Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
모노브로모초산 브롬화물
모노브로모초산브롬화물 · 브로민화브로민아세틸 · 브로민화브로민아세틸(브롬화브롬아세틸) · 브로모아세틸브로마이드 · 2-BROMOACETYL BROMIDE · acetylbromide,bromo- · bromoacetyl · BroMoacetyl br
식별자 및 물리적 특성
| CAS No. | 598-21-0 |
|---|---|
| 분자식 | C2H2Br2O |
| 평균 분자량 | 201.84 g/mol |
| 단동위원소 질량 | 199.84723888 g/mol |
| SMILES | O=C(Br)CBr |
| InChIKey | LSTRKXWIZZZYAS-UHFFFAOYSA-N |
| PubChem CID | 61147 |
| EC No. | 209-923-5 |
| DTXSID | DTXSID1060506 |
| 현지명 | 모노브로모초산 브롬화물 |
화학 및 물리적 성질
| XLogP | 1.6 |
|---|---|
| 극성 표면적 | 17.1 |
| 수소 결합 공여자 수 | 0 |
| 수소 결합 수용자 수 | 1 |
| 회전 가능 결합 수 | 1 |
| 무거운 원자 수 | 5 |
| 형식 전하 | 0 |
| 복잡도 | 42.9 |
| 물질 분류 | Other Classes -> Halogenated KetonesCorrosives |
| SpringerMaterials Properties | Schoenflies notation |
| 밀도 | 2.317 at 68 °F (USCG, 1999) - Denser than waterwill sink2.324 g/mL at 20 °C |
| 끓는 점 | 298 °F at 760 mmHg (USCG, 1999)147-150 °C(lit.) |
| Physical Description | Bromoacetyl bromide appears as a water-white liquid with a pungent odor. Denser than water. Irritates skin, eyes and mucous membranes. May be toxic by ingestion, inhalation and skin absorption. Used to make other chemicals.Fuming water-white liquid with a pungent odor[CAMEO] Colorless to light yellow liquid with an extremely irritating odor[CHRIS] Dark brown liquid[Sigma-Aldrich MSDS] |
| 녹는점 | 148.5°C (estimate) |
| 증기압 | 3.8 mm Hg ( 25 °C) |
| 굴절률 | n20/D 1.547(lit.) |
| 인화점 | >105°C |
| 저장 조건 | Refrigerator (+4°C) |
| 용해도 | 클로로포름에 용해됨 |
| 물리적 상태 | 가루 |
| 색상 | 하얀색 |
| 용해도 | 물과 반응 |
| BRN | 605440 |
| 유전율 | 12.6(20℃) |
| 안정성 | 안정적이지만 물과 격렬하게 반응합니다. 물, 습기, 알코올, 강염기, 강산화제와 호환되지 않습니다. |
| InChI | 1S/C2H2Br2O/c3-1-2(4)5/h1H2 |
| InChIKey | LSTRKXWIZZZYAS-UHFFFAOYSA-N |
| SMILES | BrCC(Br)=O |
| LogP(분배 계수) | -0.04 at 25℃ |
| NIST | Bromoacetyl bromide(598-21-0) |
| EPA | Acetyl bromide, 2-bromo- (598-21-0) |
화학적 성질
dark brown-yellow liquid
안전 및 규제
| GHS 분류 | DangerH314 (100%): Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]P260, P264, P264+P265, P280, P301+P330+P331, P302+P361+P354, P304+P340, P305+P354+P338, P316, P317, P321, P363, P405, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 73 reports by companies from 9 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.Not Classified |
|---|---|
| 규제 정보 | Chemical: Acetyl bromide, bromo-Status: Active Update: 10-05-2022 https://echa.europa.eu/registration-dossier/-/registered-dossier/17142Bromoacetyl bromide: Does not have an individual approval but may be used under an appropriate group standardThe New Jersey Worker and Community Right to Know Act requires public and private employers to provide information about hazardous substances at their workplaces. (N.J.S.A. 34:5A-1 et. seq.) |
| 운송 라벨(DOT) | Corrosive |
| 화재 위험 | Special Hazards of Combustion Products: Heat of fire can cause decomposition, with evolution of highly toxic and irritating hydrogen bromide and bromophosgene vapors.· Combustible material: may burn but does not ignite readily. |
| 건강 유해성 | Inhalation causes severe irritation of upper respiratory system. External contact causes severe irritation of eyes and skin. Ingestion causes severe irritation of mouth and stomach. (USCG, 1999)· TOXIC and/or CORROSIVEinhalation, ingestion or contact (skin, eyes) with vapors, dusts or substance may cause severe injury, burns or death. |
