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53-96-3CC(=O)Nc1ccc2c(c1)Cc1ccccc1-2CZIHNRWJTSTCEX-UHFFFAOYSA-N53-96-3DTXSID0039227CHEMBL311469CHEBI:17356WHITE TO YELLOW-BROWN CRYSTALLINE POWDER
용도N-(2-Fluorenyl)acetamide (2-Acetamidofluorene, 2-AAF), a genotoxic carcinogen, is used to induce liver cancer in animal models such as the 2-AAF/partial hepatectomy rat. 2-AAF may be used to study the mechanism of liver carcinogenesis and as a reference material during its identification or quantitation.
일반 설명White powder or light beige solid.
생산 방법2-Acetylaminofluorene is produced for research purposes only with an estimated U.S. annual usage of less than 20 lb. It was originally developed as a possible insecticide but has never been used for this purpose after discovery of its carcinogenicity. It is now almost exclusively used in the laboratory studies as a model carcinogen and mutagen.
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정의ChEBI: The parent of the class of 2-acetamidofluorenes, being an ortho-fused polycyclic arene that consists of 9H-fluorene bearing an acetamido substituent at position 2. It is a carcinogenic and mutagenic derivative of fluorene.