Lazucirnon
기본 정보
- CAS
1251528-23-0- 표준 SMILES
Cc1cc(C(=O)N(C)C)cc(NC(=O)[C@H]2CCC(=O)N2C2CCN(Cc3ccc(Cl)c(C)c3)CC2)n1- InChIKey
DWKNOLCXIFYNFV-HSZRJFAPSA-N- 분자식
- C27H34ClN5O3
- 평균 분자량
- 512 g/mol
- 단동위원소 질량
- 511.2350177
개요
ALK-4290 is under investigation in clinical trial NCT03558061 (Evaluate the Effects and Safety of ALK4290 in Patients With Newly Diagnosed Wet Age-Related Macular Degeneration).
이름 및 식별자
- 우선 이름
- Lazucirnon
- IUPAC
- 2-[[(2R)-1-[1-[(4-chloro-3-methylphenyl)methyl]piperidin-4-yl]-5-oxopyrrolidine-2-carbonyl]amino]-N,N,6-trimethylpyridine-4-carboxamide
- 영어명
- ALK-4290
- 분자식
- C27H34ClN5O3
- 분자량
- 512.04
이름 및 동의어
LazucirnonALK4290AKST4290ALK-4290Lazucirnon [USAN]ALK429AKST-4290Lazucirnon (USAN)2-[[(2R)-1-[1-[(4-chloro-3-methylphenyl)methyl]piperidin-4-yl]-5-oxopyrrolidine-2-carbonyl]amino]-N,N,6-trimethylpyridine-4-carboxamideBI144807ALK-429LAZUCIRNON [INN]
이름 더 보기
BI-1448074-Pyridinecarboxamide, 2-[[[(2R)-1-[1-[(4-chloro-3-methylphenyl)methyl]-4-piperidinyl]-5-oxo-2-pyrrolidinyl]carbonyl]amino]-N,N,6-trimethyl-2-[[[(2R)-1-[1-[(4-Chloro-3-methylphenyl)methyl]-4-piperidinyl]-5-oxo-2-pyrrolidinyl]carbonyl]amino]-N,N,6-trimethyl-4-pyridinecarboxamide (ACI)
UNII-R0T9LLR4TNExample 11 [WO2012045803A1]2-((((2R)-1-(1-((4-Chloro-3-methylphenyl)methyl)-4-piperidinyl)-5-oxo-2-pyrrolidinyl)carbonyl)amino)-N,N,6-trimethyl-4-pyridinecarboxamide4-Pyridinecarboxamide, 2-((((2R)-1-(1-((4-chloro-3-methylphenyl)methyl)-4-piperidinyl)-5-oxo-2-pyrrolidinyl)carbonyl)amino)-N,N,6-trimethyl-Example 11 (WO2012045803A1)2-(((2R)-1-(1-((4-chloro-3-methylphenyl)methyl)piperidin-4-yl)-5-oxopyrrolidine-2-carbonyl)amino)-N,N,6-trimethylpyridine-4-carboxamide2-((2R)-1-(1-((4-chloro-3-methylphenyl)methyl)piperidin-4-yl)-5-oxopyrrolidine-2-amido)-N,N,6-trimethylpyridine-4-carboxamide2-((2R)-1-(1-(4-CHLORO-3-METHYLBENZYL)PIPERIDIN-4-YL)-5-OXOPYRROLIDIN-2-CARBOXAMIDO)-N,N,6-TRIMETHYLPYRIDINE-4-CARBOXAMIDE
물성
구조 계산 물성
- XLogP
- 2.9
- 극성 표면적
- 85.9 Ų
- 수소 결합 공여자 수
- 1
- 수소 결합 수용자 수
- 5
- 회전 가능 결합 수
- 6
- 무거운 원자 수
- 36
- 형식 전하
- 0
- 복잡도
- 802
물리화학적 성질
- 끓는 점
- 743.8 · 743.8±60.0 °C(Predicted)
- 밀도
- 1.288 · 1.288±0.06 g/cm3(Predicted)
- 산도 계수 (pKa)
- 11.94 · 11.94±0.20(Predicted)
- 물리적 상태
- Solid
- 색상
- White to off-white
관련 반응
0건
현재 필터 조건에 해당하는 반응 기록이 없습니다.
화합물 노트
불러오는 중…