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이소프로테놀히드로클로라이드

(+-)-Isoproterenol hydrochloride

HCID 5807
노트반응
기본 정보개요이름 및 식별자물성안전 및 규제화학 및 산업관련 반응화합물 노트
부분 구조 검색유사 구조 찾기

기본 정보

CAS
51-30-9
표준 SMILES
CC(C)NCC(O)c1ccc(O)c(O)c1.Cl
InChIKey
IROWCYIEJAOFOW-UHFFFAOYSA-N
분자식
C11H17NO3.ClH
평균 분자량
247.72 g/mol
단동위원소 질량
247.0975211

개요

Isoproterenol hydrochloride is an odorless white crystalline powder. Slightly bitter taste. Aqueous solutions turn brownish-pink upon prolonged exposure to air. (NTP, 1992)

이름 및 식별자

우선 이름
(+-)-Isoproterenol hydrochloride
IUPAC
4-[1-hydroxy-2-(propan-2-ylamino)ethyl]benzene-1,2-diol;hydrochloride
현지명
이소프로테놀히드로클로라이드
영어명
Isoproterenol hydrochloride
분자식
C11H18ClNO3
분자량
247.72

이름 및 동의어

Isoprenaline hydrochloride51-30-9ISOPROTERENOL HYDROCHLORIDEAeroloneAerotrolVapo-IsoIsoproterenol HClAsthpulNorisodrine AerotrolDL-Isoproterenol hydrochloridedl-Isadrine hydrochlorideIsopropylarterenol hydrochloride
이름 더 보기
이소프로테놀히드로클로라이드ISOPRENALINE HCLTIMTEC-BB SBB003172dl-isadrinehydrochloridedl-isoprenalinehydrochloride-n-isopropyl-dl-noradrenalineHCl
Isoprenaline chlorideMistarelSuscardiaIsovon(+-)-Isoproterenol hydrochlorideIsoproterenol monohydrochloride(+-)-Isoprenaline hydrochlorideNCI-C55630

데이터베이스 식별자

CAS
51-30-9、949-36-0
PubChem CID
5807
DTXSID
DTXSID6025486
ChEMBL
CHEMBL1711
ChEBI
CHEBI:31453

물성

구조 계산 물성

극성 표면적
72.7 Ų
수소 결합 공여자 수
5
수소 결합 수용자 수
4
회전 가능 결합 수
4
무거운 원자 수
16
형식 전하
0
복잡도
187

실험 및 물리화학적 성질

Solubility · 2건

Soluble (NTP, 1992)

>37.2 [ug/mL] (The mean of the results at pH 7.4)

Human Drugs · 2건

FDA approved drugs -> Active ingredient

FDA approved drugs -> Active ingredient

Melting Point338 to 340 °F (NTP, 1992)
Physical DescriptionIsoproterenol hydrochloride is an odorless white crystalline powder. Slightly bitter taste. Aqueous solutions turn brownish-pink upon prolonged exposure to air. (NTP, 1992)

물리화학적 성질

녹는점
165 · 165-175 °C (dec.)(lit.)

안전 및 규제

안전 정보는 참고용이며, 공급업체의 물질안전보건자료(SDS), 관련 법규 및 전문가 평가를 대체하지 않습니다.

GHS 분류

GHS Classification · 4건

Warning

H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]

P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 41 reports by companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

유해성 정보

Other Safety InformationIMAP assessments - 1,2-Benzenediol, 4-[1-hydroxy-2-[(1-methylethyl)amino]ethyl]-, hydrochloride: Human health tier I assessment
Fire HazardsFlash point data for this chemical are not available. It is probably combustible. (NTP, 1992)
Health Hazards · 1건

SYMPTOMS: Symptoms of exposure to this compound may include tremors, nervous apprehension, palpitations of the heart, epigastric distress, cardiac arrhythmias, myocardial necrosis, cardiac arrest, tachycardia, headache, flushing of the skin, anginal pain, nausea, dizziness, weakness, and sweating. (NTP, 1992)

Reactive GroupAlcohols and Polyols
Reactivity Profile · 1건

An acid organic salt. Materials in this group are generally soluble in water. The resulting solutions contain moderate concentrations of hydrogen ions and have pH's of less than 7.0. They react as acids to neutralize bases. These neutralizations generate heat, but less or far less than is generated by neutralization of inorganic acids, inorganic oxoacids, and carboxylic acid. They usually do not react as either oxidizing agents or reducing agents but such behavior is not impossible.

