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하이드록시아세틸아미노플루오렌

Hydroxyacetylaminofluorene

HCID 5896
노트반응
기본 정보개요이름 및 식별자물성안전 및 규제화학 및 산업관련 반응화합물 노트
부분 구조 검색유사 구조 찾기

기본 정보

CAS
53-95-2
표준 SMILES
CC(=O)N(O)c1ccc2c(c1)Cc1ccccc1-2
InChIKey
SOKUIEGXJHVFDV-UHFFFAOYSA-N
분자식
C15H13NO2
평균 분자량
239.27 g/mol
단동위원소 질량
239.09462866

개요

N-hydroxy-2-acetylaminofluorene is a cream colored powder. (NTP, 1992)

이름 및 식별자

우선 이름
Hydroxyacetylaminofluorene
IUPAC
N-(9H-fluoren-2-yl)-N-hydroxyacetamide
현지명
하이드록시아세틸아미노플루오렌
영어명
Hydroxyacetylaminofluorene
분자식
C15H13NO2
분자량
239.27

이름 및 동의어

N-Hydroxy-2-acetamidofluorene53-95-2HydroxyacetylaminofluoreneN-Hydroxy-2-acetylaminofluoreneNohfaaN-HYDROXY-2-(ACETYLAMINO)FLUORENE2-HydroxyacetylaminofluoreneN-Hydroxy acetylaminofluoreneN-Hydroxy-acetylaminofluoreneCCRIS 338N-Hydroxy-2-fluorenylacetamideHydroxyfluorenylacetamide
이름 더 보기
하이드록시아세틸아미노플루오렌N-Hydroxy-AAFN-HYDROXY-2-AAF2-(Acetylhydroxyamino)-9H-fluoreneN-HYDROXY-N-(2-FLUORENYL)ACETAMIDEN-Fluoren-2-ylacetohydroxamic acidN-Acetyl-N-2-fluorenylhydroxylamineN-Hydroxy-2-acetylamino-9H-fluorene
2-N-Hydroxy-acetylaminofluoreneUNII-6AGD02HUQC6AGD02HUQCBRN 2654276DTXSID2020719AI3-50466NSC-46522CHEBI:17931

데이터베이스 식별자

CAS
53-95-2
PubChem CID

물성

구조 계산 물성

XLogP
2.7
극성 표면적
40.5 Ų
수소 결합 공여자 수
1
수소 결합 수용자 수
2
회전 가능 결합 수
1
무거운 원자 수
18
형식 전하
0
복잡도
330

실험 및 물리화학적 성질

Solubilityless than 1 mg/mL at 64 °F (NTP, 1992)
Melting Point277 to 279 °F (NTP, 1992)
Physical DescriptionN-hydroxy-2-acetylaminofluorene is a cream colored powder. (NTP, 1992)

물리화학적 성질

녹는점
140 · 140-143°C
끓는 점
381.93 °C · 381.93°C (rough estimate)
밀도
1.1198 · 1.1198 (rough estimate)
굴절률
1.55 · 1.5500 (estimate)
저장 조건
Refrigerator
용해도
DMSO(약간 용해됨), 메탄올(약간 용해됨)
물리적 상태
고체
색상
밝은 노란색에서 노란색까지
안정성
안정적인. 강한 산화제와 호환되지 않습니다.
EPA
-2 · N-Hydroxy-2-acetylaminofluorene (53-95-2)

화학적 성질

cream powder

안전 및 규제

안전 정보는 참고용이며, 공급업체의 물질안전보건자료(SDS), 관련 법규 및 전문가 평가를 대체하지 않습니다.

유해성 정보

Fire HazardsFlash point data for this chemical are not available; however, it is probably combustible. (NTP, 1992)
Health HazardsACUTE/CHRONIC HAZARDS: When heated to decomposition this compound emits toxic fumes of NOx. (NTP, 1992)
Reactive GroupAmides and Imides
Reactivity Profile · 1건

N-HYDROXY-2-ACETYLAMINOFLUORENE is an amide. Amides/imides react with azo and diazo compounds to generate toxic gases. Flammable gases are formed by the reaction of organic amides/imides with strong reducing agents. Amides are very weak bases (weaker than water). Imides are less basic yet and in fact react with strong bases to form salts. That is, they can react as acids. Mixing amides with dehydrating agents such as P2O5 or SOCl2 generates the corresponding nitrile. The combustion of these compounds generates mixed oxides of nitrogen (NOx).

Air and Water ReactionsInsoluble in water.

안전 및 보호

Fire FightingFires involving this material can be controlled with a dry chemical, carbon dioxide or Halon extinguisher. (NTP, 1992)
First Aid · 1건

EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.

Nonfire Spill Response · 1건

SMALL SPILLS AND LEAKAGE: Should a spill occur while you are handling this chemical, FIRST REMOVE ALL SOURCES OF IGNITION, then you should dampen the solid spill material with 60-70% ethanol and transfer the dampened material to a suitable container. Use absorbent paper dampened with 60-70% ethanol to pick up any remaining material. Seal the absorbent paper, and any of your clothes, which may be contaminated, in a vapor-tight plastic bag for eventual disposal. Solvent wash all contaminated surfaces with 60-70% ethanol followed by washing with a soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned.

화학 및 산업

약리 정보

Metabolism/MetabolitesN-Hydroxy-2-acetamidofluorene has known human metabolites that include (2S,3S,4S,5R)-6-[acetyl(9H-fluoren-2-yl)amino]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid and 2-Acetylaminofluorene-N-sulfate.
응용 분야 · 2건

용도N-9H-Fluoren-2-yl-N-hydroxy-acetamide inactivates human arylamine N-acetyltransferases (NATs), NAT1 and NAT2. Mutagenicity examined in Salmonella typhimurium TA1538. Liver produced metabolite of the cancinogen 2-Acetamidofluorene (A158535), which is also a highly carcinogenic compound.

일반 설명Cream colored powder.

공급사2 곳

梯希爱(上海)化工贸易有限公司021-61109150 · [email protected]
Shaanxi Didu New Materials Co. Ltd+86-86-17392712779 +86-13289823923 · [email protected]

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이 페이지에서기본 정보개요이름 및 식별자물성안전 및 규제화학 및 산업관련 반응화합물 노트
5896
DTXSID
DTXSID2020719
ChEMBL
CHEMBL284464
ChEBI
CHEBI:17931
UNII
6AGD02HUQC
Nikkaji
J1.912G
Personal Protective Equipment (PPE) · 1건

RECOMMENDED RESPIRATOR: Where the neat test chemical is weighed and diluted, wear a NIOSH-approved half face respirator equipped with a combination filter cartridge, i.e. organic vapor/acid gas/HEPA (specific for organic vapors, HCl, acid gas, SO2 and a high efficiency particulate filter). (NTP, 1992)