CAS 57044-25-4 (+)-Glycidol (HCID 5460455)

개요

(R)-glycidol is a glycidol. It is functionally related to a (R)-1,2-epoxypropane. It is an enantiomer of a (S)-glycidol.

이름 및 식별자

우선 이름: (+)-Glycidol
IUPAC: [(2R)-oxiran-2-yl]methanol
현지명: (R)-(+)-글리시돌
영어명: (R)-(+)-Glycidol
분자식: C3H6O2
분자량: 74.08

이름 및 동의어

(R)-Glycidol57044-25-4(R)-Oxiranemethanol(+)-Glycidol(2R)-oxiran-2-ylmethanol(R)-(+)-2,3-Epoxy-1-propanolCHEBI:18664DTXSID40904710R-2,3-epoxy-1-propanolRefChem:70304DTXCID701333819404-660-4

이름 더 보기

(R)-(+)-글리시돌(R)-(+)-글리시돌((R)-(+)-GLYCIDOL)R-2,3-에폭시-1-프로판올EOS-60676R-Glycidoe(R)-(+)-GL(R)-GLYCIDOL,99%(r)-oxiranemethano

(R)-Oxiran-2-ylmethanol(R)-(+)-Glycidol[(2R)-oxiran-2-yl]methanol(R)-3-hydroxy-1,2-epoxypropaneMFCD00074873(2R)-2-oxiranylmethanolOxiranemethanol, (2R)-R-Glycidol

데이터베이스 식별자

CAS: 57044-25-4
PubChem CID: 5460455
DTXSID: DTXSID40904710
ChEBI: CHEBI:18664
EC Number: 404-660-4、629-598-7
Nikkaji: J425.695F

물성

구조 계산 물성

XLogP: -0.9
극성 표면적: 32.8 Å²
수소 결합 공여자 수: 1
수소 결합 수용자 수: 2
회전 가능 결합 수: 1
무거운 원자 수: 5
형식 전하: 0
복잡도: 35.9

실험 및 물리화학적 성질

SpringerMaterials PropertiesSchoenflies notation

물리화학적 성질

끓는 점: 56 · 56-57 °C11 mm Hg(lit.)
밀도: 1.116 g/mL · 1.116 g/mL at 20 °C(lit.)
굴절률: 20 · n20/D 1.43(lit.)
인화점: 178 °F · 178 °F
저장 조건: -20 °C · -20°C
수용성: Completely miscible in water
용해도: 클로로포름 (약간 용해됨), DMSO (약간 용해됨)
산도 계수 (pKa): 14.62 · 14.62±0.10(Predicted)
색상: 무색~연황색
BRN: 79782 · 79782
안정성: 수분에 민감한
InChI: 1S/C3H6O2/c4-1-3-2-5-3/h3-4H,1-2H2/t3-/m1/s1
InChIKey: CTKINSOISVBQLD-GSVOUGTGSA-N
SMILES: OC[C@@H]1CO1
NIST: Oxiranemethanol, (R)-(57044-25-4)

화학적 성질

Colorless to light yellow liqui

안전 및 규제

GHS 분류

GHS Classification · 6건

Danger

H242: Heating may cause a fire [Danger Self-reactive substances and mixtures; Organic peroxides]

P203, P210, P234, P235, P240, P260, P261, P264, P270, P271, P280, P301+P317, P301+P330+P331, P302+P352, P302+P361+P354, P304+P340, P305+P354+P338, P316, P317, P318, P321, P330, P362+P364, P363, P370+P378, P403, P403+P233, P405, P410, P411, P420, and P501 (click each P-code to see the statement)

Danger

H242 (100%): Heating may cause a fire [Danger Self-reactive substances and mixtures; Organic peroxides]

P203, P210, P234, P235, P240, P260, P264, P270, P271, P280, P284, P301+P317, P301+P330+P331, P302+P352, P302+P361+P354, P304+P340, P305+P354+P338, P316, P317, P318, P320, P321, P330, P362+P364, P363, P370+P378, P403, P403+P233, P405, P410, P411, P420, and P501 (click each P-code to see the statement)

유해성 정보

Regulatory Information · 2건

Hazard Traits - Carcinogenicity; Reproductive Toxicity

Status: Active Update: 10-11-2008 https://echa.europa.eu/registration-dossier/-/registered-dossier/8465

Hazard Classes and Categories · 5건

Self-react. C (100%)

Acute Tox. 4 (100%)

Self-reactive substance or mixture - type C

Flammable liquids - Category 4

Self-react. C ****

안전 데이터

wgk: 3
rtecs: RR0508000
ridadr: UN 2922 8/PG 2
HS 번호: 29109000
risk_code: 45-60-2-21/22-23-34-68-41-37/38
hazard_code: T,E
safety_code: 53-45-36/37/39-26
포장분류: Ⅲ
위험 등급: 6.1
F 고인화성물질: 10-21
Hazard Classifications: Acute Tox. 2 InhalationAcute Tox. 4 DermalAcute Tox. 4 OralCarc. 1BEye Dam. 1Muta. 2Repr. 1BSelf-react. CSkin Corr. 1BSTOT SE 3
스토리지 클래스: 5.2 - Organic peroxides and self-reacting hazardous materials

화학 및 산업

응용 분야 · 2건

용도(R)-(+)-Glycidol may be used in the following synthesis:heteroarylpropane-2,3-diols, useful for combinatorial oligomer synthesisenantiomerically pure (2S,3S)- and (2S,3R)-threoninol and -hydroxyphenylalaninol2-amino-1,4-anhydro-pentitol and 3-amino-1,5-anhydro-4-deoxy-hexitol with the arabino configuration(S)-4-tosyloxymethyl-2-oxazolidinone, required for the synthesis of protected amino alcohol derivatives1-(S)-[3-hydroxy-2-(phosphonomethoxy)propyl]cytosine [(S)-HPMPC]chiral building block used to construct an epoxyvinyl iodide intermediate in a synthesis of a furanocembrane, a marine natural product

일반 설명Enantioselective esterification of (R)-(+)-glycidol with n-butyric acid in organic media using hybrid gel-entrapped lipase on Celite has been reported.