [HSDB]
Solid
Kovats Retention Index
2375;2397
3265
물리화학적 성질
- 녹는점
- 70 °C · 70°C
- 끓는 점
- 433.3 · 433.3±24.0 °C(Predicted)
- 밀도
- 0.94 g/cm3 · 0.94 g/cm3
- 저장 조건
- -20 °C · -20°C
- 용해도
- 클로로포름(50mg/ml), 에탄올(100mM), DMSO(~14mg/ml) 및 DMF(~14mg/ml)에 용해됩니다.
- 산도 계수 (pKa)
- 16.61 · 16.61±0.40(Predicted)
- 물리적 상태
- Solid
- 색상
- 흰색에서 황백색까지
- 수용성
- 물에 불용성.
- 안정성
- 2 · 제공된 대로 구매일로부터 2년 동안 안정적입니다. DMSO 또는 에탄올 용액은 -20°C에서 최대 1개월 동안 보관할 수 있습니다.
- 화장품 원료 기능
- 불투명화점도 조절
- InChI
- 1S/C18H35NO/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20/h9-10H,2-8,11-17H2,1H3,(H2,19,20)/b10-9-
- InChIKey
- FATBGEAMYMYZAF-KTKRTIGZSA-N
- SMILES
- CCCCCCCC\C=C/CCCCCCCC(N)=O
- LogP
- 6.882 · 6.882 (est)
- NIST
- 9 · 9-Octadecenamide, (z)-(301-02-0)
- EPA
- Oleamide (301-02-0)
화학적 성질
White Powder
안전 및 규제
GHS 분류
GHS Classification
This chemical does not meet GHS hazard criteria for 42.7% (470 of 1101) of reports.
Warning
H315 (12.1%): Causes skin irritation [Warning Skin corrosion/irritation];H319 (12.1%): Causes serious eye irritation [Warning Serious eye damage/eye irritation];H335 (12.1%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation];H413 (40.2%): May cause long lasting harmful effects to aquatic life [Hazardous to the aquatic environment, long-term hazard]
P261, P264, P264+P265, P271, P273, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 1101 reports by companies from 10 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.;Reported as not meeting GHS hazard criteria per 470 of 1101 reports by companies.;There are 7 notifications provided by 631 of 1101 reports by companies with hazard statement code(s).;Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.
유해성 정보
Regulatory Information
Chemical: 9-Octadecenamide, (Z)-
9-Octadecenamide, (9Z)- is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of 9-Octadecenamide, (9Z)- are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)
9-Octadecenamide, (9Z)-: Does not have an individual approval but may be used under an appropriate group standard
Hazards Summary
Contact urticarial reaction reported within 20 minutes of open patch test; Emergency treatment: Irritants; [HSDB] Causes mild skin and eye irritation in rabbits; Not considered sensitizing to human skin; [IUCLID] Causes changes in motor activity and excitement in acute intraperitoneal toxic-dose studies of rats and mice; [RTECS] A skin and strong eye irritant; May cause an allergic skin reaction; [Aldrich MSDS]
Hazard Classes and Categories
Skin Irrit. 2 (12.1%);Eye Irrit. 2 (12.1%);STOT SE 3 (12.1%);Aquatic Chronic 4 (40.2%)
Serious eye damage/eye irritation - Category 2B
독성 정보
규제 정보
Regulatory Information
Chemical: 9-Octadecenamide, (Z)-
9-Octadecenamide, (9Z)- is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of 9-Octadecenamide, (9Z)- are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)
9-Octadecenamide, (9Z)-: Does not have an individual approval but may be used under an appropriate group standard
안전 데이터
- wgk
- 1
- tsca
- TSCA listed
- HS 번호
- 29241990
- risk_code
- 36/37/38-43
- hazard_code
- Xi
- safety_code
- 26-36-37
- 기존화학 물질
- KE-26431
- Hazard Classifications
- Aquatic Chronic 4
- 스토리지 클래스
- 11 - Combustible Solids
- 유해 물질 데이터
- 301-02-0(Hazardous Substances Data)
화학 및 산업
약리 정보
MeSH Pharmacological Classification
Substances used in the processing or storage of foods or animal feed including ANTIOXIDANTS; FOOD PRESERVATIVES; FOOD COLORING AGENTS; FLAVORING AGENTS; ANTI-INFECTIVE AGENTS; EXCIPIENTS and other similarly used substances. Many of the same substances are used as PHARMACEUTIC AIDS.
Drugs used to induce drowsiness or sleep or to reduce psychological excitement or anxiety.
용도 및 제조
Uses
Used as a slip and anti-block agent for extrusion of polyethylene and an additive to wax, printing inks, lubricating oils, and cosmetics; [HSDB] Used as a rubber additive, anti-static agent, dispersion aid, and mold release agent; [IUCLID]
Molding and Core Making [Category: Foundry]
SLIP-AGENT FOR EXTRUSION OF POLYETHYLENE; WAX ADDITIVE; INK ADDITIVE; COSMETICS
SLIP & ANTIBLOCK AGENT FOR PLASTICS-ESP POLYETHYLENE FILM
LUBRICATING OIL ADDITIVE
PRINTING INK ADDITIVE
U.S. Exports
(1979) No Data
(1981) No Data
U.S. Imports
(1979) No Data
(1981) No Data
U.S. Production
2023: 7,000,000 - <8,500,000 lb;2022: 10,000,000 - <25,000,000 lb;2021: 10,000,000 - <25,000,000 lb;2020: 10,000,000 - <25,000,000 lb
(1980) 2.27X10+9 GRAMS (ESTIMATE)
(1981) PROBABLY GREATER THAN 6.81X10+6 GRAMS
General Manufacturing Information
Plastics Material and Resin Manufacturing;Paint and Coating Manufacturing;Adhesive Manufacturing;All Other Chemical Product and Preparation Manufacturing;Rubber Product Manufacturing;Custom Compounding of Purchased Resins;Petroleum Lubricating Oil and Grease Manufacturing;Synthetic Rubber Manufacturing;Plastics Product Manufacturing;Wholesale and Retail Trade
9-Octadecenamide, (9Z)-: ACTIVE
ADOGEN /IS/ TRADEMARK FOR SERIES OF FATTY NITROGEN CHEM INCL AMINES, AMIDES... AVAIL IN VARIOUS GRADES FOR SPECIFIC APPLICATIONS IN FABRIC SOFTENERS, ORE SEPARATION, DETERGENTS, PETROLEUM ADDITIVES, CORROSION INHIBITORS, BACTERICIDES, PRINTING INKS, ANTIBLOCK & SLIP AGENTS... /ADOGEN/
SLIP-EZE /IS/ TRADEMARK FOR A SPECIALLY PREPARED FATTY ACID AMIDE. USED AS SLIP ADDITIVE & AS INTERNAL MOLD-RELEASE ADDITIVE TO POLYETHYLENE.
응용 분야
용도Oleamide has been used as a supplement in glucose and galactose media to prevent the rescue of galactose-induced Leigh syndrome (LS).
일반 설명Oleamideis a lipid or a brain fatty acid, that is found in the CSF (cerebrospinal fluid). It is originally obtained from the cerebrospinal fluid of cats, that are sleep-deprived.
상·하류 제품 정보
상류 원료
하류 제품
공급사50 곳
추가 설명
정의ChEBI: A fatty amide derived from oleic acid.
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