Uridine Monophosphate

HCID 6030CAS 58-97-9
부분 구조 검색유사 구조 찾기

기본 정보

표준 SMILES
O=c1ccn([C@@H]2O[C@H](COP(=O)(O)O)[C@@H](O)[C@H]2O)c(=O)[nH]1
InChIKey
DJJCXFVJDGTHFX-XVFCMESISA-N
분자식
C9H13N2O9P
평균 분자량
324.18 g/mol
단동위원소 질량
324.03586663

개요

Uridine 5'-monophosphate is a pyrimidine ribonucleoside 5'-monophosphate having uracil as the nucleobase. It has a role as a mouse metabolite, an Escherichia coli metabolite and a human metabolite. It is a uridine 5'-phosphate and a pyrimidine ribonucleoside 5'-monophosphate. It is a conjugate acid of a uridine 5'-monophosphate(2-).

이름 및 식별자

우선 이름
Uridine Monophosphate
IUPAC
[(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl dihydrogen phosphate
영어명
Uridine 5'-monophosphate
분자식
C9H13N2O9P
분자량
324.18

이름 및 동의어

Uridine 5'-monophosphateUridylic acidUridine monophosphateuridine-5'-monophosphateUMP5'-UMPUMP (nucleic acid)Uridine 5'-(dihydrogen phosphate)uridylate5'Uridylic acidBRN 0047486UNII-E2OU15WN0N
이름 더 보기
uridinemonophosphate((2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyriMidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)Methyl dihydrogen phosphateUMP-H5’-umpUMP.H2URIDINE-5'-PHOSPHATEUridine MonophospahteUridine 5’-monophosphteU 5'-P
EINECS 200-408-0E2OU15WN0NCHEBI:166955-24-06-00173 (Beilstein Handbook Reference)Uridylic AcidsAcids, UridylicAcid, UridylicMonophosphate, Uridine

데이터베이스 식별자

CAS
58-97-9
PubChem CID
6030
DTXSID
DTXSID20883211
ChEMBL
CHEMBL214393
ChEBI
CHEBI:16695
UNII
E2OU15WN0N
EC Number
200-408-0
Nikkaji
J4.594B

물성

구조 계산 물성

XLogP
-3.6
극성 표면적
166 Ų
수소 결합 공여자 수
5
수소 결합 수용자 수
9
회전 가능 결합 수
4
무거운 원자 수
21

실험 및 물리화학적 성질

Chemical ClassesBiological Agents -> Nucleic Acids and Derivatives
DrugsPharmaceuticals -> Listed in ZINC15
SpringerMaterials PropertiesAngular frequency
Physical Description · 2건

Solid; [Sigma-Aldrich MSDS]

Solid

Collision Cross Section · 5건

169.81 Ų [M+H]+ [CCS Type: DT; Method: stepped-field]

171.8 Ų [M+Na]+ [CCS Type: DT; Method: single field calibrated with Agilent tune mix (Agilent)]

168 Ų [M+Na]+ [CCS Type: TW; Method: calibrated with polyalanine]

165.7 Ų [M+H]+ [CCS Type: DT; Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]

164.1 Ų [M-2H+Na]-

물리화학적 성질

녹는점
202 °C · 202°C (rough estimate)
밀도
1.865 · 1.865±0.06 g/cm3(Predicted)
저장 조건
-20 °C · -20°C
용해도
2 O: · H2O: 가용성50mg/mL, 투명, 무색
물리적 상태
고체
산도 계수 (pKa)
1 · pK1:6.63 (25°C)

화학적 성질

(Uridine-3′-phosphate) Crystallizes in prisms from methanol. Freely soluble in water and alcohol; dextrorotatory in solution.

안전 및 규제

유해성 정보

Regulatory Information5'-Uridylic acid: Does not have an individual approval but may be used as a component in a product covered by a group standard. It is not approved for use as a chemical in its own right.
Hazards SummaryIntraperitoneal lethal-dose (mouse) > 1,000 mg/kg; [RTECS]

안전 데이터

wgk
3
tsca
TSCA listed
rtecs
YU8088000
HS 번호
29349990
safety_code
24/25
스토리지 클래스
11 - Combustible Solids

화학 및 산업

약리 정보

Tissue LocationsPlacenta
Cellular LocationsCytoplasm
Metabolite PathwaysAmikacin Action Pathway

용도 및 제조

UsesNucleoside found throughout nature; [Merck Index]
General Manufacturing Information5'-Uridylic acid: INACTIVE

응용 분야

용도Biochemical research.

일반 설명Uridine 5'-monophosphate acts as a precursor for all pyrimidine nucleotides.

상·하류 제품 정보

공급사50 곳

广州隽沐生物科技股份有限公司020-36607679; 13502246435 · [email protected]
河北创之源生物科技有限公司13012111162
Hong Kong Tiansheng New Material Trading Co., Ltd+8617320695765 · [email protected]
Baoji Guokang Healthchem co.,ltd+8615604608665 15604608665 · [email protected]
Dayang Chem (Hangzhou) Co.,Ltd.+86-0571-88938639 17705817739 · [email protected]
추가 설명 · 1건

정의The monophosphoric ester of uracil, i.e., the nucleotide containing uracil-d-ribose and phosphoric acid. The phosphate may be esterified to either the 2, 3, or 5 carbon of ribose, yielding uridine-2′-phosphate, uridine-3′phosphate, and uridine-5′-phosphate, respectively.

관련 반응

10건
반응 기록 만들기

연결된 노트

불러오는 중…