Air and Water ReactionsMay be sensitive to exposure to air and light. (NTP, 1992). Water soluble.

화학 및 산업

약리 정보

FDA Pharmacological Classification · 2건

ISOPROTERENOL HYDROCHLORIDE

Adrenergic beta-Agonists [MoA]; beta-Adrenergic Agonist [EPC]

MeSH Pharmacological Classification · 4건

Drugs that selectively bind to and activate beta-adrenergic receptors.

Agents that cause an increase in the expansion of a bronchus or bronchial tubes.

Agents that have a strengthening effect on the heart or that can increase cardiac output. They may be CARDIAC GLYCOSIDES; SYMPATHOMIMETICS; or other drugs. They are used after MYOCARDIAL INFARCT; CARDIAC SURGICAL PROCEDURES; in SHOCK; or in congestive heart failure (HEART FAILURE).

Drugs that mimic the effects of stimulating postganglionic adrenergic sympathetic nerves. Included here are drugs that directly stimulate adrenergic receptors and drugs that act indirectly by provoking the release of adrenergic transmitters.

공급사8 곳

武汉易泰科技有限公司上海分公司18930552037 · [email protected]
北京绿百草科技发展有限公司010-61136123 · [email protected]
南京世洲生物科技有限公司13675144456 · [email protected]
Chongqing jooe co., ltd+86-15223382610 · [email protected]
陕西缔都医药化工有限公司029-029-81120477 17792793610 · [email protected]
金锦乐(湖南)化学有限公司18001959627(微信同号) 18001959627 · [email protected]
厦门盈融达化工有限公司+86-0592-6210733 · [email protected]
Dideu Industries Group Limited

관련 반응

5건
반응 기록 만들기
HRID 53100 반응식
HRID 53100반응물로uspto-grants-1997_04
HRID 726527 반응식
HRID 726527반응물로uspto-grants-1998_01
HRID 1379587 반응식
HRID 1379587반응물로uspto-grants-1997_09
HRID 1769224 반응식
HRID 1769224반응물로uspto-grants-1995_01
HRID 2256804 반응식
HRID 2256804반응물로uspto-grants-1997_08

화합물 노트

불러오는 중…

이 페이지에서기본 정보개요이름 및 식별자물성안전 및 규제화학 및 산업관련 반응화합물 노트
UNII
DIA2A74855
EC Number
200-089-8、213-438-4
Hazard Classes and CategoriesSkin Irrit. 2 (100%)

안전 및 보호

Fire FightingFires involving this material can be controlled with a dry chemical, carbon dioxide or Halon extinguisher. (NTP, 1992)
First Aid · 1건

EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.

Nonfire Spill Response · 1건

SMALL SPILLS AND LEAKAGE: If you spill this chemical, you should dampen the solid spill material with water, then transfer the dampened material to a suitable container. Use absorbent paper dampened with water to pick up any remaining material. Seal your contaminated clothing and the absorbent paper in a vapor-tight plastic bag for eventual disposal. Wash all contaminated surfaces with a soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned.

Personal Protective Equipment (PPE) · 1건

RECOMMENDED RESPIRATOR: Where the neat test chemical is weighed and diluted, wear a NIOSH-approved half face respirator equipped with an organic vapor/acid gas cartridge (specific for organic vapors, HCl, acid gas and SO2) with a dust/mist filter. (NTP, 1992)

독성 정보

Drug Induced Liver Injury · 6건

Drug Induced Liver Injury Rank (DILIrank 2.0)

Isoproterenol hydrochloride

vNo-DILI-concern

0

No match

DOI:10.1016/j.drudis.2016.02.015

안전 데이터

wgk
2
rtecs
DO1925000
risk_code
36/37/38
hazard_code
Xi
safety_code
26-36
F 고인화성물질
3-8-10
+86-29-81148696 +86-15129568250 · [email protected]