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기본 정보
- CAS
192705-80-9- 표준 SMILES
CCN(CC)CCCCNc1ncc2cc(-c3c(Cl)cccc3Cl)c(NC(=O)NC(C)(C)C)nc2n1- InChIKey
MKVMEJKNLUWFSQ-UHFFFAOYSA-N- 분자식
- C26H35Cl2N7O
- 평균 분자량
- 532.52 g/mol
- 단동위원소 질량
- 531.2280141
이름 및 식별자
- 우선 이름
- 1-Tert-butyl-3-[6-(2,6-dichlorophenyl)-2-[4-(diethylamino)butylamino]pyrido[2,3-d]pyrimidin-7-yl]urea
- IUPAC
- N-tert-Butyl-N'-[6-(2,6-dichlorophenyl)-2-{[4-(diethylamino)butyl]amino}pyrido[2,3-d]pyrimidin-7-yl]urea
- 영어명
- N-[6-(2,6-Dichlorophenyl)-2-[[4-(diethylamino)butyl]amino]pyrido[2,3-d]pyrimidin-7-yl]-N'-(1,1-dimethylethyl)urea
- 분자식
- C26H35Cl2N7O
- 분자량
- 532.51
이름 및 동의어
PD 161570PF-1480232PD-161570PF-1480232PD-161570, 10 mM in DMSO1-(tert-Butyl)-3-(6-(2,6-dichlorophenyl)-2-((4-(diethylamino)butyl)amino)pyrido[2,3-d]pyrimidi1-Tert-butyl-3-[6-(2,6-dichloro-phenyl)-2-(4-diethylaMino-butylaMino)pyrido[2,3-d]pyriMidin-7-yl]ureaN-[6-(2,6-Dichlorophenyl)-2-[[4-(diethylamino)butyl]amino]pyrido[2,3-d]pyrimidin-7-yl]-N'-(1,1-dimethylethyl)ureaUrea, N-[6-(2,6-dichlorophenyl)-2-[[4-(diethylamino)butyl]amino]pyrido[2,3-d]pyrimidin-7-yl]-N'-(1,1-dimethylethyl)-Inhibitor,Fibroblast growth factor receptor,HER1,kinases,autophosphorylation,PDGFR,PD161570,FGFR,Src,inhibit,TGF-β Receptor,ATP-competitive,Epidermal growth factor receptor,tyrosine,Platelet-derived growth factor receptor,disease,EGFR,anti-cancer,angiogenesis,ErbB-1,FGFR1,Transforming growth factor beta receptors,cardiovascular,anti-proliferation,PD-161570
데이터베이스 식별자
- CAS
192705-80-9- PubChem CID
- 5328135
- DTXSID
물성
물리화학적 성질
- 녹는점
- 215 · 215-230C
- 밀도
- 1.249 · 1.249±0.06 g/cm3(Predicted)
- 저장 조건
- Store at RT
- 용해도
- 10 mg/mL · DMSO: >10mg/mL
- 물리적 상태
- 가루
- 산도 계수 (pKa)
- 9.82 · 9.82±0.43(Predicted)
- 색상
- 흰색에서 황백색까지
- InChIKey
- MKVMEJKNLUWFSQ-UHFFFAOYSA-N
- SMILES
- CCN(CC)CCCCNc1ncc2cc(c(NC(=O)NC(C)(C)C)nc2n1)-c3c(Cl)cccc3Cl
화학적 성질
Off-White Solid
안전 및 규제
안전 정보는 참고용이며, 공급업체의 물질안전보건자료(SDS), 관련 법규 및 전문가 평가를 대체하지 않습니다.
안전 데이터
- wgk
- 3
- ridadr
- UN 2811 6.1 / PGIII
- risk_code
- 25-36/37/38
- hazard_code
- T
- safety_code
- 26-45
- Hazard Classifications
- Acute Tox. 3 OralEye Irrit. 2Skin Irrit. 2STOT SE 3
- 스토리지 클래스
- 6.1C - Combustible acute toxic Cat.3toxic compounds or compounds which causing chronic effects
화학 및 산업
응용 분야
용도A novel FGF-1 receptor tyrosine kinase inhibitor which has been shown to effectively suppress constitutive phosphorylation of the FGF-1 receptor in human ovarian carcinoma cells.
공급사38 곳
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
上海优宁维生物科技股份有限公司15921930842 15921930842 · [email protected]
上海毕得医药科技股份有限公司400-1647117 13681763483 · [email protected]
浙江珲达生物科技有限公司0571-89903022 18679456698 · [email protected]
Nantong HI-FUTURE Biology Co., Ltd.+86-18051384581 · [email protected]
武汉易泰科技有限公司上海分公司18930552037 · [email protected]
MedBio脉铂医药021-69568360 18916172912 · [email protected]
銳迪國際科技有限公司18024082417 · [email protected]
济南德迈医药科技有限公司18669728830 15806766175 · [email protected]
学研惠（武汉）科技有限公司15727060112 · [email protected]
BOC Sciences1-631-485-4226; 16314854226 · [email protected]
TOKYO CHEMICAL INDUSTRY CO., LTD.03-36680489 · [email protected]
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