기본 정보
- CAS
52-62-0- 표준 SMILES
C[N+]1(CCCCC[N+]2(C)CCCC2)CCCC1.O=C([O-])[C@H](O)[C@@H](O)C(=O)O.O=C([O-])[C@H](O)[C@@H](O)C(=O)O- InChIKey
HSMKTIKKPMTUQH-WBPXWQEISA-L- 분자식
- C23H42N2O12
- 평균 분자량
- 538.6 g/mol
- 단동위원소 질량
- 538.27377478
개요
Pentolinium tartrate is the bitartrate salt of pentolinium. It has a role as an antihypertensive agent. It contains a pentolinium ion.
이름 및 식별자
- 우선 이름
- Pentolinium Tartrate
- IUPAC
- 1-methyl-1-[5-(1-methylpyrrolidin-1-ium-1-yl)pentyl]pyrrolidin-1-ium;bis((2R,3R)-2,3,4-trihydroxy-4-oxobutanoate)
이름 및 동의어
PENTOLINIUM TARTRATEAnsolysenPentolonium tartrateRecurylTensilestPentalinium tartrateTartrato de pentolonioTartrate de pentoloniumPentolonii tartrasPentapyrrolidium bitartrate953357GACYPentamethylene-1,5-bis(1'-methylpyrrolidinium tartrate)
이름 더 보기
NSC-759890CHEBI:55326pentolonio tartratopentolonium (cation)Tartrate, PentoliniumTartrate, PentoloniumRefChem:57597Pyrrolidinium, 1,1'-(1,5-pentanediyl)bis(1-methyl)-, salt with (R-(R*,R*))-2,3-dihydroxybutanedioic acid (1:2)
데이터베이스 식별자
- CAS
52-62-0- PubChem CID
- 5849
- ChEMBL
CHEMBL1318287- ChEBI
CHEBI:55326- UNII
- 953357GACY
물성
구조 계산 물성
- 극성 표면적
- 236 Ų
- 수소 결합 공여자 수
- 6
- 수소 결합 수용자 수
- 12
- 회전 가능 결합 수
- 10
- 무거운 원자 수
- 37
- 형식 전하
- 0
- 복잡도
- 347
실험 및 물리화학적 성질
Human Drugs
FDA approved drugs -> Active ingredient
FDA approved drugs -> Active ingredient
화학 및 산업
약리 정보
MeSH Pharmacological Classification
Drugs used in the treatment of acute or chronic vascular HYPERTENSION regardless of pharmacological mechanism. Among the antihypertensive agents are DIURETICS; (especially DIURETICS, THIAZIDE); ADRENERGIC BETA-ANTAGONISTS; ADRENERGIC ALPHA-ANTAGONISTS; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; CALCIUM CHANNEL BLOCKERS; GANGLIONIC BLOCKERS; and VASODILATOR AGENTS.
Agents having as their major action the interruption of neural transmission at nicotinic receptors on postganglionic autonomic neurons. Because their actions are so broad, including blocking of sympathetic and parasympathetic systems, their therapeutic use has been largely supplanted by more specific drugs. They may still be used in the control of blood pressure in patients with acute dissecting aortic aneurysm and for the induction of hypotension in surgery.
Drugs that bind to nicotinic cholinergic receptors (RECEPTORS, NICOTINIC) and block the actions of acetylcholine or cholinergic agonists. Nicotinic antagonists block synaptic transmission at autonomic ganglia, the skeletal neuromuscular junction, and at central nervous system nicotinic synapses.
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