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83199-47-7[2H]C([2H])([2H])C([2H])(CCC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C)C([2H])([2H])[2H]HVYWMOMLDIMFJA-IFAPJKRJSA-N83199-47-7DTXSID50415625CHEBI:172955White to Off-White Solid
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개요Cholesterol-d7 is intended for use as an internal standard for the quantification of cholesterol by GC- or LC-MS. Cholesterol is a major sterol produced in mammalian cells that is required for cell viability and proliferation. It is a component of mammalian cell membranes that interacts with membrane phospholipids, sphingolipids, and proteins to influence their behavior. Cholesterol is a precursor of steroid hormones, bile acids, and the active form of vitamin D. Impaired cholesterol homeostasis is related to development of various diseases including fatty liver, diabetes, gallstones, dyslipidemia, atherosclerosis, heart attack, and stroke.
용도Cholesterol-d7 is a labelled Cholesterol (C432501). Cholesterol-d7 is the principal sterol of the higher animals. Cholesterol-d7 was found in all body tissues, especial in the brain, spinal cord, and in animal fats or oils. Cholesterol-d7 is the main constituent of gallstones. Cholesterol-d7 can be used as a practical tracer for studies of cholesterol metabolism in humans.
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