| 유해성 요약 | Reacts violently with water evolving hydrogen bromideCauses severe skin irritation and serious eye injuryBrief contact can cause second- and third-degree skin burns[CHRIS] Readily hydrolyzesCauses burnsInhalation may cause corrosive injuries to upper respiratory tract[Sigma-Aldrich MSDS] See Dichloroacetone. See Hydrogen bromide. |
| 운송 번호 및 가이드(DOT) | 2513 156 |
| 반응성 그룹 | Halogenated Organic Compounds |
| Reactivity Alerts | Water-Reactive |
| Reactivity Profile | BROMOACETYL BROMIDE is incompatible with water, with bases (including amines), with strong oxidizing agents, with alcohols. May react vigorously or explosively if mixed with diisopropyl ether or other ethers in the presence of trace amounts of metal salts [J. Haz. Mat., 1981, 4, 291]. Decomposes when heated with evolution of highly toxic and irritating hydrogen bromide and bromophosgene vapors. |
| DOT Hazard Classification | Bromoacetyl bromideUN2513Class 8 Corrosive material (49 eCFR § 173.136)PG II: the degree of danger presented by the material is medium |
| Air and Water Reactions | Fumes in air. Reacts violently with water to form hydrobromic acid (HBr) (USCG 1991). |
| Hazard Classes and Categories | Skin Irrit. 2 (100%)Corrosives, Reactive agents - 2nd degree |
| 소화 | Excerpt from ERG Guide 156 [Substances - Toxic and/or Corrosive (Combustible / Water-Sensitive)]: |
| 누출 비상 조치 | · CALL 911. Then call emergency response telephone number on shipping paper. If shipping paper not available or no answer, refer to appropriate telephone number listed on the inside back cover.· ELIMINATE all ignition sources (no smoking, flares, sparks or flames) from immediate area. |
| 응급 처치 | INHALATION: Remove from exposuresupport respiration, call physician.General First Aid: |
| 노출 관리 및 개인 보호 | · Wear positive pressure self-contained breathing apparatus (SCBA). |
| 비화재 누출 대응 | Excerpt from ERG Guide 156 [Substances - Toxic and/or Corrosive (Combustible / Water-Sensitive)]: |
| Isolation and Evacuation | Excerpt from ERG Guide 156 [Substances - Toxic and/or Corrosive (Combustible / Water-Sensitive)]:Immediate precautionary measure |
| Personal Protective Equipment (PPE) | Acid-type canister maskself-contained breathing apparatus (full face)rubber gloves and full protective clothing. (USCG, 1999) |
| Emergency Response Planning Guidelines | · Note: Most foams will react with the material and release corrosive/toxic gases. |
| 유해 작용 | Dermatotoxin - Skin burns. |
| 수질 위해 등급(WGK) | 3 |
| TSCA 등재 상태 | TSCA listed |
| 운송 번호(UN) | UN 2513 |
| 관세 코드 | 29159080 |
| 위험 문구(R) | 34-14 |
| 위험 표시 | C |
| 안전 문구(S) | 26-36/37/39-45-8-30-25 |
| 포장분류 | II |
| 위험 등급 | 8Skin Corr. 1B |
| 기존화학 물질 | KE-03617 |
| F 고인화성물질 | 10-19 |
| 저장 분류 | 8A - Combustible corrosive hazardous materials |
용도
용도
Bromoacetyl bromide is widely used in the synthesis of fine chemicals, agrochemicals, dyes and pharmaceuticals. As an acylating agent, it reacts with 10H-phenothiazine to give 10-bromoacetyl-10H-phenothiazine. Similarly, it is also involved in the preparation of bromoactylated starch which is a biodegradable thermoplastic copolymer.
일반 설명
A water-white liquid with a pungent odor. Denser than water. Irritates skin, eyes and mucous membranes. May be toxic by ingestion, inhalation and skin absorption. Used to make other chemicals.