팜퍼

O-디메틸-O-(파라-(디메틸숨팜오일)페닐)포스포로티오에이트 · 팜퍼 · O,O-디메틸-O-(파라-(디메틸술팜오일)페닐)포스포로티오에이트 · 와벡스 · 파모포스 · 팜포스 · 포스포로티오익산,O-(4-((디메틸아미노)술포닐)페닐)O,O-디메틸에스테르 · FAMOPHOS

https://huagongshe.com/ko/chemical/5859

식별자 및 물리적 특성

CAS No.	52-85-7
분자식	C10H16NO5PS2
평균 분자량	325.3 g/mol
단동위원소 질량	325.02075124 g/mol
SMILES	COP(=S)(OC)Oc1ccc(S(=O)(=O)N(C)C)cc1
InChIKey	JISACBWYRJHSMG-UHFFFAOYSA-N
PubChem CID	5859
ChEMBL	CHEMBL1525287
ChEBI	CHEBI:38677
EC No.	200-154-0
DTXSID	DTXSID7041966
현지명	팜퍼

화학 및 물리적 성질

XLogP	2.2
극성 표면적	106
수소 결합 공여자 수	0
수소 결합 수용자 수	7
회전 가능 결합 수	6
무거운 원자 수	19
형식 전하	0
복잡도	418
SpringerMaterials Properties	Fusion temperature
농약	Pesticides -> Organophosphate InsecticidesPesticide (Famphur) -> USDA PDB
LogP(분배 계수)	Oil/water partitioning coefficient: 2.23 (log)2.28
Color/Form	CRYSTALSColorless crystalline powder
용해도	Sparingly soluble in water. In aqueous isopropanol (45%) 23 g/kg (20 °C)in xylene 300 g/kg (5 °C)soluble in acetone, carbon tetrachloride, chloroform, cyclohexanone, dichloromethane, toluenesparingly soluble in aliphatic hydrocarbons
Animal Drugs	FDA approved animal drugs -> Active ingredient
Endocrine Disruptors	Potential endocrine disrupting compound
녹는점	52.5-53.5 °C53℃
증기압	0.00000136 [mmHg]3 x 10-5 Pa (est. 20 °C)
Physical Description	Famphur is a crystalline powder. Very toxic. Cholinesterase inhibitor. Restricted use as insecticide.Colorless solid[HSDB]
Stability/Shelf Life	STABLE /TECHNICAL/
Collision Cross Section	173.8 Å² [M+Na]+ [CCS Type: DTBuffer gas: N2Ionization: ESI+Dataset: TOXCASTSource Identifier: DTXSID7041966]182.13 Å² [M+Na]+169.47 Å² [M+H]+ [CCS Type: TWIonization: GC-APCI+]
끓는 점	394.2±52.0 °C(Predicted)
밀도	1.354±0.06 g/cm3(Predicted)
인화점	>100 °C
저장 조건	APPROX 4°C
물리적 상태	액체
용해도	5000(예상 20°C)
pKa(산도 계수)	-5.18±0.70(Predicted)
Merck	13,3963
BRN	2224254
InChI	1S/C10H16NO5PS2/c1-11(2)19(12,13)10-7-5-9(6-8-10)16-17(18,14-3)15-4/h5-8H,1-4H3
InChIKey	JISACBWYRJHSMG-UHFFFAOYSA-N
SMILES	COP(=S)(OC)Oc1ccc(cc1)S(=O)(=O)N(C)C
EPA	Famphur (52-85-7)

화학적 성질

Crystalline powder. Very soluble in chloroform and carbon tetrachloride; slightly soluble in water.

안전 및 규제

GHS 분류	DangerH300 (92.9%): Fatal if swallowed [Danger Acute toxicity, oral]P264, P264+P265, P270, P280, P301+P316, P302+P352, P305+P351+P338, P317, P321, P330, P332+P317, P337+P317, P362+P364, P405, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 42 reports by companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
규제 정보	The New Jersey Worker and Community Right to Know Act requires public and private employers to provide information about hazardous substances at their workplaces. (N.J.S.A. 34:5A-1 et. seq.)
기타 안전 정보	IMAP assessments - Phosphorothioic acid, O-[4-[(dimethylamino)sulfonyl]phenyl]O,O-dimethyl ester: Environment tier I assessment
운송 라벨(DOT)	Poison
화재 위험	Excerpt from ERG Guide 152 [Substances - Toxic (Combustible)]:
건강 유해성	Excerpt from ERG Guide 152 [Substances - Toxic (Combustible)]:
유해성 요약	A cholinesterase inhibitor[Hawley] Caused inhibition of cholinesterase activity in rats, birds, and livestock[HSDB] A highly toxic cholinesterase inhibitor[CAMEO] No adverse effects to fertility observed in cattleNo information found with regards to teratogenicity or effects on lactation[REPROTOX] The average of two baseline respective cholinesterase activity determinations three days apart, with no exposures to enzyme inhibiting pesticides for at least 30 days, is recommended for each worker prior to exposure to cholinesterase inhibitors because of large inter-individual differences in published baseline values. To be established at least once a year. Removal from workplace exposures is recommended until the cholinesterase activity returns to within 20% of baseline. [TLVs and BEIs]
FDA 요건	Famphur is used as a pour-on formulation for the control of cattle grubs and to reduce cattle lice infestation to be used at the rate of 1 ounce per 200 pounds body weight, not to exceed a total dosage of 4 ounces. Famphur is to be applied as soon as possible after heel fly activity ceases. Not to be usd on lactating dairy cows or dry dairy cows within 21 days of freshening calves less than 3 months old, animals stressed from castration over-excitement or dehorning, sick or convalescent animals. Animals may be dehydrated and under stress following shipment. Do not treat Brahman bulls.

용도

Insecticide.

일반 설명

Crystalline powder. Very toxic. Cholinesterase inhibitor. Restricted use as insecticide.