템포스

템포스 · 테메포스 · ABATE · temefos · Abat · Difos · lypor · Ecopro

식별자 및 물리적 특성

CAS No.	3383-96-8
분자식	C16H20O6P2S3
평균 분자량	466.5 g/mol
단동위원소 질량	465.98972462 g/mol
SMILES	COP(=S)(OC)Oc1ccc(Sc2ccc(OP(=S)(OC)OC)cc2)cc1
InChIKey	WWJZWCUNLNYYAU-UHFFFAOYSA-N
PubChem CID	5392
ChEMBL	CHEMBL1355821
ChEBI	CHEBI:38954
EC No.	222-191-1
DTXSID	DTXSID1032484
현지명	템포스

화학 및 물리적 성질

XLogP	6
극성 표면적	145
수소 결합 공여자 수	0
수소 결합 수용자 수	9
회전 가능 결합 수	10
무거운 원자 수	27
형식 전하	0
복잡도	474
SpringerMaterials Properties	Fusion temperature
농약	InsecticidesActive substance -> EU Pesticides database: Not approvedPesticides -> Organophosphate InsecticidesPesticide (Temephos) -> USDA PDB
LogP(분배 계수)	log Kow = 5.96
밀도	1.32 (NIOSH, 2024) - Denser than waterwill sink1.3 g/cu cm1.3 g/cm³1.3200
Color/Form	Colorless crystalsWhite, crystalline solid or liquid (above 87 degrees F) [Note: Technical grade is a brown, viscous liquid].
용해도	Insoluble (NIOSH, 2024)Soluble in common organic solvents such as diethyl ether, aromatic and chlorinated hydrocarbons.Soluble in acetonitrile, carbon tetrachloride, ether, tolueneIn hexane, 9.6 g/LIn water, 9.0X10-6 g/L at 10 °C2.7X10-4 g/L at 20 °C7.0X10-4 g/L at 30 °CIn water, 0.27 mg/L at 25 °CDMSO : ≥ 100 mg/mL (214.38 mM)
인화점	ABATE 4-E 167 °F (Closed Cup)ABATE 6-E 109 °F (Closed Cup)ABATE 200-E 113 °F (Closed Cup)ABATE 500-E 142 °F (Closed Cup)
끓는 점	248 to 257 °F at 760 mmHg (Decomposes) (NIOSH, 2024)248-257 °F (decomposes)518.5±60.0 °C(Predicted)
Decomposition	When heated to decomposition it emits toxic /phosphorus oxide and sulfur oxide/ fumes.120-125 °C
녹는점	87 °F (NIOSH, 2024)30.0-30.5 °C30 °C30-31°C
증기압	7e-08 mmHg at 77 °F (NIOSH, 2024)0.00000007 [mmHg]Vapor pressure at 25 °C: negligible0.00000007 mmHg at 77 °F(77 °F): 0.00000007 mmHg9.5×10-6Pa (20-25 °C)
Physical Description	Temephos appears as white crystalline solid or liquid (above 87 °F). Used as an insecticide. Technical grade is a viscous brown liquid. (NIOSH, 2024)White, crystalline solid or liquid (above 87 degrees F). [insecticide] [Note: Technical grade is a viscous, brown liquid.][NIOSH]COLOURLESS OR WHITE CRYSTALS OR LIQUID.White, crystalline solid or liquid (above 87 °F).White, crystalline solid or liquid (above 87 °F). [insecticide] [Note: Technical grade is a viscous, brown liquid.]
저장 조건	2-8°C
물리적 상태	고체
색상	Colorless to light yellow
용해도	0.003g/100mL
Merck	13,9214
BRN	1896901
헨리 상수	1.7×100 mol/(m3Pa) at 25℃, Barcelo and Hennion (1997)
주요 응용	농업환경
InChI	InChI=1S/C16H20O6P2S3/c1-17-23(25,18-2)21-13-5-9-15(10-6-13)27-16-11-7-14(8-12-16)22-24(26,19-3)20-4/h5-12H,1-4H3
InChIKey	WWJZWCUNLNYYAU-UHFFFAOYSA-N
SMILES	P(=S)(OC)(OC)OC1C=CC(SC2C=CC(OP(=S)(OC)OC)=CC=2)=CC=1
NIST	Temefos(3383-96-8)
EPA	Temephos (3383-96-8)

안전 및 규제

GHS 분류	DangerH302 (61.5%): Harmful if swallowed [Warning Acute toxicity, oral]P260, P261, P262, P264, P270, P271, P273, P280, P301+P317, P302+P352, P304+P340, P316, P317, P319, P321, P330, P361+P364, P362+P364, P391, P405, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 78 reports by companies from 7 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.H311: Toxic in contact with skin [Danger Acute toxicity, dermal]
규제 정보	Hazard Traits - Developmental ToxicityNeurotoxicity2002/2076Temephos: HSNO Approval: HSR002880 Approved with controlsThe New Jersey Worker and Community Right to Know Act requires public and private employers to provide information about hazardous substances at their workplaces. (N.J.S.A. 34:5A-1 et. seq.)
기타 안전 정보	IMAP assessments - Phosphorothioic acid, O,O'-(thiodi-4,1-phenylene) O,O,O',O'-tetramethyl ester: Environment tier I assessment
운송 라벨(DOT)	Class 9
화재 위험	Excerpt from ERG Guide 171 [Substances (Low to Moderate Hazard)]:Combustible. Liquid formulations containing organic solvents may be flammable. Gives off irritating or toxic fumes (or gases) in a fire.
화재 가능성	Combustible. Liquid formulations containing organic solvents may be flammable.
건강 유해성	Excerpt from NIOSH Pocket Guide for Temephos:
유해성 요약	Classified as slightly toxic with an LD50 of 5 gm/kg for the 2% powder formulation[EXTOXNET] The average of two baseline respective cholinesterase activity determinations three days apart, with no exposures to enzyme inhibiting pesticides for at least 30 days, is recommended for each worker prior to exposure to cholinesterase inhibitors because of large inter-individual differences in published baseline values. To be established at least once a year. Removal from workplace exposures is recommended until the cholinesterase activity returns to within 20% of baseline. [TLVs and BEIs]
반응성 그룹	Esters, Sulfate Esters, Phosphate Esters, Thiophosphate Esters, and Borate Esters

용도

개요

Abate is the trade name for Temephos, the known organophosphate larvicide. Abate is used to treat water infested with disease-carrying fleas and control mosquito, midge, and black fly larvae. Abate quickly controls mosquito and other insect populations because it kills insect larvae before they mature, and the residual activity of abate prevents insect populations. On decomposition, abate produces oxides of carbon, phosphorous, and sulphur. Exposures to abate in workplaces cause adverse health effects (refer to Temephos for details).

용도

Temephos is an organophosphate larvicide used to treat water infested with disease-carrying insects.

일반 설명

White crystalline solid or liquid. Boiling point 87°F. Used as an insecticide. Technical grade is a viscous brown liquid.