1-Boc-3-hydroxypiperidine (HCID 545699)

이름 및 식별자

우선 이름: 1-Boc-3-hydroxypiperidine
IUPAC: tert-butyl 3-hydroxypiperidine-1-carboxylate
영어명: 1-Boc-3-hydroxypiperidine
분자식: C10H19NO3
분자량: 201.26

이름 및 동의어

1-Boc-3-hydroxypiperidine85275-45-2DTXSID40337963RefChem:430083DTXCID00289050628-428-9tert-butyl 3-hydroxypiperidine-1-carboxylate1-Boc-3-piperidinol1-n-boc-3-hydroxy-piperidineMFCD020939381-tert-Butoxycarbonyl-3-hydroxy piperidinen-boc-3-hydroxypiperidine

이름 더 보기

N-BOC-3-PIPERIDINOLRARECHEM EM WB 0260Ibrutinib Impurity 57Ibrutinib Impurity 126BOC-3-HYDROXYPIPERIDINEN-BOC-3-HYDOXYPIPERIDINEN-Boc-3-hydroxypiperidin

N-(tert-Butoxycarbonyl)-3-piperidinol(r)-n-boc-3-hydroxypiperidineboc-(r,s)-3-hydroxypiperidine1-(tert-Butoxycarbonyl)-3-hydroxypiperidine1-Piperidinecarboxylic acid, 3-hydroxy-, 1,1-dimethylethyl esterN-Boc-3-Hydroxy piperidine3-hydroxypiperidine-1-carboxylic acid tert-butyl ester3-hydroxy-piperidine-1-carboxylic acid tert-butyl ester

데이터베이스 식별자

CAS: 85275-45-2
PubChem CID: 545699
DTXSID: DTXSID40337963
UNII: VZK3X8HTC8
EC Number: 628-428-9
Nikkaji: J527.164I

물성

구조 계산 물성

XLogP: 1
극성 표면적: 49.8 Å²
수소 결합 공여자 수: 1
수소 결합 수용자 수: 3
회전 가능 결합 수: 2
무거운 원자 수: 14
형식 전하: 0
복잡도: 210

물리화학적 성질

녹는점: 65 · 65-67°C
끓는 점: 292.3 · 292.3±33.0 °C(Predicted)
밀도: 1.107 · 1.107±0.06 g/cm3(Predicted)
저장 조건: Sealed in dry,Room Temperature
물리적 상태: powder to crystal
산도 계수 (pKa): 14.74 · 14.74±0.20(Predicted)
색상: 흰색에서 거의 흰색
BRN: 4180859 · 4180859
InChI: InChI=1S/C10H19NO3/c1-10(2,3)14-9(13)11-6-4-5-8(12)7-11/h8,12H,4-7H2,1-3H3
InChIKey: UIJXHKXIOCDSEB-UHFFFAOYSA-N
SMILES: N1(C(OC(C)(C)C)=O)CCCC(O)C1

화학적 성질

White solid

안전 및 규제

GHS 분류

GHS Classification · 5건

Warning

H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]；H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]；H335 (97.9%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 48 reports by companies from 8 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.；Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

유해성 정보

Hazard Classes and CategoriesSkin Irrit. 2 (100%)；Eye Irrit. 2 (100%)；STOT SE 3 (97.9%)

안전 데이터

wgk: 3
HS 번호: 29339900
risk_code: 36/37/38-20/21/22
hazard_code: Xi
safety_code: 26-36-36/37/39
위험 등급: IRRITANT
기존화학 물질: 2015-3-7009

화학 및 산업

응용 분야

용도It is a pharmaceutical intermediate.

상·하류 제품 정보

상류 원료

하류 제품

(3R)-1-Boc-3-(4-aMino-3-iodo-1H-pyrazolo[3,4-d]pyriMidin-1-yl)piperidine 3-(4-Chlorophenoxy)piperidine 1-Boc-3-피페리돈 tert-부틸3-포르밀프로필메틸카바메이트

공급사50 곳

梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]

上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]

南京一化生物科技有限公司13429882898; 13429882898

INTATRADE GmbH+49 3493/605464 · [email protected]

T&W GROUP021-61551611 13296011611 · [email protected]

연결된 노트

불러오는 중…

1-Boc-3-hydroxypiperidine

기본 정보