Prostaglandin E1

개요Alprostadil은 또한 노르 에피네프린의 신경 방출을 방지하여 노르 에피네프린의 혈관 수축 작용을 길항 할 수 있으며 비 아드레날린, 비 콜린성 혈관 확장 성 신경 전달 물질의 작용을 향상시킬 수 있습니다. ED 치료에서 알프로 스타 틸은 섬유주 평활근을 이완시키고 해면 동맥과 그 가지를 확장시킴으로써 발기를 유도합니다.

용도Alprostadil (Prostglandin E1)은 성인 남성의 발기 부전 (ED) 치료에 사용됩니다.

개요Prostaglandin E1 is an endogenous prostaglandin with vasodilatory, anti-platelet, and anti-hypertensive activities. It is in clinical use for the treatment of erectile dysfunction and the emergency management of infants with patent ductus arteriosus. It has also been used in the treatment of peripheral arterial occlusive disease (PAD).

용도A primary Prostaglandin; easily crystallized from purified biological extracts. Vasodilator (peripheral)

일반 설명PGE1, Alprostadil (Prostin VR Pediatric), is a naturally occurring prostaglandin that has found particular use in maintaining a patent (opened) ductus arteriosus in infants with congenital defects that restrict pulmonary or systemic blood flow. Alprostadil must be administered intravenously continually at a rate of approximately 0.1 μg/kg/min to maintain the patency of the ductus arteriosus until corrective surgery can be performed. Up to 80% of circulating alprostadil may be metabolized in a single pass through the lungs. Because apnea has been observed in 10% to 12% of neonates with congenital heart defects, this product should be administered only when ventilatory assistance is immediately available. Other commonly observed side effects include decreased arterial blood pressure, which should be monitored during infusion; inhibited platelet aggregation, which might aggravate bleeding tendencies; and diarrhea.