기본 정보
- CAS
83928-66-9- 표준 SMILES
CC1(C)CC(=O)N(CCCCN2CCN(c3ncccn3)CC2)C(=O)C1.Cl- InChIKey
DGOCVISYYYQFEP-UHFFFAOYSA-N- 분자식
- C19H30ClN5O2
- 평균 분자량
- 395.9 g/mol
- 단동위원소 질량
- 395.2088029
개요
Gepirone hydrochloride is the hydrochloride salt of gepirone. It is a prescription medicine used to treat adults with a certain type of depression called major depressive disorder. It has a role as an antidepressant, an anxiolytic drug and a serotonergic agonist. It contains a gepirone(1+).
이름 및 식별자
- 우선 이름
- Gepirone monohydrochloride
- IUPAC
- 4,4-dimethyl-1-[4-(4-pyrimidin-2-ylpiperazin-1-yl)butyl]piperidine-2,6-dione;hydrochloride
- 영어명
- Gepirone hydrochloride
- 분자식
- C19H30ClN5O2
- 분자량
- 395.9268
이름 및 동의어
gepirone monohydrochlorideRefChem:142962GEPIRONE HYDROCHLORIDEGepirone HCl83928-66-9TravivoExxuaGepirone ERGepirone hydrochloride [USAN]BMY 13805-1Org 33062TGFK07AD
이름 더 보기
RRSYY(Avadomide)-6GepironeHydrochloride2,6-Piperidinedione,4,4-dimethyl-1-[4-[4-(2- pyrimidinyl)-1-piperazinyl]butyl]-,monohydrochloride2,6-Piperidinedione, 4,4-dimethyl-1-[4-[4-(2-pyrimidinyl)-1-piperazinyl]butyl]-, hydrochloride (1:1)
ORG-3306280C9L8EP6VCHEMBL1204187VarizaBMY-13805-14,4-Dimethyl-1-(4-(4-(pyrimidin-2-yl)piperazin-1-yl)butyl)piperidine-2,6-dione hydrochlorideGepirone hydrochloride (USAN)3,3-Dimethyl-1-(4-(4-(2-pyrimidinyl)-1-piperazinyl)butyl)glutarimide monohydrochloride
데이터베이스 식별자
- CAS
83928-66-9- PubChem CID
- 55190
- DTXSID
DTXSID30232812- ChEMBL
CHEMBL1204187- ChEBI
CHEBI:229646
물성
구조 계산 물성
- 극성 표면적
- 69.6 Ų
- 수소 결합 공여자 수
- 1
- 수소 결합 수용자 수
- 6
- 회전 가능 결합 수
- 6
- 무거운 원자 수
- 27
- 형식 전하
- 0
- 복잡도
- 476
실험 및 물리화학적 성질
Human Drugs
FDA approved drugs -> Active ingredient
FDA approved drugs -> Active ingredient
물리화학적 성질
- 녹는점
- 192.5 · 192.5-195.5 °C
- 용해도
- 2 O: · H2O: 2 mg/mL, clear
- 물리적 상태
- powder
- 색상
- white to beige
- InChI
- InChI=1S/C19H29N5O2.ClH/c1-19(2)14-16(25)24(17(26)15-19)9-4-3-8-22-10-12-23(13-11-22)18-20-6-5-7-21-18;/h5-7H,3-4,8-15H2,1-2H3;1H
- InChIKey
- DGOCVISYYYQFEP-UHFFFAOYSA-N
- SMILES
- N1(CCCCN2CCN(C3=NC=CC=N3)CC2)C(=O)CC(C)(C)CC1=O.[H]Cl
안전 및 규제
안전 정보는 참고용이며, 공급업체의 물질안전보건자료(SDS), 관련 법규 및 전문가 평가를 대체하지 않습니다.
안전 데이터
- 신호 어
- Warning
- 유해·위험 문구
- 암호 유해·위험 문구 위험 등급 범주 신호 어 그림 문자 P- 코드 H302
화학 및 산업
약리 정보
MeSH Pharmacological Classification
Mood-stimulating drugs used primarily in the treatment of affective disorders and related conditions. Several MONOAMINE OXIDASE INHIBITORS are useful as antidepressants apparently as a long-term consequence of their modulation of catecholamine levels. The tricyclic compounds useful as antidepressive agents (ANTIDEPRESSIVE AGENTS, TRICYCLIC) also appear to act through brain catecholamine systems. A third group (ANTIDEPRESSIVE AGENTS, SECOND-GENERATION) is a diverse group of drugs including some that act specifically on serotonergic systems.
Agents that alleviate ANXIETY, tension, and ANXIETY DISORDERS, promote sedation, and have a calming effect without affecting clarity of consciousness or neurologic conditions. ADRENERGIC BETA-ANTAGONISTS are commonly used in the symptomatic treatment of anxiety but are not included here.
Endogenous compounds and drugs that bind to and activate SEROTONIN RECEPTORS. Many serotonin receptor agonists are used as ANTIDEPRESSANTS; ANXIOLYTICS; and in the treatment of MIGRAINE DISORDERS.
응용 분야
용도Tranquilizer.
공급사32 곳
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济南启源生物科技有限公司18766124282; 18766124282 · [email protected]
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